Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0033774 (pruritus)
14,546 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 942
Itch 622
IgE 545
She 322
scratch 288
alkaline phosphatase 259
mast cell 257
cytokine 214
substance P 170
Mol 131
opioid receptor 127
ubiquitin 111
IL-4 110
calcineurin 108
collagen 106
albumin 104
interferon 103
chronic renal failure 95
TRPV1 85
IL-31 85
IL-13 75
CD4 75
TNF 66
E3 ubiquitin ligase 64
parathyroid hormone 64
nerve growth factor 62
aspartate aminotransferase 61
IL-6 60
calcitonin 60
alanine aminotransferase 59
lymphoid 58
TRPA1 58
insulin 58
Pol 57
tumor necrosis factor 56
gastrin-releasing peptide 56
thymic stromal lymphopoietin 55
ICP 54
hemoglobin 51
IgA 49
epidermal growth factor receptor 47
histamine H1 receptor 44
ASA 44
Rec 43
reserved 43
CO2 43
phosphodiesterase 43
IFN 41
filaggrin 41
IL-5 39
tyrosine kinase 38
lamp 36
IL-10 36
bradykinin 35
gut 35
CD8 35
gastrin-releasing peptide receptor 34
hairless 34
IL-17 34
Alagille syndrome 34
p53 33
transient receptor potential vanilloid 1 33
serum albumin 32
Pseudomonas 32
AST 32
JAK2 32
proteasome 31
ubiquitin ligase 30
MRI 30
kappa opioid receptor 28
Janus kinase 28
ABCB11 27
5-hydroxytryptamine 27
erythropoietin 27
cyclooxygenase 27
ankyrin 1 27
IL-33 26
gamma-glutamyl transpeptidase 26
prothrombin 26
BP180 26
more...
Disease
pruritus 14546
atopic dermatitis 1504
rash 849
dermatitis 789
skin disease 751
urticaria 746
cholestasis 702
cancer 699
psoriasis 555
depression 494
eczema 490
asthma 435
allergic rhinitis 417
tumor 393
Contact Dermatitis 339
liver disease 293
primary biliary cirrhosis 268
eosinophilia 233
infestation 227
cirrhosis 213
diabetes 212
scabies 210
anaphylaxis 200
cold 194
prurigo 191
rhinitis 189
xerosis 179
hepatitis 173
cholangitis 169
carcinoma 163
lymphadenopathy 159
conjunctivitis 149
anemia 148
plaque 147
allergic conjunctivitis 142
acne 140
hypertension 139
chronic renal failure 137
HIV 136
lichen planus 133
lymphoma 127
pemphigoid 122
chronic pain 120
melanoma 120
primary sclerosing cholangitis 116
seborrheic dermatitis 114
chronic urticaria 114
erythroderma 113
renal disease 112
infectious diseases 111
vaginal discharge 110
fungal infection 108
lichen sclerosus 103
hyperkeratosis 100
onchocerciasis 100
renal failure 96
lice 89
vasculitis 88
mastocytosis 88
food allergy 87
ICP 86
hay fever 86
hyperparathyroidism 83
piles 82
conjunctiva 82
vitiligo 82
candidiasis 81
metastases 81
hepatitis C 81
polycythemia vera 78
AIDS 78
vagina 78
malaria 77
vaginitis 76
squamous cell carcinoma 74
Hodgkin's disease 74
chronic liver disease 71
mycosis fungoides 71
leukemia 70
thrombocytopenia 70
more...
Symptom
pain 2566
erythema 1092
nausea 704
analgesia 559
vomiting 526
fatigue 454
sneezing 416
headache 391
anesthesia 360
diarrhea 356
discomfort 294
discomfort 290
rhinorrhea 248
abdominal pain 240
cough 202
nausea and vomiting 193
dry skin 189
Welt 185
dizziness 179
dyspnea 165
sleepiness 164
flushing 154
nasal congestion 140
weakness 140
anorexia 122
constipation 117
paresthesia 104
insomnia 103
arthralgia 102
tingling 101
Ill 96
splenomegaly 83
wheezing 82
photophobia 76
dysuria 75
myalgia 73
chills 71
hepatomegaly 71
numbness 70
bone pain 67
back pain 65
skin irritation 60
asthenia 52
shortness of breath 48
seizures 47
acute pain 45
nasal discharge 40
lethargy 40
night sweats 38
agitation 38
blurred vision 36
hepatosplenomegaly 36
collapse 35
tense 34
abdominal discomfort 32
chest pain 31
cancer pain 28
dry eye 28
skin damage 28
thinning 28
tinnitus 27
ataxia 27
otalgia 27
pallor 27
syncope 27
dysesthesia 26
vertigo 25
respiratory distress 24
chest tightness 23
sore throat 23
Wind 21
Sedation 21
dark urine 21
epigastric pain 20
hoarseness 20
low back pain 18
angina 17
ENT 17
Generalized pruritus 17
skin pain 16
more...
