Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0034063 (pulmonary edema)
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Human Gene/Protein
tumor necrosis factor type 1 receptor associated protein 11.5
OR2A14 10.5
WW-domain binding protein 2 10.5
Cellular tumor antigen p53 10.0
EIF4ENIF1 10.0
SGK196 9.5
claudin 18 9.2
ANKRD31 9.0
MPHOSPH6 9.0
RACK7 8.7
HECTD2 8.7
Mitogen-activated protein kinase 1 8.5
NIMA-related kinase 7 8.5
TDFA 8.5
IFN-alpha 5 8.1
RNA editase 8.1
ZNF208 8.0
TG1019 8.0
ACYP2 7.8
GLVR1 7.8
ABHD4 7.8
ABIN2 7.8
endosomal adaptor protein 7.7
DOK3 7.7
Claudin-18 7.6
E-type ATPase 7.5
CFHR4 7.5
Receptor for advanced glycation end-products 7.5
TBC1D7 7.5
plexin C1 7.5
PAWP 7.3
neuropeptide S receptor 1 7.3
cytochrome P450 2J2 7.3
MT-ND3 7.0
TLT-1 7.0
ITSN 7.0
SCARB2 6.9
Myosin light-chain kinase 6.9
suprabasin 6.9
Hsp70 interacting protein 6.9
AF5q31 6.8
DHRS3 6.8
amiloride-sensitive sodium channel 6.8
NAF1 6.7
GEFH1 6.6
RSK3 6.6
KCNJ12 6.6
AQP5 6.6
Na,K-ATPase alpha subunit 6.6
HECT E3 ubiquitin ligase 6.6
EPLIN 6.6
CerS4 6.6
semaphorin 7A 6.6
serine/threonine kinase 2 6.5
ENaC 6.5
Nova-1 6.5
nucleotide-binding oligomerization domain containing 2 6.5
BAG2 6.4
GHRH-R 6.4
hematopoietic prostaglandin D synthase 6.4
CHIP28 6.4
p190RhoGAP 6.4
Nedd4-2 6.3
coronin-1 6.3
DC10 6.3
skin tryptase 6.3
ubiquitin-like protein Nedd8 6.3
Asef 6.3
Urokinase plasminogen activator 6.2
MT-ND5 6.2
CerS1 6.2
corin 6.1
mitochondrial aldehyde dehydrogenase 2 6.1
regulator of telomere length 6.1
EC-SOD 6.1
Keratinocyte growth factor 6.1
MT-ND2 6.1
AQP3 protein 6.1
ATPase mRNA 6.0
PDE7 6.0
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Disease
Subacute mountain sickness 11.5
Acute subendocardial infarction 11.5
Low output heart failure 11.5
pulmonary edema 11.5
Negative pressure pulmonary edema 11.2
Reexpansion pulmonary edema 11.0
Postoperative pulmonary edema 11.0
High altitude pulmonary edema 10.9
Flash pulmonary edema 10.8
Cardiogenic pulmonary edema 10.6
Hemorrhagic pulmonary edema 10.5
Chronic left ventricular failure 10.5
Pulmonary microemboli 10.5
Acute congestive heart failure 10.5
Capillary hyperpermeability 10.5
hypertension with LV hypertrophy 10.5
Renal atherosclerosis 10.5
Eggshell calcification 10.5
Vulval edema 10.5
Interstitial myocarditis 10.5
Neurogenic pulmonary edema 10.4
Silo Filler's Disease 10.1
Engraftment syndrome 10.0
Toxic pulmonary oedema 10.0
Pulmonary immaturity 10.0
Microbial substitution 10.0
uremic pneumonitis 9.7
Pulmonary veno-occlusive disease 9.7
acute pulmonary edema 9.6
Sympathicotonia 9.5
Clostridium perfringens type D enterotoxaemia 9.5
Transfusion-related acute lung injury 9.5
congestive atelectasis 9.4
Acute respiratory distress 9.3
Progressive pulmonary hypertension 9.2
successful suicide attempt 9.2
Clostridium welchii infection 9.2
Toxic myocarditis 9.2
Silent myocardial infarction 9.2
Hemoglobinuric nephrosis 9.2
Diuretic abuse 9.2
Atherosclerotic renal artery stenosis 9.2
Bilateral renal artery stenosis 9.1
mountain sickness 9.1
Acute left ventricular failure 9.1
Transfusion related acute lung injury (TRALI) 9.1
Irukandji syndrome 9.0
Chemical pneumonitis 9.0
Influenza viral infections 9.0
senile psychosis 9.0
Brain compression 9.0
Marble spleen disease 9.0
Compensated metabolic acidosis 9.0
Acute mountain sickness 9.0
Acute respiratory insufficiency 8.7
erythrocyanosis 8.7
Chronic respiratory acidosis 8.7
