Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0034067 (
emphysema
)
11,506
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
735
COPD
468
Mol
460
elastin
351
neutrophil elastase
290
alpha 1-antitrypsin
255
collagen
252
FEV
187
She
154
alpha-1-antitrypsin
127
protease inhibitor
120
cytokine
120
matrix metalloproteinase
103
CO2
101
endoplasmic reticulum
84
Alpha-1 antitrypsin
82
HNE
81
MRI
74
AAT
74
MMP-9
73
TNF
71
MMP-12
68
IL-6
61
Pol
60
alpha-1 antitrypsin
58
caspase-3
56
vascular endothelial growth factor
54
myeloperoxidase
54
Mal
53
tumor necrosis factor
51
lymphoid
47
CD8
46
albumin
45
lipopolysaccharide
45
IL-8
45
MMP12
44
superoxide dismutase
43
serine protease inhibitor
42
CD4
40
MMP-2
39
more...
Disease
emphysema
11506
chronic obstructive pulmonary disease
2172
pneumothorax
959
asthma
932
chronic bronchitis
853
lung disease
682
lung cancer
473
COPD
468
pneumonia
421
cancer
407
pulmonary fibrosis
377
bronchiectasis
322
bronchitis
320
bronchitis
319
pulmonary hypertension
291
respiratory failure
248
cystic fibrosis
222
bronchiolitis
218
idiopathic pulmonary fibrosis
217
cirrhosis
207
AAT deficiency
199
interstitial pneumonia
181
tumor
175
liver disease
166
hypertension
163
diabetes
153
tuberculosis
150
interstitial lung disease
146
respiratory disease
133
Thorax
121
bronchopulmonary dysplasia
119
cor pulmonale
107
pneumopericardium
101
sepsis
101
pulmonary edema
98
heart disease
91
sarcoidosis
90
sepsis
89
atherosclerosis
87
pneumoconiosis
85
more...
Symptom
dyspnea
735
respiratory distress
394
anesthesia
279
cough
270
pain
209
chest pain
151
collapse
145
hemoptysis
107
vomiting
106
hypercapnia
103
shortness of breath
96
wheezing
77
exertional dyspnea
59
abdominal pain
56
cyanosis
48
weakness
43
analgesia
41
diarrhea
40
fatigue
37
hoarseness
34
stridor
31
chronic cough
29
tachypnea
28
neck pain
28
discomfort
26
discomfort
26
sneezing
23
productive cough
23
hyperoxia
21
sore throat
21
nausea
19
anorexia
17
epigastric pain
16
seizures
14
nausea and vomiting
13
ENT
12
clubbing
12
starvation
11
chest tightness
11
back pain
11
more...
Drug
Cardiovasc
153
Asthma
59
Dermatol
29
lysine
19
ascorbate
19
IFN-gamma
17
MRC
14
Prolastin
13
vitamin E
13
ROS
12
ENT
12
Monit
11
Papain
10
Leaf
9
Theophylline
8
SF6
8
CSF
8
Survanta
7
Gel
7
ROC
6
Heme
6
ATV
6
Glutathione
5
lactose
5
Helium
5
Fraction
5
Talc
5
Gelatin
5
Prednisolone
5
Vitamin E
5
Retinoic acid
4
MAP
4
CCL
4
p75
4
ACT
4
Ipratropium bromide
4
Dakar
4
Bayer
3
Pirfenidone
3
BCG vaccine
3
more...
Enzyme
elastase
724
neutrophil elastase
341
papain
94
trypsin
77
aspartate aminotransferase
65
peroxidase
59
collagenase
58
superoxide dismutase
50
mitogen-activated protein kinase
46
caspase-3
45
catalase
45
macrophage elastase
38
ERK
34
cathepsin G
34
lactate dehydrogenase
27
glutathione peroxidase
21
BAL
19
phosphodiesterase
19
lysyl oxidase
18
focal adhesion kinase
17
thrombin
17
chymotrypsin
15
MMP
14
proteasome
14
alkaline phosphatase
13
matrix metalloproteinase 9
11
cathepsin L
11
MIP
11
NADPH oxidase
11
NADPH oxidase
10
plasmin
10
alanine aminotransferase
10
ACE
10
beta-glucuronidase
9
interstitial collagenase
9
reverse transcriptase
9
protein kinase C
8
microsomal epoxide hydrolase
8
glutathione reductase
8
ATPase
8
more...
Compound
Dec
822
oxygen
727
Clin
677
CO2
393
water
222
DNA
193
serine
111
nitrogen
92
His
79
TNF
71
calcium
61
Pac
58
cysteine
56
hydrogen
55
AAT
55
cadmium
54
sodium
53
nitric oxide
50
glucose
43
retinoic acid
41
iron
40
phosphate
40
methionine
39
lysine
36
GSH
36
GSH
36
Cardiol
35
barium
33
Elastin
31
alanine
30
copper
30
acetate
28
zinc
27
sulfate
27
bromide
26
H2O2
25
Phe
25
tryptophan
24
urea
24
3-methylindole
24
more...