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Query: UMLS:C0034065 (pulmonary embolism)
 14,979 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Twelve cases of pulmonary embolism were found among 4,896 autopsies during 18 years in Ramathibodi hospital. This gives an incidence of 0.24 per 100 necropsies. Deep vein thrombosis occurred in two of the twelve cases and was not the main cause of pulmonary embolism in this series.
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PMID:Autopsy proven cases of pulmonary thromboembolism: 18-year study at Ramathibodi Hospital. 276 21

Deep vein thrombosis and pulmonary embolism are known complications in neurosurgical patients, but prophylactic treatment is not commonly used in neurosurgical units. However the incidence of thromboembolism is comparable to general surgical patients, when reliable tests are applied. This retrospective study examines the clinical incidence of thromboembolism in 1378 neurosurgical patients. A thromboembolic complication is found in 2.6% of the patients, 1.4% of them shows pulmonary embolism. Clinical incidence seems to be small, but adjustment of heparin treatment is always difficult in neurosurgical patients and it is often insufficient. Partial inferior vena cava interruption is indicated in nearly half of the patients. Prospective studies are necessary to appreciate the incidence of deep vein thrombosis in neurosurgical patients with a reliable test. The efficiency and security of the prophylactic methods must be evaluated.
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PMID:[Clinical incidence of thromboembolism in neurosurgery]. 280 58

Deep vein thrombosis (DVT) detectable by the 99mTechnetium-labeled plasmin test developed in 13 (37%) of 35 sequentially studied patients, all above 40 years, undergoing elective major abdominal surgery. Ten of the 13 patients with DVT had an abnormal pulmonary perfusion scintigram, suggesting pulmonary embolism (PE), but only three had clinical evidence of thrombotic disease.
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PMID:Distinction by radioisotope technique of a subgroup with increased thrombophilic potential among patients submitted to major abdominal surgery. 295 36

Deep vein thrombosis of the upper extremity is rare. While its pathogenesis is not always evident, it often occurs in connection with tumors, thoracic outlet syndrome or intravenous catheter therapy. Acute thrombosis of the subclavian vein usually is a clinical diagnosis, but in doubtful cases diagnostic tests such as Doppler ultrasound and/or plethysmography may be useful. If necessary, verification of subclavian vein thrombosis can be done by phlebography. Considering the incidence of thromboembolic complications such as pulmonary embolism, anticoagulation is indicated in all cases of acute thrombosis. Under standard conservative treatment residual symptoms following the venous occlusion are few and the prognosis is favorable. Therefore, invasive treatment such as thrombectomy or thrombolysis should be considered only in special cases.
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PMID:[Deep venous thrombosis of the upper extremities]. 305 67

The problem of thromboembolic complication in patients undergoing surgery for colorectal malignancies has been evaluated based on data from the literature and own experiences. One problem is the few studies dealing exclusively with this group of patients or presenting separate data on these patients. Deep vein thrombosis is somewhat more common than that seen after other types of abdominal surgery. No difference between patients operated on for colonic or rectal cancer have been found. The number of fatal or contributory pulmonary emboli is higher than the average number among other operated patients. Low dose heparin, low molecular weight heparin and mechanical methods, especially when combined with heparin or dextran, reduce the frequency of deep vein thrombosis. Fatal pulmonary embolism can effectively be prevented by low dose heparin with or without dihydroergotamine or by dextran.
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PMID:Thromboembolic problems in colorectal cancer surgery. 305 61

Deep vein thrombosis (DVT) and pulmonary embolism (PE) are both characterized by unreliable clinical diagnosis and significant long-term sequelae. In patients with DVT, popliteal valvular insufficiency is associated with increased risk for postphlebitic syndrome. Current data show thrombolytic therapy to be more effective than anticoagulation for DVT, accomplishing significant or complete clearing of the deep venous system in nearly half of all patients treated. Results of investigation show lytic therapy to also be more effective than heparin in treatment of PE, both in terms of acute resolution and long-term function.
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PMID:Deep vein thrombosis and pulmonary embolism: clinical presentation and pathophysiologic consequences. 313 Oct 10

