Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034067 (emphysema)
 11,506 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Of the 1029 thoracic surgeries carried out since 1950 at the Second and later at the Third Surgical, University Clinic in Budapest on infants, children, and adolescents 215 were cases to correct some developmental anomaly. Pulmonary cysts--both single and multiple--represent the largest number, followed by lung-sequestration, lobar emphysema, and bronchial arterioma. To assess the late results, 106 ex-patients were invited to the clinic for check-up. They had beed operated at least 10 years before; the longest follow-up time was 23 years. Eighty-nine (83.9%) of the 106 patients appeared at the clinic. One pulmonectomized for a polycystic lung (0.9%) died in the meantime; 16 were not available. The 89 patients were submitted to a clinical examination, including radiological examination, spirometry, and ECG. With one exception (Kartagener syndrome), they were found in good condition and free of complaints. They carried on some studies or worked in different jobs. There were no relapses. They developed very satisfactorily no matter whether their operations took place in infancy, childhood or adolescence. The surgical intervention did not affect growth and development. Congenital pulmonary malformations and disorders should be treated by surgery, and the long-term results are better if the operation is performed at the proper time.
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PMID:Long-term results of the surgical treatment for pulmonary malformations and disorders. 86 83

Histologic and ultrastructural pulmonary changes in a female with a classical Zivert-Kartagener's syndrome are described. Congenital anomalies of the columnar epithelium brushes as well as defects acquired in the process of inflammation (decreased number and various length of bruches with their orientation disturbances, additional doublets and the lack of basal bodies) were revealed at transmission and scanning microscopy level. Follicular bronchiectasis, chronic pneumonia, dystelectasies, emphysema result from the mucociliary clearance disturbance and are of an acquired nature.
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PMID:[Morphologic lung changes in a female patient with Zivert-Kartagener's syndrome]. 179 21