Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0034065 (pulmonary embolism)
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Human Gene/Protein
RNF121 9.1
alpha-1 globin 8.7
HS3ST3A1 8.7
HIP3 8.5
IL28A 8.1
stress-associated endoplasmic reticulum protein 1 8.1
SPAP 7.9
CBLN2 7.9
TSPAN15 7.7
HIVEP1 7.7
endothelial adhesion molecule 1 7.7
SEC61B 7.6
HPF4 7.6
LGM 7.4
factor V Leiden 7.2
IL19 7.0
Antithrombin-III 7.0
engulfment and cell motility 1 7.0
osteocrin 6.9
ZNF263 6.9
SERPINC1 6.8
PROS1 6.7
STAB2 6.7
HS3ST1 6.7
V1-3 6.6
TLT-1 6.5
WARP 6.5
protease-activated receptor 4 6.4
TED 6.4
Cardiac myosin binding protein-C 6.4
IL20 6.4
Coagulation factor XII 6.4
AGGF1 6.3
DNASE1L3 6.2
XDP 6.2
ITGAX 6.2
protein S 6.2
Protein C 6.1
CHAF1A 6.1
PASP 6.1
SMAD9 6.1
factor Xa 6.0
PTE 6.0
ITGAL 6.0
V4-6 6.0
type I protein C 6.0
IL24 5.9
cyclophilin C 5.9
thrombin inhibitor 5.9
beta-fibrinogen 5.9
plasminogen activator, urokinase 5.8
antithrombin 5.8
protein C 5.7
Cardiac troponin I 5.7
SELE 5.7
VWF protein 5.7
tissue plasminogen activator 5.7
POD1 5.6
ARTEMIS 5.6
Cardiac ankyrin repeat protein 5.6
CMPD 5.6
CT-2 5.5
urokinase-type plasminogen activator 5.5
antithrombin III 5.5
TFPI2 5.4
PROS 5.4
CEAP 5.4
Tei 5.4
factor V 5.4
ABO blood type 5.3
ANKRD26 5.3
TRO 5.3
PED 5.2
factor XI 5.2
NNT 5.2
GRIM-19 5.1
thromboxane A2 synthase 5.1
vitamin K epoxide reductase 5.1
TKR 5.1
MMACHC 5.1
more...
Disease
Subacute massive pulmonary embolism 11.1
Saddle PE 11.1
diffuse adenocarcinoma of the stomach 11.1
Thrombotic stroke 11.1
Pulmonary embolism and infarction 11.1
Pulmonary embolism and thrombosis 11.1
pulmonary embolism 11.1
Right ventricular thrombus 11.1
Chronic pulmonary embolism 10.4
Acute massive pulmonary embolism 10.3
Recurrent pulmonary embolism 10.3
Pseudosepsis 10.1
Iliac vein thrombosis 10.1
Anoxic-ischemic encephalopathy 10.1
Acute inferior myocardial infarction 10.1
Thromboembolic pulmonary hypertension 10.1
Axillary vein thrombosis 10.1
Bleeding gastric varices 10.1
Deep vein thrombosis 9.9
Acute right heart failure 9.8
Postoperative deep vein thrombosis 9.8
deep vein thrombosis 9.5
CTPA 9.5
Acute cor pulmonale 9.5
Salmonella paratyphi infection 9.5
Renal thrombosis 9.5
Anastomotic ulcer 9.5
postphlebitic syndrome 9.3
Paradoxical embolism 9.2
DVT 9.1
Vena cava thrombosis 9.1
Systemic fibrinogenolysis 9.1
Factor II mutation 9.1
Pulmonary microemboli 9.1
Right atrial myxoma 8.9
Pulmonary tumor embolism 8.8
Pulmonary thromboembolism 8.8
penis ulcer 8.7
Staphylococcus aureus mediastinitis 8.7
pulmonary infarction 8.7
Intracardiac thrombus 8.6
Superficial phlebitis 8.5
Bronchopulmonary infection 8.5
Acute cerebrovascular disease 8.5
recurrent pituitary tumor 8.5
Occult carcinoma 8.5
Lupus-like syndrome 8.2
Intravascular leiomyomatosis 8.2
Psychogenic cough 8.2
pulmonary vascular disorder 8.2
Phlegmasia cerulea dolens 8.2
Acute right ventricular failure 8.1
Pelvic abscess 8.1
hepatalgia 8.1
Mesenteric infarction 8.1
Bilateral pneumonia 8.1
superficial thrombophlebitis 8.0
Paget-Schroetter syndrome 7.9
DDU 7.9
Tumor embolus 7.9
Chronic constrictive pericarditis 7.8
Heparin-induced thrombocytopenia type II 7.8
LGM 7.8
Protein C deficiency 7.6
vascular obstruction 7.6
retinal vein thrombosis 7.6
Duchenne's disease 7.6
Relative polycythaemia 7.6
stage I Wilms' tumor 7.6
psoitis 7.6
Trousseau's syndrome 7.6
flatback syndrome 7.6
thrombophlebitis 7.6
Protein S deficiency 7.5
hereditary coagulopathy 7.5
Acute respiratory disease 7.5
cor pulmonale 7.4
Chronic Chagas' disease 7.4
Subclavian vein thrombosis 7.4
venous stasis 7.3
more...
