Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0033774 (
pruritus
)
14,546
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
942
Itch
622
IgE
545
She
322
scratch
288
alkaline phosphatase
259
mast cell
257
cytokine
214
substance P
170
Mol
131
opioid receptor
127
ubiquitin
111
IL-4
110
calcineurin
108
collagen
106
albumin
104
interferon
103
chronic renal failure
95
TRPV1
85
IL-31
85
IL-13
75
CD4
75
TNF
66
E3 ubiquitin ligase
64
parathyroid hormone
64
nerve growth factor
62
aspartate aminotransferase
61
IL-6
60
calcitonin
60
alanine aminotransferase
59
lymphoid
58
TRPA1
58
insulin
58
Pol
57
tumor necrosis factor
56
gastrin-releasing peptide
56
thymic stromal lymphopoietin
55
ICP
54
hemoglobin
51
IgA
49
epidermal growth factor receptor
47
histamine H1 receptor
44
ASA
44
Rec
43
reserved
43
CO2
43
phosphodiesterase
43
IFN
41
filaggrin
41
IL-5
39
tyrosine kinase
38
lamp
36
IL-10
36
bradykinin
35
gut
35
CD8
35
gastrin-releasing peptide receptor
34
hairless
34
IL-17
34
Alagille syndrome
34
p53
33
transient receptor potential vanilloid 1
33
serum albumin
32
Pseudomonas
32
AST
32
JAK2
32
proteasome
31
ubiquitin ligase
30
MRI
30
kappa opioid receptor
28
Janus kinase
28
ABCB11
27
5-hydroxytryptamine
27
erythropoietin
27
cyclooxygenase
27
ankyrin 1
27
IL-33
26
gamma-glutamyl transpeptidase
26
prothrombin
26
BP180
26
more...
Disease
pruritus
14546
atopic dermatitis
1504
rash
849
dermatitis
789
skin disease
751
urticaria
746
cholestasis
702
cancer
699
psoriasis
555
depression
494
eczema
490
asthma
435
allergic rhinitis
417
tumor
393
Contact Dermatitis
339
liver disease
293
primary biliary cirrhosis
268
eosinophilia
233
infestation
227
cirrhosis
213
diabetes
212
scabies
210
anaphylaxis
200
cold
194
prurigo
191
rhinitis
189
xerosis
179
hepatitis
173
cholangitis
169
carcinoma
163
lymphadenopathy
159
conjunctivitis
149
anemia
148
plaque
147
allergic conjunctivitis
142
acne
140
hypertension
139
chronic renal failure
137
HIV
136
lichen planus
133
lymphoma
127
pemphigoid
122
chronic pain
120
melanoma
120
primary sclerosing cholangitis
116
seborrheic dermatitis
114
chronic urticaria
114
erythroderma
113
renal disease
112
infectious diseases
111
vaginal discharge
110
fungal infection
108
lichen sclerosus
103
hyperkeratosis
100
onchocerciasis
100
renal failure
96
lice
89
vasculitis
88
mastocytosis
88
food allergy
87
ICP
86
hay fever
86
hyperparathyroidism
83
piles
82
conjunctiva
82
vitiligo
82
candidiasis
81
metastases
81
hepatitis C
81
polycythemia vera
78
AIDS
78
vagina
78
malaria
77
vaginitis
76
squamous cell carcinoma
74
Hodgkin's disease
74
chronic liver disease
71
mycosis fungoides
71
leukemia
70
thrombocytopenia
70
more...
Symptom
pain
2566
erythema
1092
nausea
704
analgesia
559
vomiting
526
fatigue
454
sneezing
416
headache
391
anesthesia
360
diarrhea
356
discomfort
294
discomfort
290
rhinorrhea
248
abdominal pain
240
cough
202
nausea and vomiting
193
dry skin
189
Welt
185
dizziness
179
dyspnea
165
sleepiness
164
flushing
154
nasal congestion
140
weakness
140
anorexia
122
constipation
117
paresthesia
104
insomnia
103
arthralgia
102
tingling
101
Ill
96
splenomegaly
83
wheezing
82
photophobia
76
dysuria
75
myalgia
73
chills
71
hepatomegaly
71
numbness
70
bone pain
67
back pain
65
skin irritation
60
asthenia
52
shortness of breath
48
seizures
47
acute pain
45
nasal discharge
40
lethargy
40
night sweats
38
agitation
38
blurred vision
36
hepatosplenomegaly
36
collapse
35
tense
34
abdominal discomfort
32
chest pain
31
cancer pain
28
dry eye
28
skin damage
28
thinning
28
tinnitus
27
ataxia
27
otalgia
27
pallor
27
syncope
27
dysesthesia
26
vertigo
25
respiratory distress
24
chest tightness
23
sore throat
23
Wind
21
Sedation
21
dark urine
21
epigastric pain
20
hoarseness
20
low back pain
18
angina
17
ENT
17
Generalized pruritus
17
skin pain
16
more...
