Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0034063 (pulmonary edema)
 10,665 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pulmonary edema, although infrequently encountered, may cause death in severe cases of PIH. The mechanisms that account for edema in these instances are unclear. With a transducer-membrane system to directly measure serum COP, 22 patients with PIH were compared to 23 normal pregnant patients at term. In the PIH group the antepartum and postpartum COP values were significantly lower (17.9 and 13.7 mm Hg, respectively) than comparable values for the control group (22.0 and 17.2 mm Hg, respectively). Two patients in the PIH group in whom the antepartum COP values were 13.1 and 14.7 mm Hg exhibited clinical and radiographic evidence of pulmonary edema. Pulmonary artery wedge pressure (PAW) recorded in one patient with pulmonary edema was only moderately elevated to 18 mm Hg. We believe that serial COP determinations combined with pulmonary artery pressure monitoring may be helpful to guide fluid therapy in critically ill patients with PIH.
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PMID:Studies of colloid osmotic pressure in pregnancy-induced hypertension. 48 18

Pregnancy-induced hypertension is a disorder of unknown etiology unique to pregnant women. Classic clinical manifestations include hypertension, proteinuria, and edema. Early recognition and proper management of this disease may serve to avoid serious maternal complications. Ultimate maternal treatment depends on delivery of the fetus and placenta. Advanced stages of this disease result in multi-organ system dysfunction that may be life-threatening to the mother and her fetus. Such maternal complications of PIH include severe hypertension, oliguria or anuria, HELLP syndrome, eclamptic seizures, liver rupture, pulmonary edema, cerebral edema, and abruptio placentae. A multidisciplinary approach of the critical care team often will effect a reduction in maternal morbidity and mortality.
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PMID:Management of severe preeclampsia and eclampsia. 174 3