Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0034065 (
pulmonary embolism
)
14,979
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Rho
proteins, best known for their regulatory role in actin dynamics, stimulate a variety of processes important in the control of vascular function, including morphogenesis, migration, cell proliferation and adhesion, cell survival, gene expression, vesicle transport and microparticle formation.
Rho
GTPases have been implicated in several pulmonary vascular pathologies. Here we give an overview of the current knowledge of the role of
Rho
GTPases in vascular dysfunction, and pulmonary diseases such as pulmonary hypertension,
pulmonary embolism
, chronic obstructive pulmonary disease, acute lung injury and acute respiratory distress syndrome.
...
PMID:Rho GTPases in pulmonary vascular dysfunction. 2298 42
