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Query: UMLS:C0034065 (pulmonary embolism)
 14,979 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

94 partial interruptions of the inferior vena cava (PIIVC) were carried out in 98 patients between May 1979 and November 1983 with a Mobin-Uddin umbrella filter (58 cases) or a Kim-Ray Greenfield filter (36 cases); one patient who had a double inferior vena cava underwent double PIIVC with a Greenfield filter. The patients (56 women and 42 men) were between 22 and 84 years old (average 60.6 years). Phlebocavography was performed pre-operatively in 93 patients (95 p. 100) and showed thrombus in the IVC (21 cases), common iliac vein (20 cases), ilio-femoral vein (32 cases), femoral vein (15 cases), popliteal and/or sural vein (4 cases); the investigation was considered normal in 1 patient. The diagnosis of pulmonary embolism (PE) was made in 86 patients (87.7 p. 100) on clinical and/or pulmonary scintigraphy and/or angiography data. The main indications for PIIVC were major PE (56 cases) or a threatening venous thrombosis (27 cases); other indications included recurrent PE despite adequate anticoagulation, patients with contra-indications to anti-coagulant therapy and pulmonary hypertension due to thromboembolism; 4 PIIVC were carried out during pulmonary embolectomy on cardiopulmonary bypass. The operative mortality was 3.06 p. 100 (3/98) with a global early mortality of 10.2 p. 100 (10/98); morbidity was 12.2 p. 100 (12/98); there were 5 failures of PIIVC. The long-term outcome was studied in the first 80 cases with a mean follow-up of 18 months (4 to 48 months).(ABSTRACT TRUNCATED AT 250 WORDS)
Arch Mal Coeur Vaiss 1985 Feb
PMID:[Partial interruption of the inferior vena cava by an endovenous filter. Apropos of 98 patients]. 392 Sep 92

A case of double right and left intraventricular thrombosis diagnosed by 2D echocardiography is reported in a 20 year old man with nephrotic syndrome with eosinophilia and hypercoagulability, admitted as an emergency for a staphylococcal septicaemia in shock and anuria. Anticoagulation with heparin did not prevent two episodes of pulmonary embolism. Complete dissolution of the thrombi was obtained by peripheral administration of fibrinolytic therapy (urokinase and plasminogen). The authors discuss the differential diagnosis of echocardiographic appearances of biventricular masses and possible causes of these thrombi are suggested.
Arch Mal Coeur Vaiss 1985 Feb
PMID:[Biventricular thrombosis in nephrotic syndrome with hypercoagulability and hypereosinophilia]. 392 Sep 99

The case of a young man hospitalised for bilateral lower limb deep vein thrombosis is reported. None of the usual causes were found after systematic wide-ranging investigation. The only abnormality on admission was a spontaneous increase in the cephalin-kaolin time to 65 seconds compared to a control time of 40 seconds. Measurements of the clotting factors showed a moderate and isolated deficiency in factor XII (30 p. 100), also present in a brother (50 p. 100) and a sister (42.5 p. 100). Fibrinolytic therapy was administered : an initial course of Streptokinase was followed by extension of a left femoral vein thrombosis and pulmonary embolism. Two courses of Urokinase were given with an eight day interval without significantly improving the venous circulation. This case is an example of thrombogenic disease due to a deficiency of a clotting factor resulting in non-activation of physiological fibrinolysis.
Arch Mal Coeur Vaiss 1985 Mar
PMID:[Thrombophlebitis and pulmonary embolism in congenital factor XII deficiency]. 392 76

Echocardiography may be used in patients presenting with pulmonary embolism to visualise the right heart. The authors report the case of a patient who had recurrent pulmonary embolism. Echocardiography demonstrated a large, mobile thrombus moving freely through the tricuspid valve. There were many cardiac and general contraindications to surgery and fibrinolytic therapy in this particular case. Nevertheless, the mass had totally disappeared on control echocardiography after anticoagulant therapy with heparin. There were no further embolic symptoms. The only change was observed on pulmonary scintigraphy. The patient was discharged a few weeks later on oral anticoagulant therapy. In comparison with previously published results, the outcome of this case was surprisingly good; surgery, which was impossible in our case, would seem to be the treatment of choice.
Arch Mal Coeur Vaiss 1985 Apr
PMID:[Large right intracardiac thrombus cause of recurrent pulmonary embolism. Apropos of a case of favourable course]. 392 91

