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Query: UMLS:C0033774 (pruritus)
 14,546 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The potential sequelae of Chlamydia trachomatis--nonspecific urethritis and post gonococcal urethritis in men and nonspecific genital infection in women--suggest a need for a chlamydial diagnostic service in clinics that treat sexually transmitted diseases. In this prospective study, over 2000 endocervical samples were obtained over an 18-month period from women presenting to a sexually transmitted diseases clinic. The isolation rate for chlamydia averaged 23.6%/month. There was no significant difference in presenting symptoms such as vaginal discharge, dysuria, pruritus, and abdominal pain between patients with chlamydial infection alone, those with gonorrhea alone, and women with no sexually transmitted disease. 178 (31%) of patients with chlamydia were sexual contacts of patients with nonspecific urethritis and 122 (22%) were contacts of men with gonorrhea. In the absence of a chlamydial service laboratory, only contacts of patients with nonspecific urethritis are likely to receive treatment, leaving 2/3 of chlamydia-positive women untreated. In 1976, an estimated 18,300 women were seen in British clinics with undiagnosed, untreated chlamydial infection. Given the magnitude and severity of this problem, a chlamydial diagnostic service should become a mandatory clinic component.
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PMID:The need for a chlamydial culture service. 48 48

An agar growth inhibition method for serotyping Ureaplasma urealyticum is described, and the results of applying this method to serotyping 338 strains of the organism are presented. The serotyped strains consisted of cloned isolates from male patients with primary and recurrent nongonococcal urethritis (NGU), isolates from symptomatic patients with other genitourinary tract infections and disorders, and isolates from asymptomatic carriers of U. urealyticum in the genitourinary tract (controls). Among 122 male patients with NGU, serotype 4 was associated most frequently (52%) with this disease at Camp Lejeune, N.C. Seventeen percent of the isolates were type 2. The remaining isolates consisted of types 1, 3, 6, and 8 and accounted for 6 to 9% each of the serotypes isolated from the NGU group. Types 5 and 7 were not isolated. Among 91 symptomatic patients with other genitourinary tract infections and disorders, U. urealyticum type 4 also was associated most frequently (37%) with these disorders. The remaining isolates, represented by types 1, 2, 3, 6, 7, and 8, accounted for 9 to 15% each of the types isolated from this group. Type 5 was not isolated. Among 125 symptomfree carriers of U. urealyticum in the genitourinary tract, type 8 was recovered most frequently (30%), whereas type 4 was isolated next most frequently (24%). The remaining isolates consisted of types 1, 2, 3, 5, and 6 and accounted for 2 to 15% each in this asymptomatic control group. Type 7 was not isolated. Of the present eight serotypes of U. urealyticum studied in this investigation, type 4 was associated most frequently with disease (NGU) and certain other disorders of the genitourinary tract at Camp Lejeune. A previously unknown association of U. urealyticum with frequently abacteriuric, unexplained pyuria (with or without urethral pruritus and dysuria) is reported, suggesting the existence of asymptomatic Ureaplasma urethritis.
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PMID:Serological typing of Ureaplasma urealyticum isolates from urethritis patients by an agar growth inhibition method. 73 Aug 28

Trichomonas vaginalis is a flagellate protozoon which in women commonly causes vaginal itching; burning, and a frothy, offensive and seropurulent yellowish discharge. Incidence of infection in women varies from 13 to 60%, and is highest during pregnancy because of excess estrogens and in women with poor hygiene or with vaginitis. In men, the incidence ranges from 9 to 37% of persons with urethral discharge. This study presents the results of the use of a single dose treatment of Trichomonas vaginitis with 2.0 gm Tinidazole. 350 women with vaginal discharge from the Gynecology Dept. of Cairo University hospitals were studied. Microscopic study of the discharge revealed T. vaginalis in 103 cases (aged 17 to 48 years). Majority of the clinical complaints (pruritus vulvae; soreness; sense of fullness in vagina and dysuria) disappeared in all cases after administration of 2.0 gm single dose of Tinidazole. Discharge; dyspareunia and soreness or pain at vulval interoitus disappeared in about 2/3 of cases; improved in about 1/4 and persisted in less than 8% (failure in these cases was attributed to other causes such as cervical erosion; bacterial infections; hormonal or other pathologic lesions in the internal genitalia). Mild gastrointestinal reaction (nausea and vomiting) were observed in 5 cases and transient urticaria in 1 case.
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PMID:Treatment of Trichomonas vaginitis with a single dose of tinidazole. 123 91

