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Query: UMLS:C0033377 (prolapse)
 11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To review retrospectively hysterectomy specimens sent to the histopathological department of the Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria in order to document the histopathological findings and relate these with the age of patients. The records of patients with hysterectomy specimens sent to the histopathological laboratory within a period of 10 years were studied. Some of the histological slides were reviewed. The diagnosis of uterovaginal prolapse was based on clinical as well as pathological findings. Three hundred and thirty hysterectomy specimens seen over the study period of 10 years were studied. Women aged 40-49 years accounted for the highest number of cases, Hysterectomy was most often performed for leiomyoma (48%). followed by uterovaginal prolapse (17%). In women over the age of 70 years hysterectomy was most often performed for uterovaginal prolapse. Complication of pregnancy still accounted for a high percentage of hysterectomy (11%) Most were ante-partum and post partum haemorrhages as well as septic abortion in young women Ten of the specimens were normal both grossly and microscopically. Six of these were removed for suspected leiomyoma. The peak age incidence for women with leiomyoma who had hysterectomy corresponds with the overall peak age for women who had Hysterectomy. Leiomyoma was the commonest finding in hysterectomy specimens. However, clinicians should ensure that the condition is accurately diagnosed in all cases to avoid removal of a normal uterus.
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PMID:Hysterectomies in Nigerians: histopathological analysis of cases seen in Ile-Ife. 1148 82

Leiomyoma, a benign smooth muscle tumour of uterus, is the most common pelvic tumour which occurs in women of reproductive age group. Uterine leiomyomas are frequently seen in women who are older than 30 years of age and they are very rarely seen in women who are below the age of 18 years. They tend to regress after menopause. Incidence is 4% in women who are below 30 years of age. However , lifetime risk of fibroids in women who are over the age of 45 years is more than 60%, with an incidence which is higher in blacks than in whites Cervical leiomyomas constitute 1-2% of the total leiomyoma cases and they rarely occur. There are three types of cervical leiomyomas, namely; interstitial, supravaginal, and polypoidal. Supravaginal leiomyoma is the commonest type. Large cervical fibroids present with abdominal masses, incarcerated procidentia, uterine inversion, cervical malignancy, etc. The prevalence of fibroids during pregnancy, irrespective of site, has been reported to be 1-4%. Degeneration in leiomyomas have been described in 65% of the cases. Myxoid leiomyoma is characterized by absence of mito tic activity and the presence of myogenic phenotype. The higher end of prevalence for a myxoid degeneration has been reported in upto 50% of all degenerations in uterus, but myxoid leiomyoma has been rarely described in cervix. Cause of a myxoid change in pregnancy is unknown.
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PMID:Myxoid leiomyoma of cervix. 2455 88