Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0034067 (emphysema)
11,506 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 735 COPD 468 Mol 460 elastin 351 neutrophil elastase 290 alpha 1-antitrypsin 255 collagen 252 FEV 187 She 154 alpha-1-antitrypsin 127 protease inhibitor 120 cytokine 120 matrix metalloproteinase 103 CO2 101 endoplasmic reticulum 84 Alpha-1 antitrypsin 82 HNE 81 MRI 74 AAT 74 MMP-9 73 TNF 71 MMP-12 68 IL-6 61 Pol 60 alpha-1 antitrypsin 58 caspase-3 56 myeloperoxidase 54 vascular endothelial growth factor 54 Mal 53 tumor necrosis factor 51 lymphoid 47 CD8 46 IL-8 45 albumin 45 lipopolysaccharide 45 MMP12 44 superoxide dismutase 43 serine protease inhibitor 42 CD4 40 MMP-2 39 Pseudomonas 36 metalloproteinase 36 chemokine 36 fibronectin 36 glycoprotein 35 TNF-alpha 34 insulin 34 cathepsin G 34 Alpha-1-antitrypsin 34 catalase 34 IFN 32 p53 31 IgE 31 Elastin 31 serine protease 30 GSH 30 IL-13 28 collagenase 28 C-reactive protein 27 klotho 27 LPS 27 SP-D 26 IL-17 26 hemoglobin 26 elastase inhibitor 26 IL-10 26 tropoelastin 25 VEGF 25 anti-elastase 25 lactate dehydrogenase 24 IgA 23 heme oxygenase-1 23 p38 23 inducible nitric oxide synthase 23 cage 23 fibrillin 23 serine proteinase inhibitor 23 IL-4 22 lysyl oxidase 22 Nrf2 21 more...

Disease emphysema 11506 chronic obstructive pulmonary disease 2172 pneumothorax 959 asthma 932 chronic bronchitis 853 lung disease 682 lung cancer 473 COPD 468 pneumonia 421 cancer 407 pulmonary fibrosis 377 bronchiectasis 322 bronchitis 320 bronchitis 319 pulmonary hypertension 291 respiratory failure 248 cystic fibrosis 222 bronchiolitis 218 idiopathic pulmonary fibrosis 217 cirrhosis 207 AAT deficiency 199 interstitial pneumonia 181 tumor 175 liver disease 166 hypertension 163 diabetes 153 tuberculosis 150 interstitial lung disease 146 respiratory disease 133 Thorax 121 bronchopulmonary dysplasia 119 cor pulmonale 107 pneumopericardium 101 sepsis 101 pulmonary edema 98 heart disease 91 sarcoidosis 90 sepsis 89 atherosclerosis 87 pneumoconiosis 85 carcinoma 85 genetic disorder 84 Thoracic 82 tension pneumothorax 80 rheumatoid arthritis 77 pulmonary tuberculosis 76 hernia 76 adult respiratory distress syndrome 75 depression 71 dysphagia 68 obesity 65 heart failure 64 stroke 63 osteoporosis 62 malnutrition 61 adenocarcinoma 57 cardiovascular disease 56 primary pulmonary hypertension 55 influenza 54 myocardial infarction 54 silicosis 53 mediastinitis 52 Langerhans cell histiocytosis 49 hyaline membrane disease 49 pulmonary embolism 49 lymphangioleiomyomatosis 48 lung carcinoma 48 coronary artery disease 46 congestive heart failure 45 small airways disease 44 bronchopneumonia 44 HIV 44 myocardial ischemia 43 empyema 43 cutis laxa 40 hepatocellular carcinoma 40 Boerhaave's syndrome 40 hepatitis 39 vasculitis 39 vascular disease 39 more...

Symptom dyspnea 735 respiratory distress 394 anesthesia 279 cough 270 pain 209 chest pain 151 collapse 145 hemoptysis 107 vomiting 106 hypercapnia 103 shortness of breath 96 wheezing 77 exertional dyspnea 59 abdominal pain 56 cyanosis 48 weakness 43 analgesia 41 diarrhea 40 fatigue 37 hoarseness 34 stridor 31 chronic cough 29 tachypnea 28 neck pain 28 discomfort 26 discomfort 26 sneezing 23 productive cough 23 hyperoxia 21 sore throat 21 nausea 19 anorexia 17 epigastric pain 16 seizures 14 nausea and vomiting 13 clubbing 12 ENT 12 erythema 11 back pain 11 headache 11 angina 11 chest tightness 11 starvation 11 cachexia 11 regurgitation 9 retching 9 ataxia 9 constipation 9 rales 9 hypothermia 9 exhaustion 8 paresis 8 pleuritic chest pain 8 sleepiness 8 shoulder pain 7 Respiratory symptoms 7 nasal discharge 7 thinning 7 Ill 7 tremor 6 persistent cough 6 syncope 6 Air trapping 6 splenomegaly 6 overweight 6 emaciation 5 thigh pain 5 functional recovery 5 pallor 5 labored breathing 5 Lung hyperinflation 5 agitation 5 lethargy 4 rhinorrhea 4 polyuria 4 chills 4 acute abdomen 4 myalgia 4 colic 4 hemiplegia 4 more...

