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Query: UMLS:C0033774 (pruritus)
 14,546 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The intensive morbidity index in respect of allergic dermatoses has made up 12.07 in 1986, allergic dermatitis being the most prevalent (72%). The morbidity has been the highest among subjects aged 21 to 40. Seasonal changes in the allergic dermatoses incidence rates have been determined: skin itching, urticaria, and neurodermatitis have been the most prevalent in October, whereas eczema occurred mostly in May.
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PMID:[Morbidity from allergic dermatoses and pruritus in Blagoveshchensk]. 276 8

The contribution of secondary infection to severity and tendency to relapse in atopic dermatitis during childhood has been assessed. A total of 57 children aged between 4 months and 14 years were followed for an average of 4.73 months. A secondary infection was diagnosed in 22 (31.4%) of 70 relapses, since the lesions only subsided with antibiotics active on the bacteria isolated from the skin, usually a coagulase-positive Staphylococcus aureus. The eczema was more severe at presentation and hypogammaglobulinemia G more often found in those children who were more susceptible to secondary infections. The hypogammaglobulinemia G was present in 13 out of the 57 patients, but it normalized with age and was not correlated with IgE levels. In the children in whom the relapse or the worsening of the eczema could be attributed to secondary infection because of the positive response to the antibiotic treatment, the lesions had the appearance of pustules or showed more exudation, although in some cases only the worsening of the erythema and itching was observed. A secondary bacterial infection should be considered a likely cause of relapse or worsening of atopic dermatitis. Furthermore it may be that, at least in first year of life, hypogammaglobulinemia G is part of an immunologic impairment of atopic dermatitis which favors the susceptibility to secondary infections.
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PMID:The effect of bacterial infection in the worsening of atopic dermatitis: correlations with humoral immunologic patterns. 276 15

The simultaneous presence of psoriasis and atopic dermatitis was checked for in 1065 patients with psoriasis and was found in 18 of them (1.7%), which is in keeping with the statistical probability. In these 18 the efflorescence was also examined histologically. All 18 (100%) reported marked pruritus; white dermatographism was observed in 16 patients (89%); in 15 patients (83%) psoriatic phenomenas could be produced, and 11 patients (61%) also had allergic rhinitis or bronchial asthma. Immunologically, 16 of the 18 patients (89%) showed elevated IgE levels, the geometric mean level being 888 IU/ml. The HLA-Cw6 was positive in 9 patients (50%).
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PMID:[Concomitant psoriasis vulgaris and atopic dermatitis. A study of 1,065 patients with psoriasis]. 279 60

A simple system for baseline grading the severity of atopic dermatitis in clinical work, is presented. The grading, which may be carried out on the basis of one single consultation, permits distinction between mild, moderate and severe atopic dermatitis by means of a score summation using the following parameters: 1) extent (by "rule of nine"), 2) course (via history) and 3) intensity (disturbance of night's sleep by itching).
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PMID:Grading of the severity of atopic dermatitis. 280 Aug 95

The effects of a dietary supplement of n-3 fatty acids in patients with atopic dermatitis were investigated in a 12-week, double-blind study. The experimental group received 10 g of fish oil daily, of which about 1.8 g was eicosapentaenoic acid. This amount of eicosapentaenoic acid can be obtained from a daily intake of fat fish. The controls received an iso-energetic placebo supplement containing olive oil. Compliance was monitored by gas-chromatographic analysis of the fatty acid pattern in serum phospholipids. Results favoured the experimental group with regard to scale (P less than 0.05), itch (P less than 0.05) and overall subjective severity (P less than 0.02) as compared to the controls.
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PMID:Effect of dietary supplementation with eicosapentaenoic acid in the treatment of atopic dermatitis. 282 59

Low-frequency (2 Hz) transcutaneous electrical nerve stimulation (TNS) may produce prolonged and widespread sympatho-inhibition resulting in improved skin microcirculation with increased skin temperature in patients with peripheral vascular insufficiency. The method has previously been used successfully to improve peripheral circulation in such patients and to accelerate healing of chronic skin ulcers of various etiology. The present report deals with healing of atopic eczema and relief of pruritus by low-frequency TNS treatment in a patient who was followed for 2 years, the first 8 months with daily recordings of the effects, and then for an additional 16 months during which period TNS only occasionally was used. TNS also produced increased plasma levels of ACTH, cortisol and vasoactive intestinal polypeptides (VIP). The mechanisms of the favourable clinical effects are discussed.
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PMID:Successful treatment of itching and atopic eczema by transcutaneous nerve stimulation. 289 Feb 72

