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Query: UMLS:C0033774 (pruritus)
 14,546 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Symptoms as an important sign of the effects of methyl bromide were studied in 56 male workers (37 currently exposed and 19 previously exposed) in a methyl bromide factory. The workers were 18 to 62 yr of age (mean age: 41) and were exposed from 1 to 25 yr (mean: 7 yr). They were compared to 56 age-matched referents with a standardized questionnaire. The results of pairwise comparison of the symptoms of the age-matched pairs of exposed and referent subjects showed that the occurrence of dizziness, numbness, paresthesia and weakness of extremities, nightmares, fatigue and dry and scaly skin was statistically significantly higher among the workers than among the referents. When the symptoms during the work shift (acute symptoms) were compared, irritation symptoms such as itching, bullae or reddish swollen hands and runny noses with nasal irritation were reported significantly more often in the exposed groups. The correlation of the symptoms among the exposed workers suggested that chronic symptoms are closely related to acute irritation symptoms and exposure duration. The results suggest that symptom inquiry is useful for detecting the possible effects of exposure to methyl bromide.
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PMID:Symptoms among workers with long-term exposure to methyl bromide. An epidemiological study. 165 69

In a collaborative study with small-animal veterinary surgeons, dogs with fur and skin conditions were treated with biotin (approximately 5 mg biotin/10 kg body weight/day) for 3 to 5 weeks. In total 119 cases could be treated which were reported to show symptoms such as dull coat, brittle hair, loss of hair, scaly skin, pruritus or dermatitis. Cases requiring other treatments with e.g. glucocorticoids, were excluded from the study. In 60% of the cases all symptoms were reported to be cured after the biotin treatment and in a further 31% an improvement was noted; in only 9% no effect was recorded. All breeds responded but to a variable extent: e.g. in Poodles the response was lower (no response in 6 out of 11 cases) than in Alsatians where all improved and 14 out of 29 were completely cured. The results confirm the favourable effect of biotin for treatment of fur and skin conditions in dogs.
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PMID:Clinical study on the effect of biotin on skin conditions in dogs. 260 24

A diagnosis of food allergy was made in eighteen dogs after they were fed on a hypoallergenic diet of lambs meat and rice. The skin complaints returned after the dogs were challenged with the original food. A commercial hypoallergenic diet was given once the skin complaints had disappeared after refeeding of the lamb and rice diet. Six of the eighteen dogs developed skin complaints (pruritus, scaly skin, and erythema) on the commercial diet.
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PMID:[Prospective study of a commercial hypoallergenic diet in 18 dogs with food allergy]. 797 45

Eczema cannot be cured, but much can be done both to prevent and alleviate its symptoms in children. Emollients--available as bath oils, soap substitutes and moisturisers--have a vital role in treating dry, scaly skin and tackling the scratch/itch cycle. They should be used daily, and can be administered alongside topical steroids and other treatments.
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PMID:Know how treatment for childhood eczema. 983 64

A retrospective study of patients admitted to an Orthopaedic Trauma Unit over an 8-year period requiring fasciotomies, of either upper or lower limb, to reduce the risk of compartment syndrome was performed. Sixty patients were studied, of which 49 had an underlying fracture. The long-term morbidity of the wounds was studied. Ongoing symptoms such as pain related to the wound occurred in six patients (10%) and altered sensation within the margins of the wound occurred in 46 patients (77%). Examination revealed 24 patients (40%) with dry scaly skin, 20 patients (33%) with pruritus, 18 patients (30%) with discoloured wounds, 15 patients (25%) with swollen limbs, 16 patients (26%) with tethered scars, eight patients (13%) with recurrent ulceration, eight patients (13%) with muscle herniation and four patients (7%) with tethered tendons. The appearance of the scars affected patients such that 14 (23%) kept the wound covered, 17 (28%) changed hobbies and seven (12%) changed occupation. This study reveals a significant morbidity associated with fasciotomy wounds. In light of these findings, further consideration should be given to techniques that reduce both the symptoms and examination findings mentioned above and the aesthetic insult to the affected limb.
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PMID:Long-term sequelae of fasciotomy wounds. 1109 Mar 26

Itchy skin rashes, pruritus, are common in people with HIV infection. Pruritus is associated with HIV-induced immunosuppression, opportunistic infections, cancer, or other illness. Most conditions can be successfully treated when diagnosed. The most common causes of itchy skin include scabies and other insect bites, inflamed hair follicles, drug reactions, scaly skin disorders, and photosensitivity dermatitis. Each of these conditions is described and treatments are suggested.
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PMID:Itchy skin in HIV. 1136 52

