Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034067 (emphysema)
11,506 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The aim of the paper was the analysis of 1450 laparoscopic procedures performed in the Clinic of Gynecology--IOG PMA in Szczecin in the years from 1974 to 1992. The above number include 320 laparoscopic operations. In the analyzed three five-year periods, the number of laparoscopies increased twofold, while in the years 1989-1992 it constituted 26.8% of all the operative procedures. Indication for laparoscopy in 74.6% of cases was sterility, in 13.38% pelvic pain of undefined etiology, in 7.7% ectopic pregnancy, 1.8% oncologic indications, in 0.5% internal ones, in 0.3% sterilization and others in 1.6%. Among operative laparoscopies electrocoagulation of endometriosis was carried out in 46.6% of cases, resection of intraperitoneal adhesions in 27.5%, in the region of abdominal orifices of oviducts in 7.5%, ectopic pregnancy operations in 7.2%, excision of ovarian cysts in 6.6% as well as extirpation of myomas in 4.7%. At the analyzed period the following complications were disclosed, namely: interstitial lesion in 2 cases, hemorrhage from inferior epigastric artery in 1 and subcutaneous emphysema in 34 cases.
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PMID:[Nineteen years of laparoscopy in the gynecology clinic IPG PAM]. 130 76

Laparoscopy is reviewed in this keynote lecture of the 1st annual meeting of the American Association of Gynecological Laparoscopists in Las Vegas, Nevada, November 1972. The pneumoperitoneum may produce pressure on the inferior vena cava and stomach and cause splinting of the diaphragm leading to impaired ventilation, reduction in venous return to the heart, and possible regurgitation of stomach contents. Absorption of carbon dioxide may cause a rise of partial pressure of carbon dioxide with associated cardiac arrhythmias. All of these problems are controlled or prevented by a general anesthetic with intubation by a cuff tube, good muscle relaxation, and controlled ventilation by a respirator. Laparoscopy may be used to determine intact ectopic pregnancy and study female sterility, early endometriosis, acute salpingitis, chronic pelvic inflammatory disease, small uterine or other masses, and primary and secondary amenorrhea. Surgical uses include puncture and/or aspiration of ovarian cysts or tubo-ovarian cysts, removal of foreign bodies, resection of adhesions, tubal sterilization, and ventrosuspension of uterus. Contraindications include difficulty in establishing an adequate pneumoperitoneum; acute peritonitis, ileus, or intestinal obstruction; and inadvisability of penumoperitoneum or Trendelenburg position. Laparoscopy can diagnose the extent and nature of pelvic and abdominal cancer and evaluate treatment. Reported complications with laparoscopy include puncture of vessels, perforation of intra-abdominal viscus, parietal or omental emphysema, cardiorespiratory embarrassment, and effects of high-pressure gas injections. A woman infertile due to absent or useless oviducts but with a healthy uterus and at least 1 healthy functioning ovary could seemingly be assisted through recovery of oocytes via laparoscopy, fertilization and cleavage of the ovum in vitro, and finally embryo transfer into her uterus. The first 2 steps have already been accomplished for women.
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PMID:Gynecological laparoscopy. 426 3

A description of a film shot with a laparoscope film setup precedes a discussion of the development and present use of laparoscopy. The film shows the rupturing of a follicle. Problems encountered in the European development of laparoscopy included need to modify the optical instruments of the gastroenterologists, inadequacy of illumination, and selection of a usable gas for the pneumoperitoneum. Operative laparoscopy is used for tubal sterilization, biopsy is suspected carcinoma or tuberculosis, aspiration of ovarian cysts, wedge resection of the ovary, resection of adhesions, cauterization of endometriotic lesions, resection of sacrouterine ligaments, ventrosuspension of the uterus, and liver biopsy. Tubal sterilization is the most common procedure. Complications due to technical failure include emphysema, gas embolism hemorrhage, hemotoma, intestinal perforation, gastric perforation, and respiratory and circulatory embarrassment. Complications occurring during operative procedures, excluding complications of tubal sterilization, include burning of skin, burning of intestines, necroses of intestines, peritonitis, late hemorrhage, and electric shock by high-frequency current.
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PMID:On the development of gynecologic laparoscopy. A recording of human ovulation. 426 4