The use of the nonsedating antihistamine terfenadine (60 mg twice daily) in the treatment of chronic idiopathic urticaria and contact urticaria associated with atopic dermatitis was assessed. In patients with chronic idiopathic urticaria, terfenadine was found to be as effective as the traditional antihistamine clemastine in reducing the number of wheals and the severity of itch, without causing drowsiness. A separate study showed terfenadine to be of value in some patients with atopic dermatitis and a history of contact urticaria.
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PMID:Terfenadine in the treatment of chronic idiopathic urticaria and atopic dermatitis. 290 17

A 38-year old patient had been suffering, since the age of 17, from membranoproliferative glomerulonephritis associated with chronic atopic eczema and recurrent sinusitis. Bouts of eczema with severe itching occurred simultaneously with sinusitis and proteinuria. Permanently extreme serum IgE levels (greater than 10,000 IU/ml), defective neutrophil chemotaxis and monocyte phagocytic function (Buckley's syndrome) were present. Because cyclosporin reduces excessive IgE levels in Brown Norway rats with mercuric chloride nephritis, we gave the patient this drug in daily doses of 3-4 mg/kg. A dramatic improvement resulted within a few days: itching disappeared, the eczema progressively cleared, proteinuria decreased to less than 0.5 g/day and serum IgE levels to 4000 KIU/l. Reduction of dosage was followed by recurrence of all clinical and biological signs. In spite of the improvement obtained, serum creatinine levels, which were initially high (200-250 mumol/l) rose up to 300 mumol/l after one year of treatment.
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PMID:[Membranoproliferative glomerulonephritis associated with Buckley's syndrome treated with cyclosporin]. 295 74

Infantile seborrhoeic dermatitis is a dermatosis affecting infants characterized by little or no itching and by completely typical skin symptoms, distribution and evolution. Infantile seborrhoeic dermatitis should therefore be differentiated from atopic dermatitis and from diaper-rash although interferences be possible. In fact the high frequency of the atopic dermatitis and of diaper rash may cause these two manifestations to sometimes superimpose on infantile seborrhoeic dermatitis. This in turn causes rather complex clinical situations that may be very hard, but not impossible to diagnose if use is made of laboratory findings to support clinical features. The pathogenesis and etiology of infantile seborrhoeic dermatitis are still debated although recent results assign the dominant role to Candida albicans. This mycete also plays a relevant role in the genesis of diaper rash and particularly of Leiner's exfoliative erythrodermas, which can be interpreted as a generalized and erythrodermic expression of infantile seborrhoeic dermatitis. Systematic cultural investigations and appropriate antimycotic treatments, that would stimulate antibody response, will allow to clarify in the near future this interesting etiological problem, with important therapeutical consequences.
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PMID:[Infantile seborrheic dermatitis and related syndromes. Diagnostic and pathogenetic problems]. 295 82

201 patients with skin problems caused in their own opinion by working with visual display terminals (VDTs) were referred and examined. 18% claimed that their condition improved overnight and 21% that it did so over the weekend. In 25 patients, the skin problems occurred mainly on the cheek turned towards the VDT. Half the patients had rosacea, but their subjective skin symptoms were generally more severe than those in ordinary cases of rosacea, i.e., severe pain, itching and burning. The rest of the patients mainly had common facial dermatoses such as seborrhoeic eczema, acne vulgaris and atopic dermatitis. The patients' skin types, judged by their response to ultraviolet light, did not differ from those of a control population. 18% had non-specific skin problems, e.g., itching and redness. This latter group of patients most closely resembles those cases previously described amongst VDT-workers. An attempt to correlate skin problems with VDTs' electrostatic field strength was unsuccessful because of difficulties in eliminating it. Of 52 electrostatic shields placed in front of patients' VDTs, 38 were defective and 9 were wrongly earthed. The prevalence of migraine-like headache was 40%, which is much higher than in a control population. There was no great use of cosmetics by the study population. When followed up after an average of 8 months, 2/3 of the patients had fewer skin complaints. The question of whether the prevalence of skin problems in general is higher amongst individuals using VDTs than in a control population is addressed in a current study.
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PMID:Skin problems in workers using visual display terminals. A study of 201 patients. 297 51


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