Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0033687 (proteinuria)
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Human Gene/Protein
STOX2 10.4
ZNF554 10.4
SYNAPTOPODIN 10.4
CLCN5 9.6
EMI5 9.4
HLA-DR beta1 9.4
KBP-1 9.4
ZHX3 protein 9.4
chloride channel CLC-5 9.4
intrinsic factor-vitamin B12 receptor 9.4
NEPH1 9.2
type IV collagen alpha3 chain 9.1
podocin 8.9
Nephrin 8.9
Crumbs homolog 2 8.8
kin of IRRE like 8.8
enabled homolog 8.8
INO80B 8.8
ACTL7B 8.8
TBC1D8B 8.8
DC30 8.8
PODXL protein 8.8
growth arrest and DNA-damage-inducible 45 alpha 8.8
FSGS 8.8
ClC-5 8.8
tensin2 8.7
THSD7A 8.6
nephrin 8.6
Podocin 8.6
phospholipase A2 receptor 8.6
PLA2R 8.6
NEPH2 8.6
diacylglycerol kinase epsilon 8.6
CLC-5 8.5
CUBN 8.5
synaptopodin 8.5
TGFR-3 8.4
kinesin family member 3B 8.4
MYH9 protein 8.4
neural epidermal growth factor-like 1 8.4
SNRPB2 8.4
calcineurin binding protein 1 8.4
LMNA protein 8.4
ARL4D 8.4
PTPROt 8.4
cubilin 8.2
COL4A3 8.2
COL4A4 8.2
ADCK4 8.1
MGN 8.1
acid sphingomyelinase-like phosphodiesterase 8.1
FCRN 8.1
tensin 2 8.1
GLEPP1 8.1
endothelial nitric oxidase synthase 8.1
JPD 8.1
myosin, heavy chain 9, non-muscle 8.1
Cubilin 7.9
Alport syndrome 7.9
LAMB2 7.9
podocalyxin 7.8
KANK4 7.8
carnosinase 1 7.8
mindbomb homolog 1 7.8
STOX1 7.8
APOL2 7.8
APELIN 7.8
INPP5B 7.8
ACTL7A 7.8
KCMF1 7.8
ZHX3 7.8
COL4A5 7.7
ZHX1 7.7
OCRL1 7.7
forkhead box O4 7.6
CFHR5 7.6
CKR-1 7.6
OFD1 protein 7.6
NPTN 7.6
megalin 7.5
more...
Disease
Hypercalciuric rickets 10.4
Nodular diabetic glomerulosclerosis 10.4
Diffuse glomerulosclerosis 10.4
xerotic keratitis 10.4
Renal tubulitis 10.4
Chronic focal glomerulonephritis 10.4
Hypercalcemic nephropathy 10.4
Homozygous alpha thalassaemia 10.4
True proteinuria 10.4
Acute subendocardial infarction 10.4
Febrile proteinuria 10.4
Hypertensive renal failure 10.4
Residual proteinuria 10.4
hormone related cancer 10.4
Steroid-dependent nephrotic syndrome 10.4
proteinuria 10.4
Tuberculous pyelonephritis 10.4
Proteinuria 10.4
Nephrotic range proteinuria 10.2
facio-oculo-acoustico-renal syndrome 10.1
Acute proliferative glomerulonephritis 10.0
Endocapillary GN 10.0
Nerve deafness 9.8
Nephritic syndrome 9.8
Familial nephropathy 9.8
Frasier Syndrome 9.8
Clinical diabetic nephropathy 9.8
orthostatic proteinuria 9.8
Renal proteinuria 9.8
Recurrent proteinuria 9.8
Segmental glomerulosclerosis 9.6
C1q nephropathy 9.6
Transient proteinuria 9.6
Henoch-Schoenlein nephritis 9.6
Glomerulonephropathy 9.6
proteinuria in pregnancy 9.5
Dent's disease 9.5
Heymann nephritis 9.4
Renal azotemia 9.4
ACE inhibitor fetopathy 9.4
Familial hypomagnesaemia-hypercalciuria 9.4
kidney; damage 9.4
malignant lymphoma, colon 9.4
endotheliosis 9.4
Imerslund 9.4
Mixed proteinuria 9.4
IgM nephropathy 9.2
Mesangial proliferative glomerulonephritis 9.2
Congenital nephrotic syndrome 9.1
Fibrillary glomerulonephritis 9.1
Minimal change disease 9.0
Focal segmental glomerulosclerosis 9.0
Microproteinuria 9.0
Post-infectious glomerulonephritis 9.0
Acute renal impairment 9.0
Minimal change nephrotic syndrome 8.9
membranous nephropathy 8.9
Renal amyloidosis 8.9
glomerulosclerosis 8.8
Familial haematuria 8.8
GFND 8.8
Postpartum eclampsia 8.8
Acute on chronic renal failure 8.8
IgD MGUS 8.8
Monoclonal paraproteinemia 8.8
Acute nephropathy 8.8
Serum potassium increased 8.8
Incipient diabetic nephropathy 8.8
stage III pancreatic cancer 8.8
Renal thrombosis 8.8
Light chain myeloma 8.8
Hereditary nephritis 8.8
dipetalonemiasis 8.8
nephrotic syndrome 8.7
glomerulopathy 8.7
Masugi nephritis 8.7
NPHS2 8.6
Mesangioproliferative glomerulonephritis 8.6
Renal tubular dysfunction 8.6
Cryoglobulinemic glomerulonephritis 8.6
more...
