Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0033774 (pruritus)
 14,546 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

People with HIV/AIDS often develop hypersensitivity to certain drugs, particularly Nevirapine (Viramune). This drug causes reactions, including a rash, in more than 33 percent of people who use it. A life-threatening rash, known as Stevens-Johnson syndrome, occurs in 1 percent of patients using Nevirapine. Doctors in France conducted a desensitization program on three subjects who developed rash or hives, high fever, swollen eyes and painful muscles after starting the medication. Patients were given gradually increasing doses of Nevirapine and monitored for reactions. Two subjects developed mild itching, which cleared up after receiving Allegra; the third subject did not respond to the treatment.
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PMID:Desensitization to Nevirapine. 1136 44

Allergic Rhinitis is typically characterized by sneezing, rhinorrhoea, nasal obstruction, nasal, conjunctival & pharyngeal itching and lacrimation all occurring in a temporal relation to allergen exposure. The peak incidence of this disease occurs in childhood and adolescence, with most of the cases belonging to the atopic category.There is a high incidence of patients of allergic rhinitis attending the outdoor sections of Ajmal Khan Tibbiya College Hospital. Many of them are dissatisfied with conventional anti-histaminic drugs. An open study was carried out on 20 such patients aged between 15 to 50 years to evaluate the clinical efficacy of a unani pharmacopeal preparation [Itrifal ustukhudoos] added with cloves [qaranfal]. Preliminary clinical study showed promising results. The study is into the next phase in which a comparative double-blind trial is being conducted with this combination and Allegra (Fexofenadine hydrochloride).
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PMID:Evaluation of a combination of a unani pharmacopeal preparation (itrifal ustukhudoos) with cloves (qaranfal) in allergic rhinitis - a preliminary clinical study. 2255 3