Thirteen consecutive cases of cardiac hydatic cyst were studied. The cysts were usually multiple, predominantly left ventricular. There were two cases of rupture of left ventricular cysts with systemic embolism, and three ruptures of right ventricular cysts causing pulmonary embolism. The average age of the patients was 31 years: 12 patients lived in regions where hydatid disease was endemic. Other localisations of hydatic disease were found in 7 cases. Two patients were completely asymptomatic. Three patients presented with a tumoral syndrome. The presentation was atypical simulating coronary artery disease in 2 cases, valvular heart disease in 2 cases, pericarditis in 2 cases and bronchopneumonia in 3 cases. The electrocardiogramme showed sinus rhythm in all cases and changes of subepicardial ischaemia in 8 cases and acute cor pulmonale in 3 cases. Chest X-ray showed a localised deformation of the cardiac silhouette in 5 cases and calcification in 4 cases. Direct angiocardiographic signs were present in 2 out of 8 cases; usually there was an indirect image of endocavitary filling defect. The tumour was demonstrated by 2D echocardiography in the three most recent cases. The value of CAT was assessed in the last 2 cases: it was absolutely diagnostic in 1 case of septal localisation. The results were poor in the second case due to the presence of mitral calcification. Twelve patients underwent surgery; there were 3 deaths due to rupture and 1 death before surgery. The clinical presentation of cardiac hydatid disease is very variable and the diagnosis is difficult.(ABSTRACT TRUNCATED AT 250 WORDS)
Arch Mal Coeur Vaiss 1985 Dec
PMID:[Symptomatology of hydatid cyst of the heart. Study of a continuous series of 13 cases and value of x-ray computed tomography]. 393 42

From 1965 to 1981, 27 patients over 35 years of age were operated for isthmic coarctation of the aorta. Surgery consisted of resection and direct suture in 16 cases, implantation of a Dacron prosthesis in 7 cases, isthmoplasty in 1 case, aortotomy-graft in 1 case, insertion of a Dacron tube between the left subclavian artery and the descending thoracic aorta in 1 case; finally, one patient presented with a rare form of coarctation in a double aortic arch and was treated by a bypass from the brachiocephalic trunk to the descending thoracic aorta. Ten patients had associated pathology. This was treated at the same time in 4 cases: closed heart mitral commissurotomy, cardiac plexectomy, section-suture of patent ductus arteriosus, and a resection of aneurysms of four intercostal arteries. A Bjork aortic valve prosthesis had been inserted nine months previously in a women with calcific aortic stenosis. There were 2 deaths (7,4%) in the immediate postoperative woman with calcific aortic stenosis. There were 2 deaths (7,4%) in the immediate postoperative period (one acute pulmonary oedema, one pulmonary embolism). There has been no operative mortality in the last 10 years. Twenty-three of the 25 survivors have been followed-up for an average period of 91,5 months (range 1 to 18 years). Two patients died of cardiovascular causes. Analysis of these results show: that the mortality rate is not prohibitive compared to that of the natural history of the condition (the average survival rate of unoperated patients is 35 years), good secondary results despite frequent technical difficulties, the possibility of residual hypertension (especially in older patients) which responds well to drug therapy.(ABSTRACT TRUNCATED AT 250 WORDS)
Arch Mal Coeur Vaiss 1984 Aug
PMID:[Isthmic coarctation of the aorta: characteristics and results of surgical treatment in subjects surgically-treated after 35 years of age]. 623 25

Numeric angiography is an examination of choice for studying the thoraco-abdominal aorta, whatever the underlying pathological condition, and is often the only angiographic investigation useful and necessary for deciding on therapy in cases of aneurysm. In contrast, results are unsuccessful in approximately 15% of cases when neck vessels are studied. Significant lesions nearly always produce sufficient information for the decision as to therapy to be made. Vascular surgery follow up is an excellent indication for numeric angiography, whatever the surgical technique used or the anatomic site involved. Reliable data can be obtained from pulmonary vessels by the use of this method in patients with pulmonary embolism, arteriovenous malformations, and abnormal venous return.
J Mal Vasc 1984
PMID:[Current applications of numeric angiography in the study of cervico-cerebral vessels, the aorta, pulmonary vessels and following vascular surgery]. 636 22

