Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0033687 (proteinuria)
 24,015 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Mycoplasma pneumoniae pneumonia can be associated with several systemic features. This report illustrates a case of M. pneumoniae pneumonia in an adult who recovered completely. Direct infection of the kidneys or an immunologic mechanism may have been the underlying cause. This patient also had simultaneous pharyngitis caused by group A beta-hemolytic streptococci. Various clinical possibilities with respect to pneumonia, pharyngitis, and proteinuria are briefly reviewed.
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PMID:Pneumonia due to Mycoplasma pneumoniae with transient proteinuria. 1254 2

Increasing insight into the clinical phenotype and mechanisms of SARS-CoV-2 infections and COVID-19 has identified damage of the kidneys as a key player in the course of the disease. This manuscript summarizes the current knowledge on direct viral infection of kidney tissue, proteinuria and acute kidney injury in COVID-19, and management of patients on chronic dialysis as well as after kidney transplantation. Direct infection of podocytes and proximal tubular cells by SARS-CoV-2 has been confirmed and results in proteinuria and hematuria at an early stage of COVID-19. In this context, any kidney affection is a predictor of worse outcomes among COVID-19 patients irrespective of the initial presentation and increases the risk of acute kidney injury. Specific therapies for kidney damage and acute kidney injury within COVID-19 that could be generally recommended are currently lacking. Patients on chronic hemodialysis in particular are at risk for contracting SARS-CoV-2 infections as indicated by outbreaks and super-spreading events in hemodialysis facilities. Immunosuppressive therapy after kidney transplantation needs to be adapted upon diagnosis of COVID-19 depending on the severity of the initial presentation.
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PMID:[COVID-19: The Perspective Of Nephrology]. 3273 Dec 81