To see if evening primrose oil (EPO) could be more effective in a certain type of atopic dermatitis, we administered EPO to 14 atopic dermatitis patients characterized by itchy dry scaly skin. Furthermore, we measured serum levels of gamma-interferon (IFN-gamma) and IgE in addition to the clinical severity before and after the treatment to find out whether the treatment effect of EPO is related with an immunological mechanism. After the treatment, the extent of the skin lesions and the pruritus were markedly reduced in all patients. While serum IFN-gamma levels were significantly increased (p < 0.01) after the treatment up to those of the normal control group, serum IgE levels showed a significant decrease (p < 0.05), failing to normalize completely. We concluded that EPO could be highly effective in the treatment of a grossly noninflammatory type of atopic dermatitis. The restoration of serum IFN-gamma levels indicates that EPO might exert its effect through the modulation of the immunological mechanism involving IFN-gamma.
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PMID:The therapeutic effect of evening primrose oil in atopic dermatitis patients with dry scaly skin lesions is associated with the normalization of serum gamma-interferon levels. 1180 54

Moisturizing creams have beneficial effects in the treatment of dry, scaly skin, but they may induce adverse skin reactions. In a randomized double-blind study, 197 patients with atopic dermatitis were treated with one of the following: a new moisturizing cream with 20% glycerin, its cream base without glycerin as placebo, or a cream with 4% urea and 4% sodium chloride. The patients were asked to apply the cream at least once daily for 30 days. Adverse skin reactions and changes in skin dryness were assessed by the patient and a dermatologist. Adverse skin reactions such as smarting (a sharp local superficial sensation) were felt significantly less among patients using the 20% glycerin cream compared with the urea-saline cream, because 10% of the patients judged the smarting as severe or moderate when using glycerin cream, whereas 24% did so using urea-saline cream (p < 0.0006). No differences were found regarding skin reactions such as stinging, itching and dryness/irritation. The study showed equal effects on skin dryness as judged by the patients and the dermatologist. In conclusion, a glycerin containing cream appears to be a suitable alternative to urea/sodium chloride in the treatment of atopic dry skin.
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PMID:A double-blind study comparing the effect of glycerin and urea on dry, eczematous skin in atopic patients. 1201 98

One hundred consecutive patients with hand eczema were patch tested with the Indian Standard Series and indigenous antigens after a detailed history and clinical examination. Both sexes were involved and the majority of them were in the age group between 20-39 years (56%). Their occupational profile varied in order of frequency from household work (37%), to masons (14%), students (11%), factory workers (7%), and others (31%). Itching was the most common presenting complaint (93%). A history of atopy was found in 36% of the patients. The predominant sites involved were the palms (43%), followed by fingers (32%), dorsum (17%), and the entire hand (8%). Dry, scaly skin was the most common morphological picture, followed by hyperpigmentation, fissuring, and lichenification. Based on history, clinical examination and patch test results, the diagnosis was made as allergic contact dermatitis in 67% of cases and irritant contact dermatitis in 15% of cases. Positive patch tests with one or more allergens were noted in 67% of the patients. Vegetables (21%) were found to be the most common sensitizers, followed by nickel sulphate (20%), potassium dichromate (18%), and others. Wet work, soaps, and detergents were found to be the most offending irritants. The present study confirmed the fact that hand eczema is a multifactorial disease caused by both irritants and allergens.
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PMID:Pattern of contact sensitivity in Indian patients with hand eczema. 1457 54

Our main aim was to determine the dermatophyte infection and colonization prevalence in canines from South Santiago, Chile. We studied 241 dogs, 121 of them presented cutaneous lesions suggestive of dermatophytosis and the other 120 were free from lesions and were considered clinically healthy. Dermatophytes were isolated from the lesions of 48.8% of animals with cutaneous diseases and from 5% of healthy dogs. Microsporum canis was the principal species isolated with a frequency of 98.3% from dermatophytosis and from all healthy carriers. The direct microscopic test showed a sensibility of 85% with a positive and negative predictive value of 74 and 79%, respectively. The highest prevalence of dermatophytosis were detected in animals up to one year old (p <= 0.05) and in dogs with high level of irritation, scaly skin, itching and alopecia (p < or = 0.05). The lesions were detected more frequently in head-neck and anterior members (p < or = 0.05). This study shows some clinical characteristics and a frequency of dermatophytes in canines that can be interesting for laboratory professionals and veterinarians.
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PMID:[Dermatophyte infection and colonization in dogs from South Santiago, Chile]. 1545 52


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