Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0033687 (
proteinuria
)
24,015
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Diffuse proliferative glomerulonephritis without IgA deposits (DPGN) in patients with
pustulosis palmaris et plantaris
(
PPP
) is described. This association has not been previously reported. Although
PPP
was resolved transiently after tonsillectomy, it was worsened coincidently at the time of exacerbation of DPGN. Improvement of
proteinuria
and
PPP
was observed after antiplatelet therapy. It was suggested that the renal manifestation and the development of
PPP
were associated.
...
PMID:Renal manifestation of pustulosis palmaris et plantaris. 186 81
We examined 24 cases with
pustulosis palmaris et plantaris
(
PPP
) and 13 cases with IgA nephritis. The provocation test was performed in 11 cases with
PPP
and 7 cases with IgA nephritis. According to Nosaka's criteria, as variables for assessing the provocation test, changes in WBC (white blood cell count), BT (temperature), ESR (erythrocyte sedimentation rate) and skin eruption or urinary findings (hematuria and
proteinuria
) were estimated. Analysis of the provocation test proved positive in 3 of 11 cases (27%) with
PPP
and in 5 of 7 cases (71%) with IgA nephritis. Improvement of
PPP
was found in 12 of 14 cases (86%) with tonsillectomy and in 5 of 10 cases (50%) without tonsillectomy. However, there was no significant relation between prognosis and results of provocation tests. Improvement of IgA nephritis was found in 6 of 10 cases (60%) with tonsillectomy and none of 3 cases (0%)) without tonsillectomy. Furthermore, the cases with positive reaction by the provocation test showed better prognosis than those with negative reaction. Our results suggest that in patients with IgA nephritis, the efficacy of tonsillectomy is better in patients with a positive reaction to the provocation test than in those with a negative reaction. However, this phenomenon was not observed in the patients with
PPP
. Improvement of symptoms in the patients undergoing tonsillectomy was found in the early time period after surgery as compared with that in the patients with conservative treatment.
...
PMID:Investigation of the local provocation test to PPP and IgA nephritis. 908 75