The ACTA-Scanner has virtually unlimited potential in the evalution of any part of the body. The usefulness of the technique has already been shown in the appraisal of pathologies of the brain and cerebrospinal fluid cavities. The orbits and the eyeballs, the facial sinuses, and skull base lesions have also been elucidated. Tumors of the larynx, pharynx, thyroid, and parathyroid; lymphomas; and pathology of the spine and spinal cord are well within the reach of this new diagnostic methodology. Lung pathologies, such as emphysema, pneumonias, neoplasms, infarctions, pleural effusions and granulomatous diseases, and mediastinal pathology represent a challenging complex of lesions to be appraised by ACTA-scanning. For the heart, there is great potential for observing cardiac chamber size, hypertrophy of ventricular or atrial walls, and ventricular or aortic aneurysms, and possibly for recognizing the damaged myocardial tissue immediately after or some time after an infarction. The abdominal pathologies that can be studied are almost uncountable: gastric neoplasms, pancreatic cysts and stones, gallstones, neoplasms of the liver and pancreas, bowel tumors, abdominal aortic aneurysms, renal neoplasms and cysts, atrophy of the kidneys, bladder tumors, uterine tumors, ovarian cysts, and many more. Although bones and joints are adequately demonstrated by conventional x-ray techniques, there is no doubt that as the new technique is developed ACTA-grams will contribute significant information in the transverse plane, as well as in densitometric analyses. The impact of ACTA-scanning will not be limited to the diagnostic area, but will extend, at least indirectly, to general patient management and to some aspects of medical economics as well. Risk-laden, technically complex, and costly diagnostic procedures, sometimes requiring lengthy hospitalization, will in some cases be eliminated. The simple, innocuous, and noninvasive ACTA-scanning can be performed on an outpatient basis. Repeated follow-up examinations should be easily accepted by the patients, considering that this diagnostic test is carried out without discomfort. The entire field of diagnostic radiology is on the verge of revolutionary changes.
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PMID:Computerized transaxial x-ray tomography of the human body. 460 76

1. Endosulfan insecticide is a polychlorinated compound used for controlling a variety of insects; it is practically water-insoluble, but readily adheres to clay particles and persists in soil and water for several years. Its mode of action involves repetitive nerve-discharges positively correlated to increase in temperature. This compound is extremely toxic to most fish and can cause massive mortalities. In fish, it causes marked changes in Na and K concentrations, decrease in blood Ca(2+) and Mg levels and inhibits Na, K and Mg-dependent ATPase (in brain). 2. Bioaccumulation of endosulfan is reported for marine animals; however, freshwater animals (e.g., crayfish) accumulate it to some extent, but they lose the compound rapidly during depuration. Endosulfan is generally less toxic to aquatic invertebrates than fish. However, it causes decreases in adenylate energy charge, oxygen consumption, hemolymph amino acids, succinate dehydrogenase, heart-beat (mussel) and altered osmoregulation. 3. Generally, mammals are less susceptible to endosulfan's toxicity than aquatic animals. The majority of studies conducted on laboratory mammals can be summarized. (a) Neurotoxicity: male rats are more sensitive than females to endosulfan, which decreases brain and plasma acetylcholinesterase activity. Endosulfan I (a metabolite) causes a significant change in norepinephrine, 5-HT and GABA. (b) Renal toxicity: inhibition of MFOs activity was noticed in rats; other effects included changes in proximal convoluted tubules and necrosis of the tubular epithelium. (c) Hepatotoxicity: chemically-induced aminopyrine N-demethylase and aniline hydrolase were found in rat liver, and reduction in the glycogen level occurred. (d) Hematologic toxicity: endosulfan exposure resulted in a significant decrease in the level occurred. (d) Hematologic toxicity: endosulfan exposure resulted in a significant decrease in the erythrocyte glutathione reductase, hemoglobin amount, RBC number and mean corpuscular volume. 4. Respiratory toxicity: involved dyspnea, acute emphysema, cyanosis and hemorrhages in teh interalveolar portions of rat's lungs. 5. Biochemical: in rats, endosulfan caused increased glucose-6-phosphate dehydrogenase activity, blood glucose level, phospholipid contents of the microsomal and surfactant system, and profoundly induced the activity of alcohol dehydrogenase and cytosolic glutathione S-transferases. It also decreased significantly Na+, K+ and Mg(2+) ATPases, plasma calcium level and alkaline phosphatase in the intestinal epithelium. 6. Immunologic toxicity: rat serum antibody titer to tetanus toxin, IgG, IgM and gammaglobulins were significantly reduced. 7. Reproductive toxicity: degenerative changes in the seminiferous epithelium, induction of the rate-limiting enzyme in testosterone production (3beta-hydroxysteroid transferase and 17 beta-hydroxysteroid transferase), histological changes in reproductive organs, testicular atrophy and the occurrence of ovarian cysts were noticed in rat. Reduction in the weight of secondary sex organ was also observed.(ABSTRACT TRUNCATED AT 400 WORDS)
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PMID:Bioaccumulative potential and toxicity of endosulfan insecticide to non-target animals. 790 Sep 59

