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Query: UMLS:C0034065 (pulmonary embolism)
 14,979 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A typical case of advanced obstructive cardiomyopathy in a young subject was revealed by Streptococcal mitral valve endocarditis and was diagnosed by one and two dimensional echocardiography, which revealed a pedunculated vegetation on the large mitral valve and rupture of the chordae of the small mitral valve. This was complicated by biventricular heart failure, peripheral arterial embolism in the leg due to migration of the vegetation which disappeared on the repeat echocardiography and pulmonary embolism with arterial clot emboli due to heparin-induced thrombocytopenia. This condition resolved without requiring cardiac surgery. Patients with obstructive cardiomyopathy should be treated routinely with prophylactic antibiotics, particularly when dental treatment is required. Echocardiography has become an essential examination in the diagnosis of this disease and its complications, especially in cases with infectious endocarditis.
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PMID:[Diagnosis and echocardiographic course of infectious endocarditis in obstructive cardiomyopathy]. 404 Mar 48

The main goal of the cardiopulmonary resuscitation is good neurological outcome. The primary ischaemic insult initiates a multitude of coagulation and inflammatory cascades resulting in cytotoxic brain oedema, necrosis and apoptosis. Thrombolytic agents may have experimentally and clinically significant beneficial effects in non-traumatic cardiac arrest. Prospective clinical trials show that thrombolytic therapy combined with heparin is feasible, safe and effective during resuscitation. We demonstrate three cases of successful systemic thrombolysis during in hospital CPR in cancer patients. Two patients were successfully resuscitated from cardiac arrest with streptase bolus (500.000 IU) and infusion (100,000/hr). One patient with pulmonary embolism and gynecological bleeding were treated with bolus (10,000 IU) and infusion of heparin (1,000 IU/hr) and successfully resuscitated. We observed a very good neurological outcome in all 3 cases following rescue thrombolysis and standard CPR. Two patients were discharged from hospital in good neurological outcome. One patient died on ICU on 10th day due to myocardial re-infarction and biventricular failure. Systemic thrombolysis is safe and effective treatment modality during resuscitative efforts even in cancer patients. In oncological patients with dissemination and/or bleeding heparin therapy should be considered due to better clinical control. (Ref. 17.)
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PMID:Rescue systemic thrombolysis during cardiopulmonary resuscitation. 1251

Cases with thrombi in multiple cardiac chambers are rare. We report an extremely rare case in which thrombi were formed in all four cardiac chambers at the same time. A 55-year-old man presented with biventricular failure and liver dysfunction. A 12-lead ECG and an echocardiogram revealed an old anteroseptal myocardial infarction with aneurysm formation and atrial flutter. A transesophageal echocardiogram and a CT of the chest revealed thrombi in the right and left atrial appendage, right ventricular apex and left ventricular aneurysm. Pulmonary emboli were also identified. Stasis of the blood due to ventricular dysfunction and atrial flutter was considered to be responsible. The patient died of multiorgan failure due to circulatory failure.
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PMID:Thrombi in all four cardiac chambers in a patient with an old anteroseptal myocardial infarction and atrial flutter. 2542 54