The frequency of symptoms in the case histories of 68 female patients with and of 313 without Chlamydia trachomatis infections was investigated. Dysuria, vaginal discharge and/or burning/itching in the genital region were reported by 50% (n = 34) of chlamydia-positive women and 53.7% (n = 168) of chlamydia-negative women. Clinical investigation of the chlamydia-positive patients revealed discharge in 83.8% (n = 57), contact bleeding in 38.3% (n = 26) and ectopia in 27.9% (n = 19). The corresponding investigations in chlamydia-negative women disclosed discharge in 72.8% (n = 228) women, contact bleeding in 19.8% (n = 62) and ectopia in 16.8% (n = 52). The results were significantly different as far as contact bleeding and ectopia were concerned. Only when yellow or whitish yellow discharge was distinguished from clear discharge was the difference between the two groups significant (66.7% vs 43.9%). Significant numbers of polymorphonuclear leucocytes (greater than 4 per high power field with oil immersion) were found in 52.9% of the chlamydia-positive women, as against 23% of the chlamydia-negative women. Overall, 48.7% of the women with a C. trachomatis infection were found to have notes of symptoms in the history and signs of cervicitis revealed by clinical investigation. Symptoms only were found in 1 woman, while in 36.8% of the patients signs only were found. Neither symptoms nor signs were mentioned by 13.3% of the women. These results indicate that microbiological detection of the infectious agent is obligatory for the diagnosis of C. trachomatis cervicitis.
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PMID:[The value of symptoms and clinical findings in cervical Chlamydia trachomatis infection]. 176 32

The study population consisted of 832 premenarcheal girls. Vaginal cultures are performed on 40 premenarcheal girls suffering from vulvovaginitis. All were less than 7 years old. This patients were seen in primary cares. In 23 cases (57.5%) E. coli was isolated, Enterococcus (30%), mixed flora (10%) and G. vaginalis (2.5%). Common clinical characteristics were pruritus (97.5%), vaginal discharge (67.5%). Dysuria and abdominal pain constituted accompanying symptoms. Only in one case masturbation was observed.
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PMID:[Vulvovaginitis in premenarche girls. A preliminary study]. 178 45

The history and the results of clinical investigations in 74 patients with and 262 men without urethral Chlamydia (C.) trachomatis infection were evaluated: symptoms such as dysuria, discharge and/or burning/itching in the genital region were reported by 77% (n = 57) of the patients with an infection and 63.4% (n = 166) of the men without an infection. Upon clinical investigation, discharge was found in 55.4% (n = 41) of the chlamydia-positive patients and in 47.7% (n = 125) of the chlamydia-negative men. Only when yellow, whitish yellow and clear discharge were distinguished from one another was the difference between the two groups of patients (56.1% versus 12%) significant. Microscopic signs of urethritis, i.e. significant numbers of polymorphonuclear leukocytes (greater than 4 per high-power field and oil immersion) were detectable in the smears of 59.5% (n = 44) of the chlamydia-positive patients, in contrast to 15.6% (n = 41) in the smears of chlamydia-negative men. Overall, 67.6% (n = 50) of the patients with a C. trachomatis infection reported symptoms in the anamnesis combined with signs of urethritis upon clinical and microscopic investigation. There were 9.5% (n = 7) of the patients who either mentioned symptoms or showed clinical signs, and 13.5% (n = 10) who neither mentioned symptoms nor showed clinical signs. These results indicate that microbiological detection of the infectious agent is obligatory for diagnosis of urethral infection with C. trachomatis.
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PMID:[The value of symptoms and findings in urethral Chlamydia trachomatis infection]. 193 97

Cytolytic vaginosis, a not uncommon condition, is frequently misdiagnosed because it is confused with Candida. Many practitioners rely on their clinical judgment alone rather than the use of high-quality microscopes and the results of a wet smear. Compounding the problem of misdiagnosis is that patients assume that their symptoms are caused by a yeast infection, which results in telephone requests for medication from their physicians instead of an office consultation. Cytolytic vaginosis is characterized by pruritus, dyspareunia, vulvar dysuria, and cyclical increase in symptoms more pronounced during the luteal phase. Diagnostic criteria include a high risk of suspicion; the absence of Trichomonas, Gardnerella, or Candida on wet smear; an increased number of lactobacilli; a paucity of white blood cells; evidence of cytolysis; and the presence of discharge; and a pH between 3.5 and 4.5. Treatment entails use of sodium bicarbonate douches.
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PMID:Cytolytic vaginosis. 195 82

