Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0034067 (emphysema)
11,506 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 735
COPD 468
Mol 460
elastin 351
neutrophil elastase 290
alpha 1-antitrypsin 255
collagen 252
FEV 187
She 154
alpha-1-antitrypsin 127
protease inhibitor 120
cytokine 120
matrix metalloproteinase 103
CO2 101
endoplasmic reticulum 84
Alpha-1 antitrypsin 82
HNE 81
MRI 74
AAT 74
MMP-9 73
TNF 71
MMP-12 68
IL-6 61
Pol 60
alpha-1 antitrypsin 58
caspase-3 56
vascular endothelial growth factor 54
myeloperoxidase 54
Mal 53
tumor necrosis factor 51
lymphoid 47
CD8 46
albumin 45
lipopolysaccharide 45
IL-8 45
MMP12 44
superoxide dismutase 43
serine protease inhibitor 42
CD4 40
MMP-2 39
more...
Disease
emphysema 11506
chronic obstructive pulmonary disease 2172
pneumothorax 959
asthma 932
chronic bronchitis 853
lung disease 682
lung cancer 473
COPD 468
pneumonia 421
cancer 407
pulmonary fibrosis 377
bronchiectasis 322
bronchitis 320
bronchitis 319
pulmonary hypertension 291
respiratory failure 248
cystic fibrosis 222
bronchiolitis 218
idiopathic pulmonary fibrosis 217
cirrhosis 207
AAT deficiency 199
interstitial pneumonia 181
tumor 175
liver disease 166
hypertension 163
diabetes 153
tuberculosis 150
interstitial lung disease 146
respiratory disease 133
Thorax 121
bronchopulmonary dysplasia 119
cor pulmonale 107
pneumopericardium 101
sepsis 101
pulmonary edema 98
heart disease 91
sarcoidosis 90
sepsis 89
atherosclerosis 87
pneumoconiosis 85
more...
Symptom
dyspnea 735
respiratory distress 394
anesthesia 279
cough 270
pain 209
chest pain 151
collapse 145
hemoptysis 107
vomiting 106
hypercapnia 103
shortness of breath 96
wheezing 77
exertional dyspnea 59
abdominal pain 56
cyanosis 48
weakness 43
analgesia 41
diarrhea 40
fatigue 37
hoarseness 34
stridor 31
chronic cough 29
tachypnea 28
neck pain 28
discomfort 26
discomfort 26
sneezing 23
productive cough 23
hyperoxia 21
sore throat 21
nausea 19
anorexia 17
epigastric pain 16
seizures 14
nausea and vomiting 13
ENT 12
clubbing 12
starvation 11
chest tightness 11
back pain 11
more...
Drug
Cardiovasc 153
Asthma 59
Dermatol 29
lysine 19
ascorbate 19
IFN-gamma 17
MRC 14
Prolastin 13
vitamin E 13
ROS 12
ENT 12
Monit 11
Papain 10
Leaf 9
Theophylline 8
SF6 8
CSF 8
Survanta 7
Gel 7
ROC 6
Heme 6
ATV 6
Glutathione 5
lactose 5
Helium 5
Fraction 5
Talc 5
Gelatin 5
Prednisolone 5
Vitamin E 5
Retinoic acid 4
MAP 4
CCL 4
p75 4
ACT 4
Ipratropium bromide 4
Dakar 4
Bayer 3
Pirfenidone 3
BCG vaccine 3
more...
Enzyme
elastase 724
neutrophil elastase 341
papain 94
trypsin 77
aspartate aminotransferase 65
peroxidase 59
collagenase 58
superoxide dismutase 50
mitogen-activated protein kinase 46
caspase-3 45
catalase 45
macrophage elastase 38
ERK 34
cathepsin G 34
lactate dehydrogenase 27
glutathione peroxidase 21
BAL 19
phosphodiesterase 19
lysyl oxidase 18
focal adhesion kinase 17
thrombin 17
chymotrypsin 15
MMP 14
proteasome 14
alkaline phosphatase 13
matrix metalloproteinase 9 11
cathepsin L 11
MIP 11
NADPH oxidase 11
NADPH oxidase 10
plasmin 10
alanine aminotransferase 10
ACE 10
beta-glucuronidase 9
interstitial collagenase 9
reverse transcriptase 9
protein kinase C 8
microsomal epoxide hydrolase 8
glutathione reductase 8
ATPase 8
more...
Compound
Dec 822
oxygen 727
Clin 677
CO2 393
water 222
DNA 193
serine 111
nitrogen 92
His 79
TNF 71
calcium 61
Pac 58
cysteine 56
hydrogen 55
AAT 55
cadmium 54
sodium 53
nitric oxide 50
glucose 43
retinoic acid 41
iron 40
phosphate 40
methionine 39
lysine 36
GSH 36
GSH 36
Cardiol 35
barium 33
Elastin 31
alanine 30
copper 30
acetate 28
zinc 27
sulfate 27
bromide 26
H2O2 25
Phe 25
tryptophan 24
urea 24
3-methylindole 24
more...