Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0033687 (proteinuria)
 24,015 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Urinary schistosomiasis was more frequently observed among subjects aged 10-19 years old; and the degree of exposure to the infection was found to be high among the males. comparative analysis of T. vaginalis infection among the females revealed a 10-fold increase in the detection rate for the flagellate in the urine samples collected from the Special Treatment Clinic than those from the out-patient department. The age- specific morbidity pattern for Trichomonal vaginitis was remarkably high among females of maximum sexual activity (i.e. 20-29 years old); 6 (12.24%) and 4 (8.16%) of the 49 cases of Trichomonal vaginitis had mixed infections with NEisseria gonorrhea and Candida albicans respectively. The association between detection of hematuria, proteinuria and urinary schistosomiasis was supported. Age, sex and social behavior were identified as important determining factors on pattern of genito-urinary parasitic infections. (Author's).
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PMID:Pattern of genito-urinary parasitic infections at the Teaching Hospital, Sokoto, Nigeria. 211 96

A rapid, visually read monoclonal antibody (MoAb)-based dipstick assay for specific diagnosis of urinary schistosomiasis was field tested with microscopy and the use of hematuria and proteinuria in a schistosomiasis hematobia endemic area in Southern Ghana. The study group consisted of 229 individuals (114 males and 115 females) aged 1 to 86 years; 145/229 (63.3%) of the subjects submitted stool samples from which no S. mansoni eggs were detected. However, infections with Necator americanus (hookworms) 33.1%, Ascaris lumbricoides 2.8%, Trichuris trichiura (whipworm) 2.8%, and Strongyloides stercoralis 0.7% were detected but did not appear to influence the results of the MoAb-dipstick assay. Urinary schistosomiasis prevalence was estimated as 47.6% by microscopy, 48% by MoAb-dipstick, 39.7% by microhematuria, and 23.6% by proteinuria. The MoAb-dipstick correctly identified 108/109 (99.1%) of microscopically confirmed cases and 118/120 (98.3%) of egg-negative individuals, thereby giving a sensitivity of 99.1% and a specificity of 98.3%. On the other hand, microhematuria and proteinuria were, respectively, 76.1% and 40.4% sensitive, and 94.2% and 92.5% specific when compared to microscopy. Microhematuria and proteinuria had significantly lower sensitivity (P < 0.001) than either microscopy or dipstick.
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PMID:Limited field evaluation of a rapid monoclonal antibody-based dipstick assay for urinary schistosomiasis. 898 56

Urinary schistosomiasis is caused by the deposition of eggs by adult flukes in the blood vessels surrounding the bladder of the infected host. Schistosomiasis is ranked the second most important parasitic disease of man and undoubtedly the most important of helminth origin. This paper reports the prevalence of Schistosoma haematobium infection among pregnant women in some endemic tropical semi - urban communities of Anambra State, Nigeria, screened using Medi-Test Combi 9 and urine centrifugation methods. Laboratory analysis of urine samples collected from 172 pregnant women indicated that 41 (23.8%) had urinary schistosomiasis with Anam community having the highest prevalence of 35.1% among other communities. The overall prevalence and intensity of infection among age groups showed that the youngest age group in the study, 16-20 years had the highest prevalence. Out of 24 women within this age group, 12 (50.0%) were infected among which 8 (33.3%) had light infection while 4 (16.6%) had moderate infection. The peak mean intensity of 7.6 eggs/10ml urine was observed in age group 16-20 years while the oldest age group, 41-45 years had the lowest mean intensity of 1.0 egg/10ml urine. Haematuria and proteinuria which are diagnostic for schistosomiasis were higher within age group 16-20 years in all the communities with Anam community having the highest prevalence of 50% for both biochemicals within age group 16-20 years. The findings from this study will be useful in developing specific programme for this special group of women.
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PMID:Urinary schistosomiasis among pregnant women in some endemic tropical semi - urban communities of Anambra State, Nigeria. 2320 2

Urinary schistosomiasis causes damage to the urological system. Ultrasound is a method that detects the burden of secondary disease, individually and in epidemiological studies. In this study, the Schistosoma haematobium-associated urinary tract pathology is analyzed before and after treatment in a short period of time. Seventy children who had previously participated in an epidemiological study on schistosomiasis in the city of Cubal, Angola, and had also performed urinary ultrasound between August 2013 and February 2014 were cited 6-8 months later to assess the possible reinfection and repeat new urinary ultrasound, analyzing changes at the level of urinary pathology. The presence of hematuria and proteinuria was also analyzed. Of the 70 children analyzed, 29 (41.4%) were girls, with an average age of 10.4 years (standard deviation 2.3). Fifty-three (75.7%) had an improvement in their bladder and/or kidney scores, whereas 12 (17.1%) had no change and five (7.1%) had progression of the disease. None of the parameters analyzed completely disappeared. After one single course of treatment with praziquantel, all the analyzed parameters showed regression. Improvement was greater in the urinary bladder than in the upper urinary tract, though these lesions also reversed; the reversion of all parameters was greater among children older than 10 years old than the younger ones. Proteinuria was the parameter with a smaller reduction. Ultrasound should be a usual tool for diagnosis and follow-up in urinary schistosomiasis, particularly in children; more accurate recommendations about follow-up in the case of children whose lesions do not reverse should be established.
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PMID:Ultrasound Evolution of Pediatric Urinary Schistosomiasis after Treatment with Praziquantel in a Highly Endemic Area. 3014 96