Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0033377 (
prolapse
)
11,717
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Pelvic prolapse
has a myriad of clinical manifestations ranging from urethral incontinence to total vault
prolapse
. The evaluation and treatment of these conditions is facilitated by dividing them into three anatomic regions. Anterior vaginal wall
prolapse
is the most common type and includes simple urethral hypermobility as well as severe cystocele. Surgical treatment includes the modified anterior vaginal wall sling, six-corner bladder neck suspension, and formal cystocele repair. Posterior vaginal wall
prolapse
, manifested by rectocele and perineal relaxation, is corrected by plication of the prerectal and pararectal fascia, reconstruction of the levator hiatus, and repair of the perineal body. Vault
prolapse
includes enterocele, uterine
prolapse
, and generalized vault
prolapse
. The choice of treatment depends on the presence of anterior vaginal wall
prolapse
, the degree of vault
prolapse
, and the patient's desire to remain sexually active. It is important to remember that urethral incontinence is only one manifestation of pelvic
prolapse
, and must be treated in conjunction with other
prolapse
to avoid recurrence or poor results.
...
PMID:Transvaginal correction of pelvic prolapse. 874 Mar 84
Pelvic prolapse
affects one woman in three of all ages combined and is quite common for more than 60% of patients over 60 years of age. The treatment of this pathological problem is one of the biggest challenges to the gynaecologist today. The rate of surgical intervention failure is quite significant. The recurrence of
prolapse
could be related to inadequate surgical technique or the pathology or/and biomechanical deficiency of the soft tissues. The modelling and simulation of the behaviour of the pelvic cavity could be a major tool for specific evaluation of pelvic status. A first stage of this model is being developed and reported. The computer-aided design model of the organs of the pelvic floor is created using magnetic resonance image data and the ligament boundary conditions are defined. A multi-organ geometric model is thus created and studied.
...
PMID:Experiments and finite element modelling for the study of prolapse in the pelvic floor system. 2009 69