Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034065 (pulmonary embolism)
 14,979 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Between 1980 and 1996, 16 patients (10 women) with pathologically confirmed insulinomas were operated on; they represents a median of 0.9 per year and 1.1 per cent from the total of pancreatic tumors. Median age was 47.2 (+/- 22.8) years old (range 23-68). Insulinomas occurred with following frequency in: head--2 patients, body and tail--11 patients and diffuse forms (nesidioblastomas)--3 patients. The specific clinical forms only with tumoral syndrome (without hypoglycemic manifestations) and one was an intraoperative discovery. In the case of the four patients two presented with splenic-portal hypertension +/- upper digestive haemorrhages and the other two only tumoral syndrome. The surgical approach was: the midline (ten), uni- or bilateral subcostal (five), and other incisions one. There were performed tumor exeresis through: enucleation (three), segmentary pancreatectomies (two), spleno-left-pancreatectomies (nine) and the extension of an anterior pancreatectomy (one). In one case biopsy alone was done. The tumors were not intraoperatively identified in three cases (blind left spleno-pancreatectomies). The malignancy index was 4/16 (25 per cent). Postoperative mortality rate was 12.5 per cent (two patients: one acute necrotizing pancreatitis and one pulmonary embolism).
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PMID:[Insulinomas--nesidioblastomas. Clinical experience]. 945 52

BNM, a 40 years Hindu male presented with history of intermittent fainting attacks and had increase in body weight for last 2 years. He used to take a lot of sweets to recover from the attact. His body wht was 100 kg. His fasting blood sugar was 50 mg/dl and insulin glucose (I/G) ratio was 0.6. CT scan of abdomen showed one solitary tumour in the body of pancreas near its tail. Laparotomy was done. The tumour was found to be a benign insulinoma on microscopic examination. Though the postoperative period was uneventful but he succumbed probably due to pulmonary embolism.
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PMID:Insulinoma-a case report. 1457 22