Symptom
Varicophlebitis 10.5
Central chest pain 10.1
Chest wall tenderness 9.5
Acute chest pain 8.5
pleuritic chest pain 8.3
CVA tenderness 8.2
lipuria 8.2
Acute dyspnea 8.1
swollen leg 7.8
Platypnea 7.7
joint symptom 7.7
Homan's sign 7.5
Intermittent fever 7.4
musculoskeletal chest pain 7.1
Thoracic pain 6.7
Bladder distention 6.7
toe pain 6.6
rib pain 6.6
shortness of breath 6.3
cold sweats 6.2
tachypnea 6.2
abdominal rigidity 6.1
S3 gallop 6.0
chest pain 5.9
dyspnea 5.9
hemoptysis 5.8
Koplik spots 5.7
facial droop 5.7
Radicular pain 5.6
leg edema 5.6
epigastric distress 5.5
syncope 5.3
non-productive cough 5.2
hypocapnia 5.1
arm weakness 5.1
exertional dyspnea 5.1
nerve root irritation 5.1
atypical chest pain 5.1
orthopnea 5.0
Physical findings 5.0
Sister Mary Joseph's nodule 4.8
leg pain 4.8
chest tightness 4.8
cyanosis 4.7
limb pain 4.7
livedo 4.6
precordial pain 4.6
Neurologic symptoms 4.5
giddiness 4.4
giddiness 4.4
labored breathing 4.3
rales 4.3
localized edema 4.3
right upper quadrant pain 4.2
respiratory distress 4.2
presyncope 4.1
productive cough 4.1
renal colic 4.0
breath holding 3.9
lassitude 3.9
collapse 3.9
persistent cough 3.8
cough 3.8
flank pain 3.8
hemiplegia 3.7
exertional chest pain 3.7
loin pain 3.7
consciousness disturbance 3.7
acid regurgitation 3.7
syncopal episodes 3.7
retching 3.5
catatonia 3.5
irregular bleeding 3.5
bradypnea 3.4
intestinal bleeding 3.4
pedal edema 3.3
Cushingoid 3.3
neuralgia 3.3
Cushingoid 3.2
Spots 3.2
more...
Drug
Clivarine 10.6
Desirudin 9.3
Innohep 9.3
Vascor 8.9
Colistimethate 8.7
Vena 8.5
Vena 8.5
Tenecteplase 8.4
Vascor 8.4
Fondaparinux 8.2
Agrylin 8.1
Alteplase 8.0
Alteplase 7.9
Alteplase 7.9
Lepirudin 7.8
LMWH 7.8
Fragmin 7.7
Ximelagatran 7.6
Apixaban 7.5
Orgaran 7.5
Dalteparin 7.5
Calciparine 7.4
Coumadin 7.3
Streptokinase 7.2
Levophed 7.1
Phenprocoumon 7.1
Activase 7.1
Urokinase 7.0
CYSTEINE 6.9
Diphenhydramine 6.8
Warfarin sodium 6.7
Lovenox 6.6
Bisolvon 6.3
Bucrylate 6.3
Gliadel 6.0
Aescin 6.0
Dihydroergotamine 5.8
Ferrum 5.7
Vitamin K 5.5
Rotigotine 5.4
uPA 5.4
Pantopaque 5.3
Epidoxorubicin 5.3
Gestodene 5.2
Thrombostat 4.9
THA 4.9
Vibramycin 4.8
Argatroban 4.8
Clozaril 4.8
Photofrin 4.7
Cyanoacrylate 4.6
Anagrelide 4.6
Lenalidomide 4.5
Teniposide 4.5
Ovulen 4.5
Syntocinon 4.5
CTA 4.4
Antithrombin III 4.3
CPR 4.2
PE2 4.2
Amrinone 4.2
Mineral oil 4.2
Trandolapril 4.2
Magnevist 4.1
Celebrex 4.1
Iopromide 4.1
Nesiritide 4.1
Oxacillin 4.0
Span 20 4.0
Omniscan 3.9
Arimidex 3.9
Gelfoam 3.9
Ketorolac 3.8
Vitamin K2 3.8
Aprotinin 3.8
Abciximab 3.8
Triad 3.8
Methyldopa 3.7
Panitumumab 3.7
Darbepoetin alfa 3.7
more...
