Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0034063 (pulmonary edema)
 10,665 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pulmonary oedema occurred following relief of an acute upper airway obstruction in an infant with Pierre-Robin syndrome undergoing cleft palate repair. We anticipate an increased prevalence of this phenomenon in view of the present trend for early palatal repair, and would advocate the routine use of a nasopharyngeal airway after operation in infants with severe micrognathia.
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PMID:Pulmonary oedema following relief of upper airway obstruction in the Pierre-Robin syndrome: a consequence of early palatal repair? 154 Apr 73

A male infant presenting with multiple anomalies including a midline cleft palate, anasarca, hepatomegaly, pulmonary edema, agenesis of the corpus collosum, and complex congential cardiac anomalies was found to have mosaicism for an additional chromosome that appeared (following GTG-banding and FISH) to be a monocentric isochromosome of the short arm of chromosome 8 (46,XY/47,XY, +i(8p)). Nine other cases of mosaicism for an additional i(8p) were reviewed. Considerable phenotypic variation was noted. Consistent features were identified including agenesis of the corpus callosum, cardiac malformations, and minor facial dysmorphology. The phenotype of these patients partially overlaps those of trisomy 8 and trisomy 8p. By studying additional individuals with this condition, mosaic tetrasomy 8p may emerge as a recognizable clinical phenotype.
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PMID:Mosaic "tetrasomy" 8p: case report and review of the literature. 859 71

Non cardiogenic pulmonary edema is a rare complication of upper airway obstruction. Its etiology is controversial, but probably can be explained by the Starling's law, when the large negative intrathoracic pressure generated exceeds the intravascular and interstitial pressures, shifting fluids from capillaries to interstitium and alveoli. In addition, alteration of capillary permeability potentiates fluid migration. We present herein, a case of non cardiogenic pulmonary edema following relief of upper airway obstruction in a 14 years old girl underwent surgical repair of cleft palate. Cardiogenic pulmonary edema could be excluded by a normal CVP, wedge pressure and four chamber echocardiography. The edema fluid: plasma protein ratio greater than 0.7 can indicate an increased capillary permeability. Mendelson's syndrome could be ruled out by the rapid improvement seen and the soft clinical course.
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PMID:Non cardiogenic pulmonary edema as consequence of upper airway obstruction. 1523 54