Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034065 (pulmonary embolism)
 14,979 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Mycoplasma pneumoniae is a common pathogen for respiratory infection in children, and vascular complication is one of the rarest extrapulmonary complications but with serious consequences. We report a twelve-year-old Chinese female presenting with fever, dry cough, and chest pain aggravated by respiration. She was diagnosed pneumonia due to Mycoplasma pneumoniae and treated with Azithromycin until unexpected tachypnea and swelling in the right lower limb happened. Then ultrasonic examination had revealed two separated thrombi in deep veins before pulmonary embolism was found. Finally she was cured by anticoagulation and immunosuppressive therapy. Though the mechanism of thrombosis after Mycoplasma pneumoniae infection remains unknown, the positive finding in anticardiolipin antibody as well as multi-site thromboses gives a strong hint to immune modulation. Thrombosis should be considered for those who have significantly increased C-reactive protein and positive anticardiolipin antibody after Mycoplasma pneumoniae infection. To our knowledge, this is the first report describing two unattached thrombi in deep veins associated with pulmonary embolism after Mycoplasma pneumonia infection.
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PMID:Two separated thrombi in deep veins associated with pulmonary embolism after Mycoplasma pneumoniae infection: a case in adolescent female. 2683 14

We are describing the case of a 45-year-old female with a past medical history of severe chronic obstructive pulmonary disease (COPD), type 2 diabetes mellitus, and anxiety and with no known allergies to contrast media. The patient presented to her primary care doctor's office with typical symptoms of COPD exacerbation. She was given a five-day course of prednisone (40 mg/day) and Azithromycin and advised to follow up with her pulmonologist. The patient called her pulmonologist's office five days later due to non-relief of symptoms and was advised to get a chest radiograph. The chest X-ray did not show evidence of any acute changes. Her symptoms continued to worsen, and she was advised to get a computerized tomography (CT) of the chest with pulmonary embolism (PE) protocol, where 60 ml of Isovue-370 (Iopamidol - a non-ionic radiocontrast dye) was injected per the PE protocol. She had an unpredictable fatal anaphylactic reaction to non-ionic contrast dyes and suffered a cardiac arrest while getting the scan done.
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PMID:Fatal Anaphylaxis to Contrast a Reality: A Case Report. 3189 Apr 15