Enzyme
thromboplastin 5.4
tissue plasminogen activator 5.4
urokinase-type plasminogen activator 5.3
LGT 5.2
thrombin-activatable fibrinolysis inhibitor 5.1
ancrod 4.8
APC 4.8
methylenetetrahydrofolate reductase 4.5
methylenetetrahydrofolate reductase 4.5
thrombin 4.1
plasmin 3.9
angiotensin-converting enzyme 2 3.6
thromboxane synthase 3.5
pregnancy-associated plasma protein-A 3.3
CGT 3.3
PPH 3.1
SOR 3.1
Hageman factor 3.1
TGT 3.0
GalT 2.9
asparaginase 2.8
cystathionine beta-synthase 2.7
Omi/HtrA2 2.6
ficin 2.6
CPR 2.6
peptidylarginine deiminase 2.6
FAST 2.5
chymopapain 2.4
chymopapain 2.3
Pla 2.2
STK11 2.2
TAT 2.2
SPT 2.0
CAD 2.0
CAD 1.9
meprin 1.9
CAD 1.9
CCS 1.8
heparinase 1.7
GCA 1.6
SOR 1.6
AGT 1.5
MCS 1.5
TACE 1.4
creatine kinase 1.4
PRA 1.4
PTA 1.3
SPT 1.2
tryptase 1.2
DCF 1.1
ACE 1.1
thymidine phosphorylase 1.0
lysin 1.0
paraoxonase 1.0
CDR 0.8
11beta-hydroxysteroid dehydrogenase 0.7
LPL 0.6
3-hydroxy-3-methylglutaryl coenzyme A reductase 0.5
thyroid peroxidase 0.4
Alternating 0.4
CPT 0.4
MIP 0.4
phosphodiesterase 0.3
paraoxonase 0.3
CPT 0.3
AOR 0.3
endoglycosidase H 0.2
PDE 0.2
enolase 0.2
P-glycoprotein 0.2
BAL 0.1
kallikrein 0.1
guanylate cyclase 0.0
matrix metalloproteinase 9 -0.1
PAH -0.1
CPT -0.1
transglutaminase -0.2
lactate dehydrogenase -0.2
hypoxanthine-guanine phosphoribosyltransferase -0.2
alanine aminotransferase -0.3
more...
Compound
Warfarin 6.5
Tranexamic acid 6.3
Droloxifene 6.2
Heparin 6.2
6-Keto-PGF1a 6.0
Dihydroergotamine 6.0
S 9 6.0
DHCA 5.9
Sulfinpyrazone 5.8
Vitamin K 5.8
TKB 5.6
Poly C 5.6
ETN 5.5
Mestranol 5.2
Desogestrel 5.1
Lithium fluoride 5.1
Toremifene 5.1
Gadodiamide 5.1
Argatroban 4.8
Escin 4.8
Solu-Medrol 4.8
SVC 4.8
Escin 4.8
Dihydralazine 4.8
FDP 4.7
Organon 4.7
Fibrinogen 4.7
Hydromorphone 4.7
Sooner 4.6
HM-3 4.6
Hydroxocobalamin 4.5
NEE 4.5
11-dehydro-thromboxane 4.5
Xenon 4.5
Indigo 4.5
TEP 4.4
Neoprene 4.3
PTS 4.3
BNP 4.3
Zolmitriptan 4.2
DGA 4.2
Dibucaine 4.2
Factor X 4.1
Fibrin 4.1
Oxacillin 4.1
Ketorolac 4.0
1,2-dichloropropane 4.0
Dermatan sulfate 3.9
Surfactin 3.8
Oxacillin 3.8
Plasmin 3.8
Cefpirome 3.7
A 71 3.6
EDAP 3.6
Dihydroxyacetone 3.6
KTS 3.6
BTG 3.6
BTG 3.5
P 2 3.5
DLT 3.5
Homocysteine 3.5
Homocysteine 3.5
DIC 3.5
Pyridoxine 3.5
DTE 3.5
R 2010 3.5
Coumarin 3.5
Thrombin 3.4
MEGA 3.4
Anastrozole 3.4
Hydralazine 3.4
Sulbactam 3.4
CPB 3.4
TGT 3.3
Sildenafil 3.3
Vitamin K1 3.3
F23 3.3
Raloxifene 3.3
Dextran 3.3
Albendazole 3.3
more...