Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0034065 (pulmonary embolism)
 14,979 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A total of 1605 patients with myocardial infarction had been admitted to the district hospital--Sliven for 24 years. The percentage of the deceased out of them is 26.5%. The patients with cardiogenic shock were 166 (10.3%) and 131 of them died (85%). The cardiogenic shock in myocardial infarction reduced its incidence within the 5 years, from 14/4% to 5.3%, and lethality was increased from 75.5 to 91.4%. The males represented 60%. To the age of 60 proved to be 30.1% of the patients. To the age of 45-3.6%; to from 46 to 60-26.5%; from 61 to 75-51.6% and over the age of 75-18%. Angina pectoris was present in 80% in the clinic of the patients with cardiogenic shock in myocardial infarction, with irradiating pain--41%, with asthmatic manifestations--49%, with abdominal manifestations--20% and cerebral manifestations--23%. According to localization the myocardial infarction was grouped as follows: 8.4%--anteroseptal; 17.4%--anterior, 9.6%--massive anterior, 1.8--anterior-apical, 6.4%--anterior lateral, 25.3%--posterior, 9%--posterior-lateral, 5.6%--anterior-posterior, 0.6%--focal and 1% subendocardial. Hypertension proved to be a favourable factor in the development of cardiogenic shock in myocardial infarction in 21.7% as well as diabetes in 15%, rhythm disorders--in 32.2%, pulmonary embolism in 7.9% and decompensation in 14.4%.
 ...
PMID:[Cardiogenic shock in myocardial infarct]. 371 75

Acute dissection of the ascending aorta is a life-threatening disease. Successful management requires close teamwork of internal medical specialist, radiologist and cardiovascular surgeon. The diagnostic and therapeutic approach is reviewed on the basis of 18 of our own cases - 15 men and 3 women aged from 42 to 88 years. Peculiarities of history, pain and ECG give valuable clues to the differentiation of aortic dissection from myocardial infarction and massive pulmonary embolism. As a non-invasive rapidly available diagnostic method echocardiography may yield decisive information about the aortic root and the presence of pericardial effusion. Definite confirmation of diagnosis is accomplished by aortography and/or computed tomography. Blood pressure and aortic flow must be decreased to the lowest level tolerated by the patient to prevent pericardial tamponade or rupture into the mediastinum. The urgency of surgical repair is underlined by a median survival time of 12 hours from onset of symptoms to death with conservative treatment. 7 of our patients were operated on. In 6 cases surgery was performed by means of extracorporeal circulation and the ascending aorta was replaced by a graft. 3 patients survived the operation (2 for over 2 years and three died in the postoperative period due to cerebral and pulmonary complications). In one case with inoperable dissection an axillo-femoral bypass was performed for relief of complete ischaemia of the left lower limb. Postoperatively, maintainance of the patient's blood pressure at the low normal level ist mandatory.
 ...
PMID:[Diagnosis and therapy of supravalvular aortic dissection (type A)--an interdisciplinary challenge]. 372 96

During the period between February 1970 and December 1973, 149 Charnley total hip arthroplasties were performed at UCLA Medical Center. Fifty-seven percent have a follow-up period of at least four years, and 21% have a follow-up period of ten years or more. The peri- and postoperative complication rate was high, with an incidence of 32.6% urinary tract infection (UTI), 4% peroneal nerve palsy, 4% cardiopulmonary, 2% pulmonary embolism, 1.3% myocardial infarction, and 6.0% other. Eleven patients (7.3%) required revision at a mean of 75 months after operation, while an additional three patients were experiencing substantial pain. Clinical improvement after this procedure is similar to that reported by other authors. Survivorship analysis suggests that being young and/or having a diagnosis of osteonecrosis or failed hemiarthroplasty places a patient at a higher risk of failure due to revision surgery or pain.
 ...
PMID:The UCLA Charnley experience: a long-term follow-up study using survival analysis. 376 57

Age has been identified as an independent risk factor for coronary artery bypass grafting (CABG). We evaluated, therefore, the perioperative phase and long-term prognosis of all patients over the age of 64 (n = 80), who had been operated on for coronary heart disease at the University Hospital of Basel/Switzerland between 1979 and 1983. These elderly subjects were compared to 80 patients, 50 to 60 years old at the time of CABG, who were matched for degree of angina pectoris, coronary artery disease, left ventricular ejection fraction, sex and year of operation (matched-pairs analysis). Evaluation of long-term prognosis was based on regular clinical controls and on a questionnaire, sent to the patients in June 1984. During the perioperative phase 3 patients over 64 died versus 0 in the group of patients 50-60 years old. There were more complications in the older group (perioperative myocardial infarction 10 vs. 4, pulmonary embolism 2 vs. 0, cerebro-vascular insult 4 vs. 0). Three vs. one permanent pacemaker had to be implanted for irreversible AV-block. The difference in hospital stay, 21 vs. 19 days, was not significant. The cumulative survival rate was in both groups 95% after one year and 86 vs. 92% 5 years after CABG (difference not significant), despite the fact that significantly more elderly patients have had myocardial infarction prior to CABG. After an average follow-up of 28 months, 72% vs. 60% were without thoracic pain; 63 vs. 49% considered themselves in a good overall condition.(ABSTRACT TRUNCATED AT 250 WORDS)
 ...
PMID:[Aortocoronary bypass operation in the elderly patient: favorable long-term course]. 387 13