The association of pericarditis and pulmonary embolism may be the source of diagnostic error and delay in the administration of anticoagulant therapy. Two cases are reported. Pericarditis occurred late in patients with severe, chronic pulmonary embolism with electrocardiographic changes of acute cor pulmonale. Two physiopathological mechanisms for this association have been proposed. The first, haemodynamic, suggests friction between the pericardium and distended right ventricle and pulmonary artery. The second, an immunological hypothesis, compares the association of pericarditis and pulmonary embolism to that of the Dressler syndrome after myocardial infarction. This assimilation would imply the constitution of an anatomical pulmonary infarction. It is not justifiable to accept this pathogenesis on the evidence of transient pulmonary opacities resulting from intra-alveolar haemorrhage or of linear opacities of pulmonary atelectasis secondary to hypocapnic pneumoconstriction which are radiological signs of anatomo-physiological stages of pre-infarction.
Arch Mal Coeur Vaiss 1984 Jun
PMID:[Pericarditis and pulmonary embolism. A difficult differential diagnosis and a confusing association]. 643 34

The results of a multicentre trial (10 centres) of urokinase (UK) extracted from human urine in patients with recent massive pulmonary embolism (PE) are reported. The aim of this trial was to compare the efficacy of two protocols of UK therapy: low dose UK: 2 000 IU/kg/hour (UKl) associated with heparin, against high dose UK: 4 400 IU/kg/hour for 12 hours (UKh) followed by heparin. This randomised single blind trial included patients under 80 years of age. The clinical diagnosis of recent PE (less than 5 days) was confirmed by pulmonary angiography showing over 30% vascular obstruction (Miller index greater than 11). The efficacy of treatment was assessed by the degree of early revascularisation on pulmonary angiography 30 to 48 hours after the start of thrombolytic therapy, as analysed by 4 independent vascular radiologists. A total of 133 patients entered the trial between November 1978 and October 1981: 2 died before receiving treatment, 2 were excluded, 129 patients were retained (67 UKl and 62 UKh). The initial clinical, haemodynamic and angiographic parameters were comparable in the two groups: Miller index; 22.6 +/- 3.7 (UKl) and 22.6 +/- 3.4 (UKh), an average vascularisation defect of 66%. The efficacy of treatment was the same: 26% and 20% respectively. The incidence of haemorrhagic complications was the same in both groups: 24% and 29% respectively, but only 2% of patients had spontaneous severe bleeding.(ABSTRACT TRUNCATED AT 250 WORDS)
Arch Mal Coeur Vaiss 1984 Jul
PMID:[Multicenter study of 2 urokinase protocols in severe pulmonary embolism. Research Group on Urokinase and Pulmonary Embolism]. 643 40

The authors report the case of an active 32 year old man who developed right leg DVT. Before heparinisation, he was discovered to have a low antithrombin III level (biological activity (B) 60%, immunological level (I) 50) and a further inquiry showed the same abnormality in 4 members of the family, leading to a diagnosis of a congenital deficit: a 35 year old sister with a bilateral post-DVT changes had antithrombin III levels of 70% (B) and 45% (I); two nephews, sons of the affected sister: the one aged 5 years was asymptomatic despite antithrombin III levels of 50% (I) and 70% (B); the other had experience DVT at the age of 2 and, on oral anti-vitamin K drugs, had antithrombin III levels of 55% (I) and 67% (B) at the age of 15 years; the patient's brother died at the age of 29 of cerebral vein thrombosis after pulmonary embolism. The recurrence of local signs of DVT after 12 day's heparin therapy with AT III levels (B) of 40%, led to a change in management with infusion of purified AT III concentrate at a dose of 40 U per kg (2 500 U per hour). This induced a rise in AT III activity to over 100% and enabled early introduction of anti-vitamin K therapy. The patient remains asymptomatic after 6 months follow-up. This case illustrates the value of determining AT III activity in all patients who developed DVT without obvious reason.(ABSTRACT TRUNCATED AT 250 WORDS)
Arch Mal Coeur Vaiss 1984 Sep
PMID:[Treatment of deep venous thrombosis in the presence of a congenital antithrombin III deficiency. Apropos of the use of purified concentrates]. 643 83


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