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Query: UMLS:C0033377 (prolapse)
 11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Prolapse of the umbilical cord occurred 69 times in 30112 deliveries. The incidence was higher in abnormal presentations, particularly in compound presentation (11.1%), and in breech presentation (2.9%), especially when these occurred in association with prematurity. Twenty-five (36.2%) of the 69 infants died; 21 of these were dead at the time of diagnosis of cord prolapse, two died in the neonatal period of respiratory distress syndrome, and two died from complications of breech extraction. Reduction in perinatal mortality will be possible only if early diagnosis of cord prolapse can be made by means of vaginal examination or fetal heart monitoring, and the birth trauma associated with difficult vaginal delivery prevented.
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PMID:Prolapse of the umbilical cord: a study of 69 cases. 57 44

Near the end of her first pregnancy, a 17-year-old patient developed sudden epigastric pain followed shortly afterwards by restlessness, paleness and respiratory distress. A diagnosis of pneumothorax was made from the chest radiogram. Shortly after this examination the patient died from cardiocirculatory failure. Autopsy revealed a congenital defect of the diaphragm with prolapse of abdominal organs into the thoracic cavity and displacement of the heart and mediastinum. The strangulated, gas-filled stomach was situated in the thoracic cavity and showed hemorrhagic erosions of the mucosa and a circumscribed mural defect which had obviously developed in the prefinal stage. This case as well as similar ones reported in the literature underline the necessity for a rapid diagnosis of unclear epigastric pain in late pregnancy. In the case of "diaphragmatic hernia" early surgery is indicated.
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PMID:[Sudden maternal death in late pregnancy: congenital diaphragmatic defect causing prolapse of the intestine into the thoracic cavity (author's transl)]. 92 97

The case of a 2-day-old male full-term newborn with myotubular (centronuclear) myopathy is reported. He presented with generalized hypotonia and muscle weakness, swallowing disturbance, and respiratory distress at birth. He had a typical myopathic face, high-arched palate, funnel chest, and mild bilateral ptosis. Deep tendon reflexes were absent. Serum creatine kinase was normal. The histologic examination of the muscle biopsy over the right rectus femoris muscle revealed an increased number of fibers with centrally placed nuclei, type 1 fiber predominance, type 1 fiber atrophy, and a peripheral halo in the sarcoplasm on NADH-TR staining. On electron microscopy, central nuclei were separated by strands of glycogen and mitochondria. His muscle strength showed clinical improvement at a 14-month follow-up. This case illustrates the need for a muscle biopsy and histochemical staining and/or electron microscopic investigation for a proper diagnosis in hypotonic newborns with respiratory distress.
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PMID:Neonatal myotubular myopathy with respiratory distress: report of a case. 168 84

A previously healthy young man sustained a chest injury. During hospital admission following the accident, he exhibited progressive deterioration in blood gases. The chest X-ray showed pulmonary venous congestion. Positive pressure ventilation was required with a tentative diagnosis of respiratory distress syndrome. However, he remained in NYHA class IV. Trans-esophageal cross-sectional echocardiography showed prolapse of the anterior mitral leaflet with papillary muscle rupture. Mitral valve replacement was performed successfully.
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PMID:[Traumatic papillary muscle rupture--a case report]. 196 Apr 42

Listeria monocytogenes can cause sepsis and meningitis during the neonatal period. Six cases of early onset neonatal sepsis caused by Listeria monocytogenes are reported here. These cases were diagnosed in a private hospital at Santiago, Chile from December 1984 throughout November 1986. The incidence rate was 1.4 x 1,000 liveborns. Clinical findings included prematurity (6), meconium stained amniotic fluid (6), hepatomegaly (6), splenomegaly (6), maculopapular exanthem (4), anal prolapse (3) and meningitis (1). Additionally 5 patients developed respiratory distress and 4 required ventilatory support. Overall mortality was 50% (3/6). All deaths were related to respiratory failure and occurred during the first week of disease. All patients received ampicillin and amikacin early in the course of their infection. Listeriosis of the newborn infant might be preventable by prompt recognition and treatment of maternal infections. Since Listeria infection in pregnancy is usually mild and symptoms and signs are nonspecific, prevention may be difficult. Pregnant women with fever of no clear origin or with an influenza like syndrome should be screened for listeriosis with cultures from blood, vagina and cervix samples.
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PMID:[Early onset neonatal septicemia caused by Listeria monocytogenes]. 215 19

