Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0034067 (
emphysema
)
11,506
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Occupation and industry codes on death certificates from 23 states for 1984-1988 were used to evaluate mortality risks among white and nonwhite, male and female farmers. Proportionate mortality and proportionate cancer mortality ratios were calculated using deaths among nonfarmers from the same states to generate expected numbers. Among farmers there were 119,648 deaths among white men, 2,400 among white women, 11,446 among nonwhite men, and 2,066 among nonwhite women. Deficits occurred in all race-sex groups for infective and parasitic diseases, all cancer combined, lung cancer, liver cancer, diseases of the nervous system, multiple sclerosis, hypertension, and
emphysema
. As reported in other studies, white male farmers had excesses of cancer of the lymphatic and hematopoietic system, lip, eye, brain, and prostate. Excesses of cancers of the pancreas, kidney, bone, and thyroid were new findings. Regional patterns were evident, particularly among white men. Significant excesses for accidents, vascular lesions of the central nervous system (CNS), and cancers of the prostate tended to occur in most geographic regions, while excesses for mechanical suffocation,
non-Hodgkin's lymphoma
, and cancers of the lip, brain, and the lymphatic and hematopoietic system were limited to the Central states. Increases among nonwhite men were similar to those in white men for some causes of death (vascular lesions of the CNS and cancers of the pancreas and prostate), but were absent for others (lymphatic and hematopoietic system, lip, eye, kidney, and brain). Women (white and nonwhite) had excesses for vascular lesions of the CNS, disease of the genitourinary system (white women only), and cancers of the stomach and cervix (nonwhite women only). Cancer of the buccal cavity and pharynx was slightly elevated among women, and white women had nonsignificant excesses of multiple myeloma and leukemia. Excesses for leukemia and
non-Hodgkin's lymphoma
occurred among white men and women, but not among nonwhites. Excesses for several types of accidental deaths were seen among all race-sex groups.
...
PMID:Cancer and other causes of death among male and female farmers from twenty-three states. 850 51
A proportionate mortality study of a cohort of golf course superintendents was conducted using death certificates for 686 deceased members of the Golf Course Superintendents Association of America who died from 1970 to 1992. White males were included in the study population from all 50 states. The study objective was to compare mortality from this cohort to the general U.S. white male population. The proportionate mortality ratio (PMR) for all types of cancer was 136 (CI: 121, 152). Significant excess mortality from smoking-related diseases was observed. The PMR for arteriosclerotic heart disease was 140, which was significantly elevated (CI: 127, 155). In addition, the PMR for all respiratory diseases was 176 (CI: 135,230), while the PMR for
emphysema
was 186 (CI: 101,342). The PMR for lung cancer was 117 (CI: 93, 148). Mortality for four cancer types--brain, lymphoma (
non-Hodgkin's lymphoma
,
NHL
), prostate, and large intestine--occurred at elevated levels within this cohort: brain cancer PMR = 234 (CI: 121,454),
non-Hodgkin's lymphoma
(
NHL
) PMR = 237 (CI: 137,410), prostate cancer PMR = 293 (CI: 187,460), and large intestine cancer PMR = 175 (CI: 125,245). The PMR for diseases of the nervous system was 202 (CI: 123,333). A similar pattern of elevated
NHL
, brain, and prostate cancer mortality along with excess deaths from diseases of the nervous system has been noted among other occupational cohorts exposed to pesticides.
...
PMID:Proportionate mortality study of golf course superintendents. 913 Dec 18
A 57-year-old woman with
non-Hodgkin's lymphoma
presented to the emergency department with febrile neutropaenia. She complained of fever and malaise and had a normal physical examination. Ten hours later, she developed worsening right leg pain that required escalating doses of morphine. Her physical examination remained unremarkable. Owing to the increasing pain in her leg, an x-ray was performed which revealed subcutaneous
emphysema
. She subsequently developed numbness over her right leg and, then, 21 h after admission the leg became cold and ischaemic. Haemorrhagic bullae and bruising began to form and crepitus was palpated. She was taken to the operating room where debridement was attempted, but the surgeons found deep and extensive tissue necrosis. She was transferred to the intensive care unit for a trial of medical therapy and eventual palliation. The pathology revealed severe myonecrosis secondary to Clostridium septicum. She expired 36 h after presentation.
...
PMID:Medical cause of compartment syndrome: a fatal case of Clostridium septicum. 2266 29