Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0033377 (prolapse)
 11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The fibrinolytic activity in biopsy specimens of superficial veins obtained from postmenopausal women before and after treatment with a nonsteroidal estrogen (P 1496) was determined as well as the coagulation factors antithrombin 3 and components of the fibrinolytic system. Patients were given P 1496, 50 mg/day for 3 weeks before surgery for uterine prolapse. The prothrombin + factor 7 + factor 10 (P and P), factor 8, antithrombin 3, alpha-1-antitrypsin, anti(-2)-macroglobulin, and inhibitors of urokinase induced plasminogen activation were measured. Vein biopsy specimens were taken from the dorsal side of the hand. Fibrinolysis was measured after incubation. The fibrinolytic activity of the specimens was normal and unchanged with treatment.
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PMID:Coagulative and fibrinolytic studies on postmenopausal women treated with a new non-steroidal oestrogen. 7 33