Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0034063 (pulmonary edema)
 10,665 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We reported a case of 64 year-old female patient of pulmonary tuberculosis associated with ARDS during corticosteroid treatment of Rheumatoid Arthritis. On admission her chief complaints were fever, fatigue and dyspnea. A chest roentgenogram showed diffuse alveolar infiltration consistent with pulmonary edema. Arterial blood gas studies showed severe hypoxemia. We clinically diagnosed so-called ARDS. Smears of sputum for acid fast bacilli were negative, but transbronchial lung brushing by bronchofiberscope revealed many acid fast bacilli. Intensive therapy with anti-tuberculosis drugs (INH, RFP, SM), high dose corticosteroid (methylprednisolone) therapy and mechanical ventilation was started. During the following 2 weeks, the PaO2 rose gradually and the alveolar infiltration on the chest roentgenogram disappeared. The experience of this case to emphasized the importance of suspecting this condition because pulmonary tuberculosis is a potentially curable cause of ARDS and it should also be emphasized that the good treatment effect could be expected with combined use of high dose corticosteroid and mechanical ventilation.
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PMID:[A case of pulmonary tuberculosis associated with adult respiratory distress syndrome during corticosteroid treatment of rheumatoid arthritis]. 221 15

A 62-year-old man had been treated with INH, RFP, EB, and PZA for pulmonary tuberculosis. Six months after completing the treatment, he was admitted because of low grade fever and abdominal distension. His abdominal radiograph and CT showed ascites, which showed elevated ADA. He was diagnosed as tuberculous peritonitis, and treated with INH, RFP, and EB. Three days after starting treatment, the ascites abruptly disappeared, followed by bilateral pleural effusion and pulmonary edema. He was found to develop ARDS. His pleural fluid was removed and treated with steroid pulse therapy. In spite of improvement of dyspnea, general status gradually deteriorated and he died following two months and a half treatment. Ascites causing a marked increase in abdominal pressure in a patient with tuberculosis peritonitis might move into the thoracic cavity with an unknown mechanism, and the removal of ascites might be needed to prevent this phenomenon.
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PMID:[A case of tuberculous peritonitis showing a rapid increase of bilateral pleural effusion]. 1583 58