Drug
Dermatol 2251
Histamine 141
Asthma 139
Tacrolimus 48
Dial 36
Allergen 35
CSF 29
Pimecrolimus 24
Fentanyl 24
Nephron 24
IL-2 24
Nephron 22
Imiquimod 21
IFN-gamma 21
PTH 20
ENT 19
Gabapentin 19
niacin 17
vitamin E 16
Loratadine 14
Bupivacaine 13
Acyclovir 13
Olopatadine hydrochloride 13
Fluticasone propionate 12
lysine 12
Ketotifen 12
Prednisolone 12
Mectizan 11
Ketoconazole 11
Omalizumab 11
Pregabalin 11
ampicillin 10
Ebastine 10
nitroglycerin 10
Retinoic acid 10
Prograf 10
Prednisone 10
Norplant 9
Clobetasol propionate 9
Cardiovasc 9
lactose 9
Gefitinib 9
Levocabastine 9
EE2 8
Diphenhydramine 8
Aloe 8
Ipilimumab 8
Fluconazole 8
Auranofin 8
OTC 7
Portal 7
Albumin 7
caffeine 7
Leaf 7
OTC 7
ADR 7
Adapalene 7
MAP 7
Gel 7
IPM 7
HCH 7
Fosphenytoin 7
Sorafenib 7
Norplant 6
Aprepitant 6
Nalfurafine hydrochloride 6
Spectrum 6
Ketorolac 6
Isotretinoin 6
Biopolymers 6
Infliximab 6
Cetuximab 6
Calcipotriol 6
CPO 6
Captopril 6
Erlotinib 6
Indomethacin 6
Infliximab 6
Patanol 6
Nedocromil sodium 6
more...
Enzyme
alkaline phosphatase 259
alanine aminotransferase 129
calcineurin 109
ERK 94
aspartate aminotransferase 92
gamma-glutamyl transpeptidase 92
focal adhesion kinase 76
trypsin 69
mitogen-activated protein kinase 60
tryptase 58
phosphodiesterase 43
proteasome 34
AST 32
peroxidase 18
protein kinase C 17
protein kinase 15
lactate dehydrogenase 15
plasmin 14
acetylcholinesterase 14
cholinesterase 13
superoxide dismutase 12
papain 12
phospholipase C 12
histidine decarboxylase 11
kallikrein 11
diamine oxidase 11
ACE 10
creatine kinase 10
MEK 10
phospholipase A2 9
collagenase 9
KLK7 8
hexosaminidase 8
luciferase 8
lysozyme 8
lipase 7
ACS 7
cathepsin S 7
transpeptidase 7
ornithine transcarbamylase 7
ubiquitin-protein ligase 7
catalase 6
transglutaminase 6
P-glycoprotein 6
tyrosine hydroxylase 6
ATPase 6
CYP3A4 6
chymase 6
reverse transcriptase 5
urease 5
thrombin 5
thromboplastin 5
ferrochelatase 5
urease 5
tyrosinase 5
Rex 5
adenylate cyclase 5
NOS 5
monoamine oxidase 4
xanthine oxidase 4
chymopapain 4
NO synthase 4
type III procollagen 4
CD10 4
granzyme B 4
prostate-specific antigen 4
pyruvate dehydrogenase 4
caspase-8 4
chymopapain 4
APC 4
DCF 3
asparaginase 3
sulfatase 3
thyroid peroxidase 3
leucine aminopeptidase 3
lysophospholipase D 3
glutathione S-transferase 3
endonuclease 3
beta-lactamase 3
lipoxygenase 3
more...
Compound
Clin 1272
Dec 952
water 372
calcium 272
sodium 199
Histamine 141
DNA 128
phosphate 111
creatinine 99
oxygen 95
His 80
urea 78
glucose 75
sulfate 70
Ursodeoxycholic acid 69
salt 69
potassium 67
TNF 66
5-HT 65
CO2 64
vitamin D 59
zinc 53
ethanol 52
ASA 52
acetate 52
nickel 51
FK506 50
Morphine 46
nitrogen 44
hydroxide 43
iron 43
nitric oxide 41
phosphorus 40
Ivermectin 37
Dial 36
galactose 35
Capsaicin 35
aluminum 34
salicylic acid 33
alanine 33
copper 32
acetone 31
tryptophan 31
nitrate 30
Substance P 30
Pac 28
KOH 27
iodine 27
glutamate 26
Cetirizine 26
Chloroquine 25
retinoic acid 25
serine 25
Chloroquine 25
arginine 25
Cyclosporine 24
tyrosine 24
Rifampicin 22
PGE2 21
formaldehyde 21
cysteine 20
hyaluronic acid 20
Estrogen 19
formaldehyde 19
6-12 19
silver 18
ATP 18
benzyl benzoate 18
Naltrexone 18
Cbl 18
GPT 18
sodium chloride 17
PGD2 17
adenosylmethionine 17
Azelastine 17
NH2 17
Cardiol 17
Vancomycin 16
lysine 16
PEG 16
more...