Symptom
Dipstick hematuria 10.4
General symptoms and signs 9.4
Cloudy urine 8.4
Painless hematuria 8.4
SLE-like symptoms 8.2
Retro-orbital pain 8.1
Joint tenderness 8.1
Upper back pain 7.8
lipuria 7.6
CVA tenderness 7.6
hypoproteinemia 7.2
sense loss 7.1
chyluria 7.0
pedal edema 7.0
leg edema 6.7
Intermittent fever 6.7
oliguria 6.6
SYMPTOMS 6.5
KIDNEY 6.4
excessive urination 6.4
polyuria 6.2
loss of feeling 6.2
Limb weakness 6.2
Action myoclonus 6.2
Upper abdominal pain 6.1
High weight 6.1
Scrotal pain 5.8
loss of taste 5.7
loin pain 5.6
Flu-like symptoms 5.6
Multiple symptoms 5.6
vaginal itching 5.3
flank pain 5.3
polydipsia 5.3
ketonuria 5.2
lumbar back pain 4.9
carpopedal spasm 4.8
livedo 4.7
periorbital edema 4.7
arthralgia 4.6
phosphatemia 4.6
dark urine 4.6
GI irritation 4.4
renal pain 4.3
hepatomegaly 4.3
staggering gait 4.2
Cushingoid 4.2
Cushingoid 4.1
right upper quadrant pain 4.1
hepatosplenomegaly 4.1
orthopnea 4.1
dysuria 4.1
Pain at rest 4.0
decreased appetite 3.9
hyperemesis gravidarum 3.9
growing pains 3.8
renal colic 3.7
asthenia 3.7
abdominal fullness 3.7
Physical findings 3.6
disturbed balance 3.5
polymyalgia 3.5
splenomegaly 3.4
prostration 3.4
facial droop 3.4
myalgia 3.4
left upper quadrant pain 3.3
anorexia 3.3
night sweats 3.3
abdominal pain 3.3
intestinal bleeding 3.3
lethargy 3.3
hemoptysis 3.3
blurred vision 3.3
Signs and Symptoms 3.3
urinary frequency 3.2
lassitude 3.2
bone pain 3.2
generalized rash 3.2
nocturnal polyuria 3.2
more...
Drug
Azaconazole 10.4
Spanidin 10.4
Edratide 9.4
Carbetimer 9.1
Dilazep dihydrochloride 8.8
Furazabol 8.4
Solganal 8.2
Aranidipine 7.8
Camostat mesilate 7.6
Acthar 7.5
Candoxatril 7.4
Ifetroban 7.2
Dexamethasone palmitate 7.1
Aliskiren 7.0
Ramipril 7.0
Bindarit 6.8
Trandate 6.7
Omacor 6.5
Candoxatril 6.5
Roquinimex 6.5
Fenoprofen calcium 6.4
Zomepirac sodium 6.4
Agalsidase alfa 6.4
Mizoribine 6.4
Benazepril hydrochloride 6.3
Lotrel 6.3
Naropin 6.3
Trandolapril 6.3
Redux 6.3
Belimumab 6.1
Sodium sulfate 6.1
Bucillamine 6.1
Bevacizumab 6.1
Plaquenil 6.0
Plaquenil 5.9
Cilnidipine 5.9
Rapamune 5.9
Tiopronin 5.9
Opana 5.8
Oxyphenbutazone 5.8
Olmesartan 5.8
Eculizumab 5.8
Aliskiren fumarate 5.8
Nephron 5.8
Valsartan 5.7
Aldomet 5.7
Arachidonic Acid 5.7
Trandate 5.7
Oxyphenbutazone 5.7
Prednisone 5.7
Cardura 5.7
Cardura 5.7
Enalapril maleate 5.6
Tora 5.6
Tenidap 5.6
Captopril 5.6
Cicletanine 5.6
Azelnidipine 5.6
Fenoprofen 5.4
Serum albumin 5.4
Fabrazyme 5.4
Methyldopa 5.4
Ridogrel 5.4
Cellcept 5.4
Cellcept 5.4
Magnesium sulfate 5.4
Methylprednisolone 5.3
Perindopril 5.3
Axitinib 5.3
Minipress 5.3
Rosuvastatin 5.3
Rituximab 5.2
Lescol 5.2
Nephron 5.2
Tenofovir 5.2
Antithrombin III 5.1
Vitamin-E 5.1
Abatacept 5.1
Pirfenidone 5.1
Dazmegrel 5.1
more...
