Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034063 (pulmonary edema)
 10,665 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Chest radiographs taken under ideal conditions and reviewed by a radiologist experienced in looking for pulmonary oedema are an accurate technique for detecting early oedema, differentiating between congestion and oedema, monitoring the increases in oedema up to the stage of alveolar flooding and in determining the effects of CPPV on an oedematous lung. However, ideal conditions do not exist in the I.C.U. Our radiologist had the advantage of a fast exposure, a normal film for comparison in the sequence and only one lesion, conditions unlikely to occur in the I.C.U. It becomes apparent that it is important to obtain the best possible image in these complicated patients. Films in the erect position, for vascular distribution, as well as fast exposures with a high MAS factor give the sharp detail required to best assess lung changes. Serial studies of the chest are a requirement of the I.C.U. patient and it is helpful if comparable films are obtained by using a fixed target-to-film distance in association with the short exposure factors. If this care is taken, chest radiographs are the most accurate non-invasive technique for detecting pulmonary oedema.
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PMID:Radiological changes in controlled hypervolaemic pulmonary oedema in dogs. 109 33

The pathophysiology of functional deficiency of pulmonary surfactant in the neonatal respiratory disorders represented by MAS, hemorrhagic lung edema and ARDS was discussed. The removal of inhibitor(s) is the cardinal procedure for MAS and the lavage with surfactant solution seems to be promising. In case of replacement therapy, we should consider using a different dose compared to the one used in RDS due to lung immaturity, in order to optimize results.
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PMID:Functional pulmonary surfactant deficiency and neonatal respiratory disorders. 1009 35

Meconium aspiration syndrome is a serious neonatal disease with complex pathophysiology. With respect to the contribution of meconium-induced lung edema, inflammation and vasoconstriction on the course of the disease, glucocorticoids are increasingly used in the treatment of MAS despite the fact that principal questions on the choice of GCs derivative, mode of delivery and dosing have not been answered yet. To bring a complex insight into the topic, this article reviews the pathomechanisms of MAS, mechanisms of action of GCs, as well as the advantages and disadvantages of GCs administration in experimental models and newborns with MAS.
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PMID:Glucocorticoids in the treatment of neonatal meconium aspiration syndrome. 2146 22