Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0033377 (prolapse)
 11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Seven cynomolgus monkeys underwent a histologically confirmed left superior cervical ganglionectomy (SCGx). Unilateral ocular sympathetic denervation persisting for at least 2 yr was confirmed by ipsilateral ptosis, miosis, supersensitivity of pupillary dilation to topical phenylephrine, and profound pupillary hyporesponsiveness to topical hydroxyamphetamine. Intraocular pressure 8-9 and 23-27 months postoperatively were identical in the denervated and contralateral control eyes. This model should facilitate studies of aqueous humor physiology and pharmacology.
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PMID:Superior cervical ganglionectomy in monkeys: surgical technique. 173 May 45

In 1978 at the beginning of the modern lens implantation era, 6160 posterior chamber lenses (PCL) were implanted in the USA; 1,110,000 PCL were implanted in 1986. With reference to the total number of lenses implanted, PCL implantations amounted to 4% in 1978 and to 89% in 1986. The increasing use of PCL has mainly been due to the fact that patients with these lenses had significantly better visual acuity and fewer complications after surgery than patients with anterior chamber lenses (ACL). As an example, an FDH study in 1983 should be mentioned: more vision in an otherwise normal eye was more than 0.5: 90% (ACL) versus 94% (PLC); ablatio: 0.9% versus 0.5%; secondary glaucoma: 1.2% versus 0.5%; cystoid edema of the macula: 2.2% versus 0.8%. The considerable advantage in extracapsular extraction of a cataract lies in the fact that the anatomical and physiological conditions of the eye structure may be nearly completely maintained, and this is because the intact posterior capsule--similar to the lens with zonular fibers in the normal eye--forms a diaphragm between the vitreous and aqueous humor. Thus the stability of the eye will be maintained and prolapse of the vitreous with possible traction at the retina cannot occur. Phacoemulsification and ECCE are well-established methods. The clinical results of both methods are practically identical, except for a significantly lower rate of astigmatism with phacoemulsification, which was examined 8 to 10 weeks following surgery (phaco: 1.0 +/- 0.49; expression: 3.3 +/- 1.7).(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Comparative evaluation of intracapsular cataract extraction, extracapsular cataract extraction and phacoemulsification]. 208 93

An eight-year-old female spayed Boston Terrier presented to the North Carolina Veterinary Hospital with glaucoma in the left eye (OS). Initial ophthalmic examination revealed moderate ocular hypertension, a diffusely and markedly shallow anterior chamber with anteriorly displaced iris and lens, vitreal prolapse, and a normal iridocorneal angle (ICA) morphology. The patient displayed a paradoxical response to topical latanoprost with an increase in intraocular pressure. These examination findings led to a putative diagnosis of spontaneous aqueous humor misdirection syndrome (AHMS). The patient was successfully managed with topical carbonic anhydrase inhibitors (CAIs) and apraclonidine for eight months until progressive ulcerative keratitis necessitated enucleation of the affected globe. Histopathology and high-field magnetic resonance imaging (MRI) of the enucleated globe did not identify an underlying cause for the glaucoma. This case suggests that AHMS should be considered in dogs presenting with a shallow anterior chamber, vitreal prolapse, increased intraocular pressure, and no other causes of glaucoma.
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PMID:Suspected Spontaneous Aqueous Humor Misdirection Syndrome in a Boston Terrier. 3255 38