31 patients underwent embolectomy for acute embolism of the aortic bifurcation. In most instances paralysis of the extremity (84%) was present, sudden onset of pain (16%) was less common. Neurological disease had been considered in 55%. The heart was source of emboli in 92%. Postoperative complications were mainly due to renal failure (23%) and irreversible limb ischemia (10%) requiring amputation. Mortality after embolism of the bifurcation was 39%. The major cause of death was cardiac failure (58%) followed by renal failure and pulmonary embolism. Even after long delay (4 weeks) successful operation is possible due to adequate collateral circulation supplying the extremity until the blockade is removed.
 ...
PMID:[Symptoms and therapy of aortic bifurcation embolism]. 398 34

This simple study was undertaken because clinical audit revealed that several patients died from sudden massive pulmonary embolism following minor fractures of the pelvis. It is well known that pulmonary embolisms may complicate a major fracture of the pelvis, but so far no study has looked at the incidence of fatal pulmonary embolism after minor fractures. This survey, therefore, is a retrospective survey of 50 consecutive patients with a minor fracture of the pelvis, of whom seven died. In five patients the cause of death was a massive pulmonary embolus, and this occurred despite the fact that all patients were up and about as soon as pain permitted.
 ...
PMID:The mortality of patients with minor fractures of the pelvis. 400 10

Twenty-eight consecutive cases of acute superficial thrombophlebitis of the long saphenous vein above the knee were reviewed concerning presence of asymptomatic deep venous thrombosis and pulmonary embolism and early clinical results after surgical treatment. Contrast phlebography of the ipsilateral leg revealed asymptomatic involvement of major deep veins of the thigh or calf in 4 of 21 examined patients. Perfusion lung scanning and chest radiography demonstrated typical segmental perfusion defects consistent with pulmonary embolism in two of ten examined patients. High ligation and stripping of the phlebitic veins gave prompt cure in 19 patients, though in two who were simultaneously treated with anticoagulants there was troublesome bleeding. Simple high ligation was performed in nine patients without complications, but four of them had protracted phlebitic pain. The results indicated that preoperative phlebography and lung scanning are helpful in detecting associated asymptomatic disorders and for planning therapy in patients with clinically isolated, superficial thrombophlebitis of the long saphenous vein. The treatment of choice is acute high ligation with removal of all phlebitic veins. If anticoagulation is indicated because of concomitant deep venous thrombosis or pulmonary embolism, the initial procedure should preferably be limited to high ligation.
 ...
PMID:Deep venous thrombosis, pulmonary embolism and acute surgery in thrombophlebitis of the long saphenous vein. 401 2

The purpose of this study was to determine the immediate and long-term complications of subclavian vein thrombosis occurring during prolonged catheterization for parenteral nutrition. Ten cases of subclavian vein thrombosis documented by venography were initially treated by catheter removal, systemic heparin, and upper extremity elevation. Although fever was common (N = 9), only three patients had positive blood or catheter cultures and only one patient required antibiotic therapy. Nonfatal pulmonary embolism was suspected by lung scan in only one patient. After a follow-up period of six months to five years (mean two years), no long-term disability, such as arm swelling or pain, was identified. We conclude that immediate and late sequelae of catheter-associated subclavian vein thrombosis are minimized by prompt removal of the catheter, systemic administration of heparin to prevent clot propagation and embolism, and arm elevation to reduce early upper extremity edema.
 ...
PMID:Subclavian vein thrombosis during prolonged catheterization for parenteral nutrition: early management and long-term follow-up. 640 84

The problem of treatment of a combination of failed hip arthroplasty secondary to resorption, osteoporosis, osteolysis, or fracture is unsolved. Twenty-seven such complicated hips, including four with previous infection, were treated by a femoral prosthesis driven into an intramedullary nail. The goal of stability, allowing immediate mobilization, was attained in virtually all patients. The oldest was 84 years of age and the mean age was 69.3 years. In the early postoperative period, one patient died of pulmonary embolism and one of myocardial infarction. Two infections were treated 25 and 11 months after implantation; these patients were free from pain and showed no signs of loosening of the implant. The mean time in the hospital for the infected patients was 60 days and for the noninfected patients was 23 days. Among 14 patients who were observed for at least ten months after surgery, freedom from pain was achieved in eight, significant alleviation of pain in five, and slight improvement in one. Five patients also became completely free from dependence on walking aids; seven used one or two canes. Two patients were dependent on crutches. Discrepancy in the length of the lower limbs was noted in seven patients. Six patients showed 1 cm shortening and one patient 2 cm. In six patients the Trendelenburg sign was negative, and in only three patients was it clearly positive. The mean Harris Hip Score in 14 patients observed for more than ten months after surgery was 82. Intramedullary nailing combined with a femoral component in total hip arthroplasties, where defects or fractures of the femur have occurred, give good fixation of the implant components and a satisfactory functional result.
 ...
PMID:Hip arthroplasty with an extended femoral stem for salvage procedures. 649 25

We have reviewed our experience with the treatment of 250 patients with deep vein thrombosis diagnosed by contrast venography. The level of thrombosis was recorded according to the anatomic level to which it extended. A third of the patients had cancer, and the most common clinical findings were swelling and pain. The risk of the development of pulmonary embolism, based on the anatomic level of initial deep vein thrombosis, revealed the following: 12 of 115 patients (10 percent) with level I (calf) deep vein thrombosis developed pulmonary embolism, as did 2 of 27 patients (7 percent) with level II (popliteal) disease, 5 of 60 (8 percent) with level III (thigh) disease, 1 of 19 patients (5 percent) with level IV (groin) disease, and 2 of 26 patients (8 percent) with level V (iliac) disease. Based on our favorable experience with heparin we believe that heparin is the treatment of choice for deep vein thrombosis regardless of the anatomic level. The incidence of pulmonary embolism does not appear to be influenced significantly by the level of the deep vein thrombosis.
 ...
PMID:Therapeutic and clinical course of deep vein thrombosis. 663 64


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>