Disturbances of blood coagulation often occur in various malignancies. Deep vein thrombosis or pulmonary embolism often precedes the manifestation of a solid tumour. Chemotherapy, irradiation, surgery, infections are the triggering factors of a blood clotting abnormality. In the present paper the plasmatic clotting factors and platelet functions were studied in patient with solid tumour and with lymphoma. The most characteristic findings were: ethanol positivity, increased fibrinogen level, decreased euglobulin lysis, impairment of platelet functions. In solid tumours the signs of hypercoagulability were more expressed, in non-Hodgkin lymphomas the platelet functions were decreased. These data were in good correlation with data in the literature: in tumours and lymphomas an activation of blood clotting and platelets can be observed.
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PMID:Haemostatic alterations in lymphomas and tumours. 367 Oct 21

A prospective and randomized study of 100 patients with fracture of the femoral neck was carried out. The aim was to compare the thromboembolic prophylactic effect of dextran 70 and a sulphated polysaccharide, PZ 68. Deep vein thrombosis was diagnosed using the 125I-fibrinogen test and phlebography, and pulmonary embolism with a perfusion and ventilation scan. The number of thromboses and emboli did not differ significantly between the two groups. However, there was a general tendency for predominance of thrombosis on the operated side. Six patients were excluded in the PZ 68 group because of major haemorrhage.
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PMID:Prophylaxis of deep vein thrombosis in patients with fracture of the femoral neck: a prospective comparison between dextran and a sulphated polysaccharide. 617 50

A prospective study of antithrombin III, determined by electroimmunochemical assay or an amidolytical method, was carried out with special reference to thromboembolism after total hip replacement. Two hundred and seven patients were randomly allocated to thromboembolic prophylaxis with dextran 70 or low dose heparin combined with dihydroergotamine. Deep vein thrombosis determined by phlebography of the operated leg or pulmonary embolism diagnosed with perfusion/ventilation scintigraphy developed in 51% of the total material and did not differ significantly between the two groups of prophylaxis or between patients with a preoperative At III below normal and those with a normal value. The correlation between the two assay methods for At III was 0.61. An initial, postoperative decrease in At III was noted with a parallel fall in hematocrit and fibrinogen, later followed by an increase of the plasma proteins. It is concluded that the immediate postoperative decrease of At III is mostly due to hemodilution.
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PMID:Pre- and postoperative levels of antithrombin III with special reference to thromboembolism after total hip replacement. 619 14

A prospective study was performed in 120 patients undergoing total hip arthroplasty. The patients were randomly allocated to four groups. The first two groups had nitroprusside-induced hypotensive anesthesia with either a fixed combination of sodium heparin and dihydroergotamine mesylate (HDHE) or dextran 70. The other two groups had normotensive halothane anesthesia with either HDHE or preoperative hemodilution with dextran 70. Hypotensive anesthesia reduced surgical bleeding. Blood loss was increased in patients undergoing preoperative hemodilution as compared to thromboprophylaxis with HDHE, whereas no difference was found between conventional administration of dextran and HDHE. Deep vein thrombosis, diagnosed with ascending phlebography of the operated leg, was registered in 48% of the patients. There was no difference between the techniques of anesthesia and thromboprophylaxis. Pulmonary embolism, studied with perfusion-ventilation scintigraphy, was diagnosed in 19% of the patients. No significant difference was found between hypotensive and normotensive anesthesia, or between thromboprophylaxis with conventional dextran and HDHE. There was a lower incidence of pulmonary embolism in patients with HDHE and normotensive anesthesia. Major wound hematomas were noted postoperatively in 12% of the patients receiving HDHE, whereas no major hematomas developed following dextran prophylaxis. No anaphylactic reaction was noted from dextran 70, using hapten-dextran prophylaxis.
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PMID:Hypotensive anesthesia, thromboprophylaxis and postoperative thromboembolism in total hip arthroplasty. 620 42


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