Forty cancer patients were randomly assigned to two groups (n = 20). All had incapacitating pain unresponsive to the usual non opioid analgesic drugs. An epidural catheter was set up at the level of the most painful metamere, and made to pass subcutaneously so as to exit either in the supraclacicular fossa, or on the patient's flank. At T0, the patients were given 4 mg morphine hydrochloride diluted in 10 ml normal saline. Thirty min later, patients in the naloxone group (group N) were given a 0.4 mg bolus, followed by a constant rate infusion of 5 micrograms.kg-1.h-1, of naloxone hydrochloride during 18 h. Patients in group P (placebo) were given normal saline instead. The degree of pain was studied with a visual analogue scale and analgesia was assessed by a clinician on a five point scale. These two parameters were obtained half an hour after the injection of morphine and 2, 4, 6 and 24 hours later. At the same time, the patients were questioned about adverse side-effects: nausea, vomiting, pruritus, dysuria, urinary retention. Respiratory depression was assessed clinically and biologically (blood gas measurements at the afore mentioned times). Heart rate, systolic and diastolic blood pressure were also measured. There was no statistically significant difference between the groups in quality and duration of analgesia. Pain reached its lowest level 4 h after the injection of morphine, returning to half its original value at the 24th h. This was also true for the incidence of nausea (11 in group N, 5 in group P), vomiting (3 in both groups), and urinary retention (6 in group P, 5 in group N).(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Prevention by naloxone of adverse effects of epidural morphine analgesia for cancer pain]. 205 46

Data concerning 604 girls up 18 year old were analysed. On the basis clinical symptoms and results of culture of various biological materials on selected media--the monofocal Trichomonas infection concerning the most often vulva and vagina, rarely urethra or other regions of urinary organ as well as the multifocal Trichomonas infection, particularly complicated by mycosis were proved. It was found the convergence statistically significant (P less than or equal to 0.5) of the invasion of T. vaginalis with some symptoms of inflammation of genital and urinary organs; the highest values of Pearson-Bravais coefficient was obtained in Trichomonas infection of genital organs and vaginal discharges, pain of vulva and vagina, the picture of colpitis maculosa, but in the multifocal one also with itching and pain in urethra and dysuria. T. vaginalis without symptoms occurred very seldom in the girls.
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PMID:[Analysis of the relations between selected symptoms of inflammation of the genital and urinary organs and invasion of Trichomonas vaginalis]. 213 96

Vaginitis is one of the most frequent infections of the female genital system and, in the United States, represents the main reason for gynecological consultation. Candida albicans, Trichomonas vaginalis and Gardnerella vaginalis are responsible for 90% of cases of vaginal phlogosis. It has been calculated that a percentage varying between 5% and 40% of the female population will suffer, at least once in their lifetime, from an episode of vaginal candidosis. The re-appearance of symptoms after suspension of the antimycotic therapy still represents an unsolved and obscure problem from the etiopathogenetic point of view. The incidence of recurrences in women suffering from various forms of vaginal candidosis, according to the Authors, is between 5% and 25%. Considering the uncertainties existing regarding the clinical and etiopathogenetic definition of recurrent vaginitis we carried out a perspective study, at the General Out-patient Department of the II Obstetrical and Gynecological Clinic of "La Sapienza" Rome University in collaboration with the Bacteriological Laboratory of the III Medical Clinic of "La Sapienza" Rome University, on a group of 60 women suffering from recurrent vaginitis. We included in the study in the period 1 October 1987 - 30 September 1988 60 women reporting to the General Out-Patient Department of the II Obstetrical and Gynecological Clinic of the "La Sapienza" Rome University. These patients complained about the appearance of a leukorrhea or a leukoxanthorrhea in combination with at least one of the following symptoms: burning sensation; itch; dyspareunia; dysuria; recurring cystitis. All the women reported in their case histories having suffered from at least three episodes of recurrent vaginal candidosis in the previous twelve months. Diagnosis had been established on the basis of fresh microscopic examination with determination of the vaginal pH on the occasion of the first episode only; whereas clinical examination only was undertaken on the occasion of the subsequent ones. In 30% of patients (or 18 cases) the diagnosis of the subsequent episodes was "telephonic". In all cases, at each episode, a local therapy with antimycotic drugs had been prescribed. Following the introduction of a sterile speculum sterile swabs were used to remove 2 samples of the fluid present at the level of the posterior vaginal fornix. The first swab was placed in a test-tube containing 2 ml of prereduced transport broth (brain-heart infusion broth oxoid) for the successive aerobe and anaerobe cultures.(ABSTRACT TRUNCATED AT 400 WORDS)
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PMID:[Recurrent vaginitis]. 248 80


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