Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0033774 (pruritus)
 14,546 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Although cutaneous larva migrans is more commonly seen in the southeastern US and tropical regions of the world, patients with such parasitic involvement may present in other non-endemic areas for various reasons, particularly travelers returning from tropical vacations. Awareness of the clinical presentation and symptomatology of cutaneous larva migrans is important for all physicians, including those practicing in northern climates, for prompt recognition and effective treatment of the disease. Furthermore, cutaneous larva migrans should be of particular interest to podiatrists, because the infestation commonly involves the feet, and a patient may initially present for treatment of secondary manifestations, ie, dermatitis, pruritus, or infection, as in this case report.
 ...
PMID:Management of complex pedal cutaneous larva migrans. 233 29

A 53-year old patient was admitted because of severe urticaria and itching aggravating since 9 months. Laboratory findings like increased sedimentation rate and leucocytosis were suspicious for an infection-associated allergy or a paraneoplastic syndrome. After exclusion of a gastro-intestinal tumor search for the source of a possible infection was intensified by several fecal analyses and trophozoites were found indicating an infestation of the small bowel by Giardia lamblia. Finally lamblia were detected in duodenal aspirate. After therapy with metronidazole 3 x 400 mg/die for 10 days all parameters of infection were normalized and the patient was permanently relieved from symptoms.
 ...
PMID:[Urticaria, pruritus]. 272 16

The incidence of mange in dairy buffalo in India has increased significantly in recent years. The authors record an outbreak of mange affecting a dairy herd stocking about 30,000 buffalo and 1000 cows. The mange mites were either Sarcoptes scabiei or Psoroptes ovis, or a mixed infestation of both. The morbidity rate was 5-30% varying from group to group, with 100% in a severely affected group. Signs noticed were progressive dermatitis, alopecia, keratinization, skin thickened and wrinkled, intense itching and marked loss of condition often ending in death. Great losses of young animals from mange and gastrointestinal nematodes are very common in dairy herds in India. In view of their economic importance, the activity of ivermectin against naturally occurring mange and parasitic infections of adult buffalo and buffalo calves was determined. Ivermectin was administered by subcutaneous injection (IVOMEC 1% w/v - MSD AGVET) at a dose of 200 mcg kg-1 body weight. The efficacy was ascertained from the disappearance of mites from skin scrapings and the reduction in numbers of worm eggs in the faeces. The results of the treatment were dramatic: the mites disappeared within 2 weeks of the drug being administered in the majority of animals, with marked improvement in skin lesions. Four buffalo which had their entire body surface affected with mange needed a second dose on Day 28 for complete recovery. The effect on the nematodes was equally spectacular, with infections of Neoascaris vitulorum, Trichostrongylidae, Oesophagostomum spp. and Bunostomum being eliminated within 1 week of treatment.
 ...
PMID:Efficacy of ivermectin against mange and gastrointestinal nematodes of buffalo (Bubalus bubalis). 274 1

A total of 1,167 stool specimens collected from 0.6-6 years old patients attending King Abdel Aziz University Hospital (KAUH) in Riyadh, were examined for intestinal parasites. Of these 243 (20.8%) were positive. Giardia lamblia (13.5) and Enterobius vermicularis (4.2%), were the commonest parasites found. Other parasites present include Ascaris lumbricoides, Entamoeba histolytica and Hymenolepis nana. Abdominal pain (38.6%) and diarrhoea (27.6%) were the most common causes of referral presented among both males and females examined groups. Out of 211 patients positive for different parasites and showing different causes of referral, 45.5% were accompanied with abdominal pain and 22.3% having pruritus ani, while the percentage of patients having diarrhoea and positive for different parasites (9.5%) are less. It has been concluded that diarrhoea is not a major sign of parasitic infestation in 0.6-6 years old age group. Other causes of referral include, loss of appetite, underweight and failure to thrive which are mainly associated with Giardia lamblia infection.
 ...
PMID:Pattern of intestinal parasitic infection in preschool children in Riyadh, Saudi Arabia. 280 81

The pinworm is one of the most common intestinal parasites in humans. The adult worms reside and mate in the area of the cecum and ascending colon. The females migrate to lay their ova in the perianal area. Perianal itching is the cardinal symptom of pinworm infestation. Collection of pinworms or ova from the perianal area permits diagnosis. Meticulous personal hygiene is essential to prevent spread of the parasites.
 ...
PMID:Pinworms. 304 68

A case of crusted (Norwegian) scabies is reported in a child who was a recipient of a bone marrow transplant. The infestation is presumed to have predated the bone marrow transplant and continued asymptomatically during chemotherapy and total body x-irradiation in preparation for transplant. The child was asymptomatic until 23 days after transplantation, when bone marrow engraftment was attained. The altered host-parasite relationship is emphasized by the observation that the onset of symptomatic pruritus coincided with successful engraftment.
 ...
PMID:Crusted (Norwegian) scabies. Occurrence in a child undergoing a bone marrow transplant. 354 94

Chigger infestations are caused by mite larvae that feed on the host's epidermal cells. The combination of digestive enzymes secreted by the mite and the immune response of the host produces the typical "chigger bite." Intense pruritus is the usual response, but more severe reactions and chigger-borne disease may also occur. Treatment is primarily symptomatic and consists of antipruritics, antihistamines and steroids. Chigger infestation may be minimized by the use of proper clothing and insect repellents.
 ...
PMID:Chiggers. 361 52

Eleven patients with delusions of infestation were treated with pimozide using a double-blind crossover technique. Ten out of 11 patients improved. The investigation showed significant relief of itch and delusions during pimozide treatment. Brief Psychiatric Rating Scale (BPRS) points decreased significantly. Adverse effects were few by 2 patients showed dose-related depressive reactions during treatment. Pimozide treatment of patients with delusions of infestation should be entrusted to dermatologists, because these patients with delusions differ from most patients attending psychiatric clinics in that they have a monosymptomatic hypochondriacal psychosis.
 ...
PMID:Delusions of infestation treated by pimozide: a double-blind crossover clinical study. 617 38

Enterobiasis or pinworm infestation is an ubiquitous infection often seen in primary care settings. Incidence and prevalence are difficult to identify as it is believed that many cases go undiagnosed. Diagnosis, most commonly made in the school-aged child after complaints of nocturnal pruritus ani, can be made either by a cellulose tape test or by parental or self-report. A number of effective antihelminthics are available for treatment. It is thought that all close family members should be treated when a confirmed case exists and that retreatment should be given after a two-week interval to ensure eradication of the parasite. The nurse practitioner can be instrumental in providing treatment, education, support and reassurance to families with pinworms.
 ...
PMID:Enterobiasis. 663 80

In 1981, outbreaks of itchy skin rashes were reported accompanying the heavy infestation of gypsy moths (GM) in the Northeastern United States. The rash problem was widespread and a considerable public annoyance. In the spring of 1982, during the period of greatest contact with the caterpillars, a telephone survey was carried out in a highly infested community (HI) and a minimally infested community (LO). Information was collected from 1,000 persons, representing more than 90 per cent of those selected for study. The one-week risk of rash was 10.4 per cent in the HI area and 1.6 per cent in the LO area, for a risk ratio (RR) of 6.5. The occurrence of rash was strongly related to a history of having had a rash in the previous year or having had a caterpillar crawl on the affected area. The combination of both factors additively increased the risk of rash. Hay fever and hanging the wash outside were other related variables. History of allergies other than hay fever since childhood and the use of insecticides were unrelated to rash occurrence.
 ...
PMID:An epidemiologic study of gypsy moth rash. 674 70


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>