Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034065 (pulmonary embolism)
 14,979 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Treatment of acute embolic and thrombotic occlusions of arteries has to be initiated immediately to save the limb at risk. Surgery has been the treatment of choice for the last decades. Percutaneous mechanical methods for thrombectomy and thrombolysis have evolved and offer alternative treatment options, reducing the peri-operative risk. Percutaneous aspiration thrombembolectomy (PAT), recirculation thrombectomy with the Amplatz device, and different systems for hydrodynamic thrombectomy and thrombolysis (Angiojet, Hydrolyer, S.E.T. catheter) are routinely used for percutaneous thrombectomy and mechanical thrombolysis. These 3.5-10 F systems allow for the rapid removal of a fresh clot from different vascular regions. Complete removal of the clot can be achieved in 19-49%; adjunctive use of other percutaneous methods (thrombolysis and thrombectomy: 60-80%; PTA and atherectomy: 81-100%) results in primary success rates of 67-100% for recanalization of acutely occluded vessels. Primary indications for percutaneous thrombectomy and mechanical thrombolysis are acute occlusions of peripheral arteries and dialysis fistulas; limited experience exists for the treatment of occlusions of the visceral and pelvic vessels. Percutaneous methods seem promising for treatment of acute pulmonary embolism.
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PMID:[Percutaneous thrombectomy and mechanical thrombolysis]. 981 45

We report female patient, age 51, with clinically definitive multiple sclerosis (CDMS) since 1998, who underwent two PTA procedures with stent implantation for CCSVI in 2010. Expanded disability status scale (EDSS) worsened since the procedure from 4.5 to 6. Total number of three stents was implanted (two of them in the right internal jugular vein). In six month time, in 2011, patient was referred for independent examination by computer tomography (CT) phlebography for right-sided neck pain. Dislocation of stents on the right side and thrombosis of left sided stent was found. Conservative approach was used so far. Our short report is showing possible complications of PTA and stenting in jugular veins in so called CCSVI and bringing information about neurological state (EDSS) worsening in a subject. Continuation of stent migration in the future is probable, possibly resulting in pulmonary embolism with fatal risk for the patient. We strongly ask for restriction of PTA procedure in so called CCSVI, which concept was not proven to be relevant to MS.
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PMID:Serious complication of percutaneous angioplasty with stent implantation in so called "chronic cerebrospinal venous insufficiency" in multiple sclerosis patient. 2324 60