Drug Cardiovasc 153 Asthma 59 Dermatol 29 ascorbate 19 lysine 19 IFN-gamma 17 MRC 14 Prolastin 13 vitamin E 13 ENT 12 ROS 12 Monit 11 Papain 10 Leaf 9 SF6 8 CSF 8 Theophylline 8 Survanta 7 Gel 7 ROC 6 ATV 6 Heme 6 lactose 5 Prednisolone 5 Fraction 5 Vitamin E 5 Helium 5 Glutathione 5 Gelatin 5 Talc 5 ACT 4 p75 4 Ipratropium bromide 4 MAP 4 Dakar 4 CCL 4 Retinoic acid 4 Itraconazole 3 Bayer 3 ICI 3 BCG vaccine 3 CaCl2 3 CaCl2 3 CPR 3 Pirfenidone 3 Sodium hypochlorite 3 G-CSF 3 Vitamin A 3 Ritalin 3 Monensin 3 TTC 3 CaCl2 3 Salbutamol 3 Silica 3 Mutagen 3 Growth hormone 2 TAC 2 Lasalocid 2 PTC 2 Gelfoam 2 SiO2 2 Nephron 2 ETS 2 Spectrum 2 CDX 2 IL-11 2 CPZ 2 Histamine 2 Roflumilast 2 Parkin 2 Atrovent 2 ZnO 2 CDX 2 Xanthium 2 Rolipram 2 Biopolymers 2 PCP 2 SBT 2 TPV 2 Prednisone 2 more...

Enzyme elastase 724 neutrophil elastase 341 papain 94 trypsin 77 aspartate aminotransferase 65 peroxidase 59 collagenase 58 superoxide dismutase 50 mitogen-activated protein kinase 46 catalase 45 caspase-3 45 macrophage elastase 38 cathepsin G 34 ERK 34 lactate dehydrogenase 27 glutathione peroxidase 21 BAL 19 phosphodiesterase 19 lysyl oxidase 18 thrombin 17 focal adhesion kinase 17 chymotrypsin 15 proteasome 14 MMP 14 alkaline phosphatase 13 NADPH oxidase 11 MIP 11 matrix metalloproteinase 9 11 cathepsin L 11 NADPH oxidase 10 alanine aminotransferase 10 ACE 10 plasmin 10 reverse transcriptase 9 interstitial collagenase 9 beta-glucuronidase 9 cathepsin S 8 ATPase 8 microsomal epoxide hydrolase 8 glutathione reductase 8 protein kinase C 8 xanthine oxidase 7 cathepsin B 7 thromboplastin 7 succinate dehydrogenase 7 acid phosphatase 7 luciferase 7 SPC 7 kallikrein 7 MMP-3 7 renin 7 caspase-1 6 heme oxygenase 6 glutathione S-transferase 6 protein kinase 6 ceruloplasmin 5 MEK 5 AST 5 glucose-6-phosphate dehydrogenase 5 NQO1 5 soluble epoxide hydrolase 5 lysozyme 5 neutral sphingomyelinase 5 proteinase-3 5 urokinase-type plasminogen activator 5 glucose oxidase 4 cathepsin K 4 AMP-activated protein kinase 4 acetylcholinesterase 4 gamma-glutamylcysteine synthetase 4 NO synthase 4 CAD 4 diaphorase 4 CAD 4 CPR 4 chitinase 4 CAD 4 beta-lactamase 4 lipoxygenase 4 matrix metalloproteinase 2 3 more...

Compound Dec 822 oxygen 727 Clin 677 CO2 393 water 222 DNA 193 serine 111 nitrogen 92 His 79 TNF 71 calcium 61 Pac 58 cysteine 56 hydrogen 55 AAT 55 cadmium 54 sodium 53 nitric oxide 50 glucose 43 retinoic acid 41 iron 40 phosphate 40 methionine 39 GSH 36 GSH 36 lysine 36 Cardiol 35 barium 33 Elastin 31 alanine 30 copper 30 acetate 28 sulfate 27 zinc 27 bromide 26 Phe 25 H2O2 25 3-methylindole 24 tryptophan 24 urea 24 tryptophan 23 tryptophan 23 tryptophan 23 creatinine 22 leucine 20 N-acetylcysteine 20 aluminum 19 BAL 19 salt 18 arginine 18 valine 17 vitamin D 16 ethanol 15 Optimal 15 silicon 15 ATP 15 proline 15 formaldehyde 15 iodine 14 dUTP 14 Collagen 14 Nicotine 14 threonine 14 tyrosine 14 Theophylline 13 NH2 13 titanium 12 formaldehyde 12 CAT 11 N2O 11 CAT 11 ASA 11 CAT 11 Serine 11 PAS 11 glutamate 10 chromium 10 nickel 10 nitrate 10 CdCl2 10 more...

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