Enzyme
ceramide trihexosidase 7.2
N-acetylglucosamine 2-epimerase 6.1
alpha-galactosidase 5.9
prostasin 5.7
ACE 5.6
LTC4 synthase 5.4
proteinase-3 5.4
renin 5.4
Thy1 5.3
DAP II 5.2
alanine aminopeptidase 5.1
lecithin:cholesterol acyltransferase 5.1
aspartyl aminopeptidase 5.1
N-acetylmannosamine kinase 5.0
aminopeptidase A 4.8
HK2 4.7
cysteine conjugate beta-lyase 4.7
site-1 protease 4.6
phosphoinositide 5-phosphatase 4.5
GP-I 4.5
carnosinase 4.4
GD3 synthase 4.4
C3 convertase 4.2
dimethylarginine dimethylaminohydrolase 4.1
inosine triphosphatase 4.1
galactosylhydroxylysyl glucosyltransferase 4.0
C3 convertase 4.0
C3b inactivator 3.9
tyrosine phenol-lyase 3.9
ketohexokinase 3.7
site-1 protease 3.6
pantetheinase 3.6
ancrod 3.6
angiotensin-converting enzyme 2 3.5
cathepsin L 3.5
calcineurin 3.4
leucine aminopeptidase 3.4
PRA 3.4
NADPH oxidase 3.4
AGT 3.4
cholesterol acyltransferase 3.4
IMP dehydrogenase 3.4
tRNase Z 3.3
NADPH oxidase 3.3
MTD 3.1
CD13 3.1
arachidonate 5-lipoxygenase 3.1
dipeptidyl peptidase IV 3.1
kallikrein 3.1
CFI 3.1
gamma-glutamyl transpeptidase 3.1
endothelin-converting enzyme 3.1
aldose reductase 3.0
neutral sphingomyelinase 3.0
chymase 3.0
AST 2.9
plasmin 2.9
ADPase 2.9
3-hydroxy-3-methylglutaryl coenzyme A reductase 2.9
alpha-L-fucosidase 2.8
nucleotide pyrophosphatase 2.8
thromboxane synthase 2.8
urokinase-type plasminogen activator 2.8
homogentisate 1,2-dioxygenase 2.8
cathepsin C 2.8
lactase-phlorizin hydrolase 2.7
aminopeptidase P 2.6
arylamine N-acetyltransferase 2.6
soluble epoxide hydrolase 2.6
3-hydroxy-3-methylglutaryl-CoA reductase 2.6
CPM 2.6
PRT 2.6
type III procollagen 2.5
AMP-activated kinase 2.5
PAH 2.5
GCA 2.5
oxytocinase 2.5
transpeptidase 2.4
isoamylase 2.4
heme oxygenase 2.4
more...
Compound
C6H10O7 10.4
C6H10O7 10.4
Actol 10.4
C6H10O7 10.4
4-amino-2-chlorophenol 9.4
Spiroplatin 9.4
alpha-D-Galacturonic acid 9.4
C6H10O7 9.4
Phensuximide 9.2
Dimethylaminopropionitrile 8.8
hex-2-ulosonic acid 8.8
C16H16N2O2 8.8
E 39 8.8
Dilazep dihydrochloride 8.8
L-Guluronic acid 8.8
NDPS 8.7
2-Keto-D-gluconic acid 8.4
2,5-DCA 8.4
D-Mannuronic acid 8.4
Benziodarone 8.4
Urobilinogen 7.8
4-amino-2,6-dichlorophenol 7.6
Urobilinogen 7.6
DCPM 7.4
S 35 7.4
Cystine 7.3
Merbarone 7.3
SAN 7.2
Benazepril 7.1
Paricalcitol 7.1
MG 1 7.1
2-Keto-L-gulonic acid 7.1
L-Iduronic acid 7.1
C4H6N2O2 7.1
Sulfosalicylic acid 6.9
Glycodeoxycholate 6.8
ANCA 6.8
2-amino-4-chlorophenol 6.7
2-amino-4-chlorophenol 6.7
creatinine 6.7
Biuret 6.6
Enalapril 6.6
Mycophenolate mofetil 6.5
Forsythiaside 6.4
Pristane 6.4
Irbesartan 6.4
Fastin 6.3
LPR 6.2
Complement factor B 6.2
Ricinine 6.2
Zopolrestat 6.1
Inox 6.1
Cytembena 6.1
Direct Red 2 6.1
PIH 6.0
Sodium sulfate 5.9
Quinapril 5.9
Candesartan 5.8
Moexipril 5.7
Telmisartan 5.7
Losartan 5.7
Gb3 5.7
8-Bromo-cyclic AMP 5.7
Candesartan cilexetil 5.6
4-aminobenzamide 5.6
Homocarnosine 5.4
Methylprednisolone 5.4
Perindopril 5.3
Minipress 5.3
S 9 5.3
Salvianolic acid A 5.3
PAN 5.3
Magnesium sulfate 5.3
Eplerenone 5.3
Fosinopril 5.2
Magnesium sulfate 5.1
Cerivastatin 5.1
Tributyltin chloride 5.1
Aerobactin 5.1
Dihydralazine 5.1
more...