Drug
Dermatol
2251
Histamine
141
Asthma
139
Tacrolimus
48
Dial
36
Allergen
35
CSF
29
Pimecrolimus
24
Fentanyl
24
Nephron
24
IL-2
24
Nephron
22
Imiquimod
21
IFN-gamma
21
PTH
20
ENT
19
Gabapentin
19
niacin
17
vitamin E
16
Loratadine
14
Bupivacaine
13
Acyclovir
13
Olopatadine hydrochloride
13
Fluticasone propionate
12
lysine
12
Ketotifen
12
Prednisolone
12
Mectizan
11
Ketoconazole
11
Omalizumab
11
Pregabalin
11
ampicillin
10
Ebastine
10
nitroglycerin
10
Retinoic acid
10
Prograf
10
Prednisone
10
Norplant
9
Clobetasol propionate
9
Cardiovasc
9
lactose
9
Gefitinib
9
Levocabastine
9
EE2
8
Diphenhydramine
8
Aloe
8
Ipilimumab
8
Fluconazole
8
Auranofin
8
OTC
7
Portal
7
Albumin
7
caffeine
7
Leaf
7
OTC
7
ADR
7
Adapalene
7
MAP
7
Gel
7
IPM
7
HCH
7
Fosphenytoin
7
Sorafenib
7
Norplant
6
Aprepitant
6
Nalfurafine hydrochloride
6
Spectrum
6
Ketorolac
6
Isotretinoin
6
Biopolymers
6
Infliximab
6
Cetuximab
6
Calcipotriol
6
CPO
6
Captopril
6
Erlotinib
6
Indomethacin
6
Infliximab
6
Patanol
6
Nedocromil sodium
6
more...
Enzyme
alkaline phosphatase
259
alanine aminotransferase
129
calcineurin
109
ERK
94
aspartate aminotransferase
92
gamma-glutamyl transpeptidase
92
focal adhesion kinase
76
trypsin
69
mitogen-activated protein kinase
60
tryptase
58
phosphodiesterase
43
proteasome
34
AST
32
peroxidase
18
protein kinase C
17
protein kinase
15
lactate dehydrogenase
15
plasmin
14
acetylcholinesterase
14
cholinesterase
13
superoxide dismutase
12
papain
12
phospholipase C
12
histidine decarboxylase
11
kallikrein
11
diamine oxidase
11
ACE
10
creatine kinase
10
MEK
10
phospholipase A2
9
collagenase
9
KLK7
8
hexosaminidase
8
luciferase
8
lysozyme
8
lipase
7
ACS
7
cathepsin S
7
transpeptidase
7
ornithine transcarbamylase
7
ubiquitin-protein ligase
7
catalase
6
transglutaminase
6
P-glycoprotein
6
tyrosine hydroxylase
6
ATPase
6
CYP3A4
6
chymase
6
reverse transcriptase
5
urease
5
thrombin
5
thromboplastin
5
ferrochelatase
5
urease
5
tyrosinase
5
Rex
5
adenylate cyclase
5
NOS
5
monoamine oxidase
4
xanthine oxidase
4
chymopapain
4
NO synthase
4
type III procollagen
4
CD10
4
granzyme B
4
prostate-specific antigen
4
pyruvate dehydrogenase
4
caspase-8
4
chymopapain
4
APC
4
DCF
3
asparaginase
3
sulfatase
3
thyroid peroxidase
3
leucine aminopeptidase
3
lysophospholipase D
3
glutathione S-transferase
3
endonuclease
3
beta-lactamase
3
lipoxygenase
3
more...
Compound
Clin
1272
Dec
952
water
372
calcium
272
sodium
199
Histamine
141
DNA
128
phosphate
111
creatinine
99
oxygen
95
His
80
urea
78
glucose
75
sulfate
70
Ursodeoxycholic acid
69
salt
69
potassium
67
TNF
66
5-HT
65
CO2
64
vitamin D
59
zinc
53
ethanol
52
ASA
52
acetate
52
nickel
51
FK506
50
Morphine
46
nitrogen
44
hydroxide
43
iron
43
nitric oxide
41
phosphorus
40
Ivermectin
37
Dial
36
galactose
35
Capsaicin
35
aluminum
34
salicylic acid
33
alanine
33
copper
32
acetone
31
tryptophan
31
nitrate
30
Substance P
30
Pac
28
KOH
27
iodine
27
glutamate
26
Cetirizine
26
Chloroquine
25
retinoic acid
25
serine
25
Chloroquine
25
arginine
25
Cyclosporine
24
tyrosine
24
Rifampicin
22
PGE2
21
formaldehyde
21
cysteine
20
hyaluronic acid
20
Estrogen
19
formaldehyde
19
6-12
19
silver
18
ATP
18
benzyl benzoate
18
Naltrexone
18
Cbl
18
GPT
18
sodium chloride
17
PGD2
17
adenosylmethionine
17
Azelastine
17
NH2
17
Cardiol
17
Vancomycin
16
lysine
16
PEG
16
more...