This study was undertaken to evaluate the clinical usefulness of operative laparoscopy in treatment of benign ovarian cysts. A retrospective study was carried on 468 operative laparoscopy cases performed from September 1995 to September 1998 at Yonsei University College of Medicine, Department of Obstetrics and Gynecology. Patient characteristics, specimen pathology, perioperative morbidity, and perioperative complications were reviewed. The percentage of operative laparoscopy increased steadily from 20.7% in 1996, 33.9% in 1997, to 49.7% in 1998. The mean age of patients was 33.66.5 (mean +/- SD) years and the mean hospital stay was less than 2 days. Types of surgery performed were cystectomy (n = 234), salpingo-oophorectomy (n = 126), oophorectomy (n = 63), and fulguration (n = 45), in decreasing order. Depending on the pathology of the ovarian cyst, the mean operation time was in the range of 80 to 110 minutes. Perioperative complications included 5 cases of subcutaneous emphysema, 10 cases of abdominal wall hematoma, 7 cases of trocar site bleeding, 3 cases of bowel injury, and 1 case of bladder injury. In conclusion, operative laparoscopy in treating benign ovarian cysts provides advantages such as less need to perform laparotomy, smaller skin incision, less perioperative discomfort, minimal tissue handling and trauma, and shorter hospital stay. Nevertheless, the risk of unrecognized ovarian malignancy cannot be absolutely excluded, therefore careful patient selection is mandated.
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PMID:Operative laparoscopy in treating benign ovarian cysts. 1066 Oct 40

Some aspects were studied of origination of uterine myoma and ovarian cyst in 121 women younger than 35 years of age presenting with chronic obstructive bronchopulmonary pathology. Uterine and ovarian benign tumors are more likely to develop against the background of chronic obstructive pulmonary pathology in the presence of respiratory failure, pulmonary emphysema, bronchiectatic disease, grave progress of the illness, development of lung disease at age, less than 10, with the above disease being more than ten years in duration.
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PMID:[Benign tumors of the uterus and ovaries in women with chronic obstructive bronchopulmonary diseases]. 1103 56

270 women underwent laparoscopic tubal sterilizations with Yoon silicone rings at the Obstetrics and Gynecology clinic of the Dakar teaching hospital in Senegal between 1979-84. Written consent of the husband was required for all married women. 235 women underwent sterilization because of grand multiparity and 34 for medical reasons. The medical indications included 1 case of cardiopathy, 12 of severe psychosis, and 3 of serious vasculorenal syndrome. 70 operations were done under local and 200 under general anesthesia. 1 patient was 20 years old and the rest were 33-44. The average age was 32 and the average parity was 8. Observations during the laparoscopies included 40 cases of pelvic adhesions, 10 of uterine retroversion, 30 of congestive tubes, and 13 of ovarian cysts. Placement of the rings was usually accomplished easily 2-3 cm from the cornu. In 6 cases, rings were lost in the peritoneal cavity and in 14 cases a tube was ruptured. In 1 case the extent of a patient's obesity was underestimated and an IUD was inserted instead of a ring. 1 case of allergy to pethidine and 1 case of subcutaneous emphysema were observed. 174 follow-up hysterosalpingographies were done. 1 pregnancy occurred 4 months after the sterilization operation. Postpartum hysterosalpingography revealed a broken ring. The period of hospitalization varied from 48-72 hours and averaged 60 hours.
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PMID:[Tubal sterilization using the Yoon silicone ring: 270 cases at the Obstetric Gynecological Clinic of DANTEC Teaching Hospital, Senegal]. 1231 25

Patients with advanced cancer often develop enterocutaneous fistulae. The enterocutaneous fistulae usually develop from gastrointestinal malignancies. We describe a case report of a patient with schwannoma of the ovarian cyst wall who developed enterocutaneous fistula but presented with subcutaneous emphysema.
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PMID:Subcutaneous emphysema: an uncommon presentation of enterocutaneous fistula. 1464 64