Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0033687 (
proteinuria
)
24,015
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Treatment of female NZB/W F1 mice with
Nafoxidine
, an anti-estrogen, led to delayed manifestation of autoimmune features. Such treated mice had reduced anti-DNA antibodies, reduced
proteinuria
, and improved survival. These results support the hypothesis that sex hormones play an important role in the expression of autoimmunity and suggest that estrogens may accelerate autoimmunity in NZB/W F1 mice.
...
PMID:Effect of the anti-estrogen, Nafoxidine, on NZB/W autoimmune disease. 30 24