laryngospasm 8.7
Post-infectious glomerulonephritis 8.5
Irresponsibility 8.5
High output heart failure 8.5
Drug-induced hyperkalemia 8.5
Bilateral pneumonia 8.5
Mitral obstruction 8.5
Hantavirus pulmonary syndrome 8.4
Moderate depression 8.4
Hypertensive crisis 8.2
adult respiratory distress syndrome 8.2
Pulmonary air embolism 8.2
stage II gastric cancer 8.2
Transient left ventricular apical ballooning syndrome 8.1
herpangina 8.1
Shoshin beriberi 8.1
Acute mitral regurgitation 8.0
fluid overload 7.8
Meconium aspiration syndrome 7.8
left ventricular failure 7.8
Transmural myocardial infarction 7.7
Neonatal anoxia 7.7
Acute respiratory acidosis 7.7
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Symptom
Moist rales 10.5
Expiratory dyspnea 10.0
skin tenderness 9.5
S3 gallop 8.5
swollen penis 8.2
Chills and fever 8.2
decreased bowel sounds 8.1
Acute edema 8.0
rales 7.8
Diaphragmatic weakness 7.3
Dribbling 7.3
Bladder distention 7.2
Respiratory abnormalities 7.2
orthopnea 7.1
respiratory distress 6.8
Lung hyperinflation 6.7
cold sweats 6.7
tachypnea 6.7
Acute dyspnea 6.5
retrosternal discomfort 6.4
localized edema 6.4
oliguria 6.4
labored breathing 6.1
pedal edema 6.1
Acute chest pain 6.0
hyperoxia 6.0
epigastric distress 6.0
bradypnea 5.9
dyspnea 5.9
cyanosis 5.9
abnormal breathing 5.8
Severe diarrhea 5.7
shortness of breath 5.7
Organ failure 5.6
hypoproteinemia 5.6
hypocapnia 5.5
hemoptysis 5.5
staggering gait 5.4
lassitude 5.4
Pain at rest 5.2
leg edema 5.1
frequent urination 5.1
precordial pain 5.1
onychomadesis 5.1
non-productive cough 5.0
Crawling 5.0
giddiness 4.9
respiratory problem 4.9
tonic-clonic seizure 4.9
giddiness 4.9
chest tightness 4.8
monoplegia 4.8
generalized erythema 4.7
hypercapnia 4.7
prostration 4.6
postnasal drip 4.5
chest pain 4.5
cough 4.5
Signs and Symptoms 4.4
excessive sweating 4.4
leg cramps 4.3
exertional dyspnea 4.3
lethargy 4.3
collapse 4.3
physical exhaustion 4.2
rigors 4.2
stridor 4.2
syncopal episodes 4.1
CSR 4.1
throat irritation 4.1
ketonuria 4.0
chills 3.9
regurgitation 3.9
generalized pain 3.9
hypothermia 3.9
consciousness disturbance 3.9
pallor 3.8
emaciation 3.8
asynergy 3.8
nasal discharge 3.7
more...
Drug
Carfentanil citrate 9.5
Halidor 9.2
Ultane 9.0
Selectol 8.7
Plasmanate 8.2
Quinine sulfate 7.8
Orthoclone OKT3 7.5
Securopen 7.5
Ambroxol hydrochloride 7.5
Piriprost 7.5
CYSTEINE 7.4
Terbutaline sulfate 7.3
Gelfilm 7.2
Dazoxiben 7.1
Fentanyl citrate 7.1
Dyazide 7.0
Sivelestat 7.0
Etizolam 7.0
Talwin 6.8
Ulinastatin 6.7
Meconium 6.6
Fenoterol 6.6
Irofulven 6.6
Diamox 6.6
Imagent 6.5
Dibenzyline 6.5
Torasemide 6.4
Hydroxyethylstarch 6.4
E5564 6.4
Gabexate mesilate 6.3
Ambien 6.3
Pulmozyme 6.2
Talwin 6.2
Survanta 6.1
7-Nitroindazole 6.1
Antivenin 6.0
Pralidoxime 5.9
Creosote 5.9
Rokitamycin 5.8
Beraprost 5.8
Ergometrine 5.7
Protamine sulfate 5.6
Lasalocid 5.6
Chlorothiazide 5.5
Talc 5.4
Jujube 5.4
Narcan 5.3
CPFX 5.3
Methylprednisolone 5.3
Clozaril 5.3
Lepirudin 5.2
Rolipram 5.1
Magnesium sulfate 5.1
Budesonide 5.1
Muse 5.1
Ciclesonide 5.0
Emodin 5.0
Hydrochlorothiazide 4.9
LAAM 4.9
Quinine, 4.9
Sodium acetate 4.9
Clove 4.9
Basiliximab 4.8
Basiliximab 4.8
Tapentadol 4.7
Sesamol 4.7
Emodin 4.7
Solcoseryl 4.7
Mineral oil 4.7
Sodium nitroprusside 4.6
Nesiritide 4.5
Roflumilast 4.5
Roflumilast 4.5
Bumetanide 4.4
Bosentan 4.4
Bosentan 4.4
Febuxostat 4.4
Florfenicol 4.4
Chlorate 4.4
Rocuronium 4.4
more...