Regurgitation of blood through the left atrioventricular valve owing to the rupture of one of the chordae tendineae of the valve was diagnosed in a horse with sudden-onset respiratory distress and a holosystolic cardiac murmur. Severe regurgitation was confirmed with Doppler echocardiography and prolapse of part of the valve leaflet was identified with B-mode ultrasonography. The rupture of one of the chordae tendineae of a right accessory cusp of the left atrioventricular valve was confirmed post mortem. Bronchiolitis, multifocal haemorrhages and haemorrhagic fibrous plaques were found in the pleura of the dorsocaudal segments of the lungs.
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PMID:Confirmation by Doppler echocardiography of valvular regurgitation in a horse with a ruptured chorda tendinea of the mitral valve. 226 Feb 52

The course and outcome of 23 monoamniotic (MA) twin pregnancies, delivered in Tampere University Central Hospital during the years 1964-1984, were studied retrospectively and compared to 1056 diamniotic (DA) twin pregnancies. The frequency of MA twins was 2.1% of twin pregnancies. Polyhydramnion complicated the pregnancy in 26% of MA vs 6% of DA pregnancies. Two cases were defined as acute polyhydramnion. Preterm labour was stated in 70% of MA pregnancies and deliveries before the 34th week were 4 times more common in MA than DA pregnancies. The cesarean section rate was more than double in MA pregnancies (39%). Entanglement of the umbilical cords was noted four times, and prolapse of the cord in three vaginally delivered cases. Perinatal mortality was 28% in MA vs 5% in DA twins. The most common causes of death were respiratory distress syndrome, congenital malformation and feto-fetal transfusion.
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PMID:Monoamniotic twin pregnancy. 375 76

In this study all deliveries with premature rupture of the membranes (VBS) between 1978 and the midst of 1981 were compared and statistically analysed using a control collective, which consisted of the sum of the respective following delivery. A premature rupture of the membranes was found in 18.1 per cent. We observed a VBS more often in case of increasing age of the mother and significantly more often for primiparae. An infection of the urinary tract seemed to increase the risk of an VBS. The latent period is longer, if the VBS occurred in the early pregnancy. There was no difference between both groups according to the course of birth, the frequency of KPDA, the pressing period and the period of dilatation. Complications with the umbilical cord could not be found more often in the collective of premature rupture of the membranes than in the control group. The umbilical cord prolapse even was rarer in case of premature rupture of the membranes. Difficulties in adaptation and the respiratory distress syndrome could be found significantly more often in the group of VBS, according to the higher rate of premature children in this collective. The possible stimulating effect of the VBS on the induction of the fetal lung maturity was reserved by the higher rate of neonatal infections in case of longer latent periods. We found the amnion infection syndrome in 2.1 per cent if the latent period was less than 24 hours, 10.7 per cent if it was longer than 48 hours and more than 15 per cent if it was 72 hours and more.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Clinical aspects of premature rupture of the membranes]. 404 80

Two children, now 5 1/2 and 6 years of age, presented as neonates with hypotonia, multiple joint contractures, ptosis, extraocular weakness, bulbar symptoms, and respiratory distress. Fluctuations and episodic exacerbations of weakness necessitated respiratory support. Both children are developmentally delayed and cannot walk independently, although one child underwent bilateral tenotomies. Biochemical investigations and electromyography, including slow-rate, repetitive nerve stimulation, were normal. Acetylcholine receptor antibodies in serum were absent. Single-fiber electromyography with axonal stimulation revealed prolonged mean jitter in the tibialis anterior and extensor digitorum muscles, with more than 2 abnormal individual jitter values in each muscle. Muscle biopsy demonstrated normal pattern and morphology of muscle fibers; immunohistochemical staining for cholinesterase was positive. Electron microscopy revealed abnormalities in motor endplates: atrophy, flattening of primary synaptic clefts, and paucity of side branches. These findings represent one of the postsynaptic abnormalities (i.e., acetylcholine receptor deficiency or paucity of synaptic folds). Both children improved clinically on pyridostigmine therapy. Arthrogryposis congenital multiplex due to congenital myasthenic syndrome, as diagnosed in our patients, has been reported once before. The diagnosis can be established by clinical history, neurologic examination, and electrophysiologic and pathologic findings. Clinical improvement can be achieved with high-dose anticholinesterase therapy.
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PMID:Arthrogryposis multiplex congenita due to congenital myasthenic syndrome. 761 91

Myasthenia gravis is the most prevalent of the diseases of the neuromuscular junction in children. The most common clinical finding is ptosis, although ophthalmoplegia and facial weakness are commonly present. This paper reports juvenile myasthenia gravis in a 7-year-old boy with predominant facial muscle weakness without ophthalmoplegia and ptosis. This was detected post-operatively after adenotonsillectomy, as there was severe respiratory distress. Prompt diagnosis and treatment was life saving. A CT scan of the chest revealed thymoma. After the surgical removal of the thymoma, the child has been followed up for a year and is asymptomatic.
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PMID:Juvenile myasthenia gravis with predominant facial weakness in a 7-year-old boy. 765 71


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