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Query: UMLS:C0033774 (pruritus)
 14,546 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The colposcope was introduced into colon and rectal surgery for the evaluation of anal and perianal disease. The standard technics of gynecologic colposcopy were used. The indications included evaluations of pruritus ani, condyloma, mass lesions, unexplained bleeding or pain, and follow-up of patients previously treated for carcinoma of the anus or lower rectum.
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PMID:Colposcopy in anorectal disease. 51 67

Four patients, 23--34 years old, who developed endometriomas at the site of an episiotomy 19 months to 11-years postpartum are reported. Pain, Swelling and pruritus varying in intensity with the menstrual cycle were present in all. Complete excision is curative. Symptoms of incompletely excised endometriomas may be controlled by local hormonal injections or systemic hormonal manipulation. The anatomy of the endometrium and its physiologic behavior are reviewed. A concept of WHY endometriomas develop is presented which is compatible with the theories of HOW they occur.
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PMID:Perineal endometrioma in episiotomy incisions: clinical features and management. 52 47

S-6436 or S-6437 was orally administered to 30 patients with bacterial infections including some patients with secondary infections. The following results were obtained: 21 patients had excellent effect, good 5, fair 2 and poor 2. The effectiveness was 86.7%. One gram (potency)/day of sustained release cephalexin was given to most of the patients divided into 2 doses after breakfast and dinner. This b.i.d. regimen was popular among outpatients as well. Staph. aureus isolated from 73.3% of the patients disappeared. Overall bacteriological effectiveness was 72.2%. In only 2 patients, side effects were observed. One had a mild pain in stomach and the other had aggravation of itching in complication of eczema. No abnormalities in laboratory studies which were conducted in some patients were found.
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PMID:[Clinical study of sustained release cephalexin (S-6436, S-6437) in dermatology (author's transl)]. 59 93

Primary cutaneous aspergillosis is rare. In this report we describe a primary skin infection by Aspergillus flavus in a child with leukemia. The lesions were characterized by erythematous macules and papules associated with pain and itching, followed by a rapid progression to ulcers and central black eschars with a raised erythematous border. A favorable response to topical nystatin therapy was observed. The multiple cutaneous lesions seen in our patient were most likely due to primary inoculation near the site of intravenous infusion with subsequent local lymphatic spread.
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PMID:Primary cutaneous aspergillosis in a leukemic child. 61 88

The term glossodynia refers to all conditions with pain and dysaesthesia of the tongue and entire oral mucosa manifesting themselves in burning, prickling, itching, stinging, and other frequently bizarre sensations as well as subjective xerostomia and bad taste. In most cases psychiatric diseases are the cause of the complex of complaints whereas local and general disorders are of only minor importance. Menopausal women with atypical depression are most often affected. Schizophrenia and abnormal personality development are far less frequent in glossodynia. After exclusion or therapy of organic disorders antidepressants are the treatment of choice in glossodynia. Thereapeutic difficulties may arise in patients suffering from marked xerostomia whose complaints may intensify during therapy because of the anticholinergic effect of most antidepressants, and in neurotic persons.
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PMID:[Psychological aspects of glossodynia (author's transl)]. 67 25

This study, designed to evaluate fenoprofen in patients with osteoarthritis, consisted of two phases: I. A double-blind crossover comparison of fenoprofen, 200 to 600 mg every six hours, to aspirin, 325 to 975 mg every six hours; II. Longterm use of fenoprofen in an open study design. During the first part of the study, both fenoprofen and aspirin were significantly better than placebo in relieving the severity and duration of pain, and in reducing stiffness. In most of the variables fenoprofen was also slightly better than aspirin. The most frequently observed side effects were abdominal discomfort, headache, pruritus, nervousness, and tinnitus. Longterm administration demonstrated the safety of fenoprofen or periods exceeding two years. Fenoprofen did not precipitate or aggravate chronic disorders, nor did it mask the symptoms of any developing disease. No interaction with concomitant drug therapy was observed.
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PMID:Fenoprofen therapy in large-joint osteoarthritis: double-blind comparison with aspirin and longterm experience. 78 Dec 34

A 41-year-old man developed intense itching without visible cutaneous changes, epigastric pressure pain, and a slight intolerance to alcohol. He was found to have persistent blood eosinophilia. The eosinophil granulocytes were of abnormal appearance in the light microscope: larger than normal, the nuclei were multilobulated (4-6 lobes), the cytoplasm contained atypical, large granules, ample glycogen, and up to 12 vacuoles. In the electron microscope too the eosinophil granules were entirely atypical, having an electron-dense matrix, often with a light central inclusion body which was inhomogeneous, having longitudinally oriented structures with a periodicity of about 10 nm. These findings are quite contrary to normal eosinophil granules. Enzymic studies of cytoplasmic enzymes from the granulocytes revealed a greatly reduced content of eosinophil cationic proteins, whereas 5 (7) other enzymes were present in a normal or slightly reduced quantity. The phagocytic capacity of the eosinophils against latex particles was normal. The patient developed generalized lymphomas, histologically very malignant, of the convoluted, acid phosphatase positive cell type (T-cell lymphoma). Sub-population studies of lymphocytes from a lymph node revealed 58% TE cells, while the remainder were B cells. At death, 3-1/2 years after the onset of symptoms, severe endomyocardial fibrosis was found. The thymus could not be identified. It is concluded that lymphomas should be described on the bais of clinical, histological, and histochemical criteria as well as studies of lymphocyte sub-populations and that the highly unusual eosinophil granulocytes still deserve particular attention. The endocardial fibrosis is assumed to have been due to substances liberated from the eosinophil cells.
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PMID:Unique eosinophil granules in a case of T-cell lymphoma. 89 57

Epidermolysis bullosa simplex was diagnosed in 4 Collie dogs. Three of the dogs were less than 6 months old when lesions were first noticed. Lesions were characterized by alopecia, erythema, edema, erythematous plaques, erosions, ulcers, crusts, atrophy, pigmentary changes, and (rarely) blisters affecting the skin over bony prominences and joints of the limbs, face, lips, and ears. Minimal to moderate pruritus or pain was manifested by chewing and licking at the affected areas of the limbs and by pawing and rubbing at the face and ears. Lesions could be induced by frictional trauma in areas of normal skin. Diagnosis was confirmed by histologic examination of affected tissues and induced lesions. Therapy with large oral doses of prednisolone and avoidance of trauma were palliative.
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PMID:Epidermolysis bullosa simplex in the Collie dog. 92 41

Pain and itch syndromes of thalamic origin were experimentally induced in rats by creation of generators of pathologically increased excitation in the gelatinose thalamic nucleus by local disturbance of the gelatinose thalamic nucleus by local distrubance of the inhibitory mechanisms in this nucleus with the aid of tetanus toxin. The latter was injected into the mentioned nucleus in the microvolumes using sterotaxis technique. The results of investigations agree with the concept of generator mechanisms of the neuropathological syndromes and the role of hyperactive determinant dispatch stations in the central nervous system activity.
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PMID:[Experimental pain and pruritic syndromes of thalamic origin]. 95 95

In three women with multiple sclerosis, paroxysmal attacks of itching occurred. There were several similarities between these attacks and other types of paroxysmal phenomena previously described in multiple sclerosis. The attacks were brief, but usually lasted several minutes, they started and ended abruptly, and recurred several times a day. The were controlled effectively by carbamazepine. It is suggested that paroxysmal itching is caused by transversely spreading ephaptic activation of axons within a partially demyelinated lesion in pain-conducting fibre tracts in the central nervous system.
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PMID:Paroxysmal itching in multiple sclerosis. 99 Jan 74


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