Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0034067 (emphysema)
 11,506 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Organic solvent inhalation leading to intoxication has become an important medical problem. Pulmonary function studies were performed on 42 young (ages 11-31) solvent inhalers and on 20 controls (ages 10-26). Ventilatory studies were normal in the majority, but residual volumes of inhalers were significantly higher (136.26% +/- 32.64% S.C.) than in controls (104% +/- 27.78% S.C.)--p less than 0.001. Lung tissue obtained at autopsy, from three known solvent inhalers was found to contain microscopic abnormalities similar to those seen in experimental panlobular emphysema and it is assumed these changes are consistent with increased residual volumes.
Adv Alcohol Subst Abuse 1984
PMID:Solvent abuse associated pulmonary abnormalities. 649 34

An attempt to eliminate smoking from the CCF chemical dependency unit resulted from an institutional mandate that the campus be smoke-free. Initially, patients were given the option of either not smoking or smoking outside with staff supervision. Those who opted for smoking cessation received no specific treatment for nicotine addiction, but were only given snacks, therapeutic activities, and stress management techniques to aid in their effort. The initiative failed. Patient and staff resistance, hazardous conditions due to surreptitious smoking, and interference with other treatment components led to suspension of the policy. A second attempt, thought to be a superior design, included therapeutic interventions similar to traditional addiction treatment; however, it also failed to produce nicotine recovery in most patients. It was noted that patients with such adverse consequences from nicotine as emphysema or cancer could be motivated to recover from nicotine addiction and were helpful in motivating those without consequences to stop smoking. Significantly, despite several patients' refusal to enter or continue in treatment due to the no smoking policy, unit census actually increased.
J Subst Abuse Treat
PMID:A smoke-free chemical dependency unit. The Cleveland Clinic experience. 838 92

Generalized resistance to disease and reduced tendency to depression have been related to the extent of social relationships, with a greater association for females than males. Cigaret smoking is the largest cause of preventable death: smokers' mortality rates are almost double those for non-smokers. Coronary heart disease and lung cancer are the main causes of death. Morbidity is also higher among smokers, who are more prone to bronchitis, emphysema, sinusitis, peptic ulcers, and influenza. Abuse of drugs, both prescribed and unprescribed, is linked directly to drug dependency and death, often suicide. Misuse of prescribed drugs is a major concern in the elderly. High caffeine consumption has been related to chronic insomnia, persistent anxiety and depression, and stomach upset. Use of properly adjusted seatbelts halves the number of deaths and the severity of injury in motor vehicle accidents. Type A personality behaviors are associated with an increased risk of coronary heart disease. "Insight" requires further study to assess its affect on health and wellbeing. Quality of working life is an important determinant of an individual's identity and health status: frequency of symptoms increase as job strain increases.
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PMID:Health consequences of selected lifestyle factors: a review of the evidence, part 2. 2127 53