Enzyme
okinaxobin II 10.5
ceramide synthetase 6.9
PAF acetyltransferase 6.2
PAF acetyltransferase 5.3
BAL 5.2
thromboxane synthase 5.0
PPH 4.6
PHT 4.6
dimethylarginine dimethylaminohydrolase 4.3
MIP 4.2
neutrophil elastase 4.1
Pla 4.0
meprin 4.0
homogentisate 1,2-dioxygenase 4.0
phosphatidylinositol-4,5-bisphosphate 3-kinase 3.9
PIP kinase 3.9
ricin 3.8
lysophospholipase D 3.8
ancrod 3.7
lipoxygenase 3.7
2A protease 3.7
sphingomyelin synthase 3.7
C3b inactivator 3.5
xanthine oxidase 3.5
elastase 3.3
peroxidase 3.3
cysteine synthase 3.3
neutral sphingomyelinase 3.2
type III procollagen 3.1
caspase-11 3.1
caspase-11 3.1
ACE 3.0
sphingosine kinase 3.0
SNO 3.0
phosphodiesterase 3.0
myosin light chain kinase 3.0
creatine kinase 2.9
superoxide dismutase 2.8
CPN 2.8
choline kinase 2.8
sulfite oxidase 2.7
prolyl hydroxylase 2.7
lactate dehydrogenase 2.7
NO synthase 2.7
sulfite oxidase 2.7
interstitial collagenase 2.7
3C protease 2.6
CPR 2.5
flavin-containing monooxygenase 2.4
tryptase 2.4
renin 2.3
CCS 2.3
thrombin 2.3
MTD 2.3
cathepsin G 2.3
prostaglandin synthetase 2.3
PDE 2.3
xanthine dehydrogenase 2.3
p-nitrophenylphosphatase 2.3
branching enzyme 2.2
endothelin-converting enzyme 2.2
ATPase 2.2
CPM 2.1
heme oxygenase 2.1
E-2 2.1
gamma-glutamylcysteine synthetase 2.1
NOS 2.0
ADH 2.0
CEP 2.0
PCP 2.0
kallikrein 2.0
SST 2.0
triphosphatase 2.0
apyrase 2.0
AGT 2.0
glutathione peroxidase 1.9
phospholipase A2 1.9
MDH 1.9
aspartate aminotransferase 1.9
catalase 1.9
more...
Compound
Jesaconitine 11.5
Perilla ketone 10.4
4-chloro-2-isopropyl-5-methylphenol 9.5
alpha-Ethyltryptamine 9.2
disialosyl galactosyl globoside 8.7
Fraxin 8.4
Ritodrine hydrochloride 7.8
Isochlorogenic acid 7.5
Propylhexedrine 7.5
4-isopropyl-3-methylphenol 7.5
Mometasone 7.5
4-Ipomeanol 7.4
Ricinine 7.4
Ruscogenin 7.4
3-methylindole 7.4
Chlorphentermine 7.3
Nitroethane 7.2
selenic acid 7.1
Anisodamine 7.1
selenic acid 7.1
selenic acid 7.1
Narciclasine 7.0
Veratrine 6.9
3,5-dimethoxyphenol 6.8
Desmosine 6.8
4-Thiouridine 6.8
Lanatoside C 6.8
Ritodrine 6.8
Hexachloroethane 6.8
Pinitol 6.6
Strophanthin 6.5
Metaproterenol 6.5
Patchouli alcohol 6.5
Minipress 6.5
HMDI 6.4
C6H8O7 6.4
AA861 6.4
Dibenzyline 6.4
Ergotamine tartrate 6.4
Costunolide 6.4
Sphinganine 6.3
Cresol 6.3
ReSe2 6.3
Sclareol 6.3
Terbutaline 6.2
Dexpanthenol 6.2
p-Bromophenacyl bromide 6.1
beta-Lapachone 6.1
Monocrotaline 6.0
Dioscin 6.0
Dioscin 6.0
Acetazolamide 6.0
Quine 5.9
Pralidoxime 5.9
Methazolamide 5.9
Meclofenamate 5.8
Pristimerin 5.8
Moricizine 5.8
Pinitol 5.8
Pristimerin 5.8
Pristimerin 5.8
Pristimerin 5.8
Chymostatin 5.8
Granulin 5.8
Prone 5.7
Ethyl pyruvate 5.7
Benzamil 5.7
FB2 5.7
Nalorphine 5.6
DPPD 5.6
Acacetin 5.5
beta-Naphthoflavone 5.5
fluoroacetic acid 5.4
Methylprednisolone 5.4
Rimantadine 5.4
Oleic acid 5.4
Ergonovine 5.4
Bantu 5.3
Nerolidol 5.3
Lobeline 5.3
more...