Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034067 (emphysema)
 11,506 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

85 cases of measles with complications have been reported in Agades (Niger) from September 1983 to March 1985. The patients were all adults more than 15 years of age. Such complications are more frequent during winter season. The disease is superposable to the one observed in children: same course, same types of complications (superinfection, undernutrition, dehydration, broken compensation of a parasitosis, encephalitis). Mortality rate is next to the one observed in child (18.2%). Death occurs mainly in women (15 women/1 man). The more often fatal complications are: laryngitis, subcutaneous, emphysema, encephalitis, pernicious malaria, pregnancy complications. It appears highly desirable to extend to adults not yet diseased the immunisation campaign carried out for children.
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PMID:[Complications of measles in adult Africans. Apropos of 95 cases]. 380 54

The clinical and laboratory characteristics of 201 cases of measles and its associations with complications were analyzed during an outbreak of this disease in Mexico City. The complications were hepatitis (45%), bacterial pneumonia (17%), oral candidiasis (13%), upper gastrointestinal tract hemorrhage (13%), epistaxis (8%), encephalitis (4%), subcutaneous emphysema (2%), and hypocalcemic tetany (1%). In a subgroup of 20 consecutive patients hypocalcemia was found in 14 cases (70%), associated with high levels of calcitonin in three cases. An increased lactate dehydrogenase (LDH) was observed in 83% of the patients, showing a significant association with the occurrence of complications (p = 0.04) especially in the patients with values of LDH above 750 IU/mL (odds ratio of 6.4). Two patients died (1% mortality). The young patients with measles can develop serious complications, and an increased level of LDH may be a prognostic indicative of these complications.
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PMID:[Measles in the young adult. Clinical features of 201 cases]. 805 46

Measles is caused by a virus which exclusively affects humans. Erroneously it has been considered benign, although it causes high morbidity and mortality because of the complications it precipitates. The Expanded Program of Immunization estimated that 1.5 million children in the world die every year because of measles. The objective was to analyze the incidence of measles and complicated measles in children who had been admitted to Dr. Robert Reid Cabral Pediatric Clinic, Santo Domingo, Dominican Republic, during the period of January 1991 to January 1992. A total of 311 patients were enrolled with the diagnosis of measles during the 13 months of the study, with an average of 24 cases per month. October and December were the months when most patients presented with measles: respectively, 56 (18%) and 60 (19.4%) patients of the total caseload. Pneumonia was the most frequent complication with 277 cases (87.1%), followed by acute diarrheal disease with 25 cases (8.0%). The most affected was the 1-3 year age group with 143 patients (46.0%). In 135 cases (43.4%) the children with measles had not been vaccinated; only 72 patients (23.3%) had received vaccination. Furthermore, 104 patients (33.3%) did not know their vaccination history. 170 patients (54.7%) were malnourished. During the study period 37 children (11.9%) died in the hospital and 24 of these children (64.9%) died as a result of the complication of pneumonia. Other causes of death were: laryngotracheitis (4), encephalitis (3), subcutaneous emphysema (4), and septicemia (2). This investigation showed that pneumonia is a very grave complication in malnourished children and in children under one year of age.
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PMID:[Incidence of measles with complications]. 1234 61

Two outbreaks of an encephalitis apparently induced by an attenuated live distemper vaccine occurred in a large ferret breeding establishment in New Zealand. Approximately 350 of 6,000 young ferrets 16-22 weeks old died. Many were found dead with no premonitory signs, others showed severe neurological signs. Some with central nervous system (C.N.S.) signs recovered. Pathological examination showed no gross abnormalities except for a few with mild conjunctivitis, rhinitis and lung emphysema. Microscopically there was a moderate to massive non-inflammatory necrosis of hippocampal nerve cell bodies. In those animals which survived for several days with CNS signs there was also a mild to moderately severe non-supportive encephalitis, and in some of these distinct neuronal intranuclear and intracytoplasmic eosinophilic inclusion bodies were seen. Some ferrets also had a bronchiolitis with intracytoplasmic eosinophilic inclusion bodies in bronchiolar epithelium. All these lesions suggest that a distemper like condition was involved. About half of the ferrets also had a mild to severe inflammatory myocardial necrosis.
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PMID:An outbreak of post-vaccinal suspected distemper-like encephalitis in farmed ferrets (Mustela putorius furo). 1603 85