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Query: UMLS:C0033377 (prolapse)
 11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

General anesthetics may have diverse effects on intraocular pressure, possibly leading to serious complications such as vitreous loss and iris prolapse. Clinical and research findings on the effects of depolarizing and nondepolarizing agents are discussed, and methods of avoiding or counteracting adverse reactions are summarized.
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PMID:The effect of general anesthetic agents on intraocular pressure. 33 34

A microsurgical technique for cataract extraction is presented. The operations were performed with a corneal incision and a continuous nylon 10-0 suture. This technique is evaluated by the study of 1289 cases, consecutively operated on. The complication rate was very low. Haemorrhage in the anterior chamber was found in 1%. Delayed reformation of the anterior chamber occurred in only two cases. No cases of iris prolapse occurred. The intraocular pressure was not interferred with by the operation. Wound rupture following removal of the suture three months post-operatively occurred in 1%. The advantages of the corneal incision and continuous nylon suture are discussed (less irritation, good and secure wound closure).
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PMID:Progress in cataract surgery using microsurgical technique. 34 34

During a 7-month period 33 patients (20 with primary open-angle glaucoma and 13 with suspected glaucoma) were treated with guanethidine 3% and adrenaline 0.5% in 1 eyedrop twice daily. The previous therapy was discontinued and the aim of the trial was to treat the patients with GA alone. There was an average decrease in intraocular pressure of 10.8 mmHg or 37.5% for the whole group (including 5 patients with additional therapy). In eyes with an average IOP in a day-curve without medication equal to or higher than 28 mmHg we found a decrease of 44.6% or 14.4 mmHg, and in eyes with an average IOP without medication between 21 and 28 mmHg a decrease of 30.4% or 7.6 mmHg. With GA alone the IOP was 3.3 to 3.9 mmHg lower than on the previous therapy (P less than 0.05); 46% of the eyes without additional therapy had all IOPs lower than 22 mmHg and 74% of the eyes had IOPs lower than 22 mmHg except 1 with a peak lower or equal to 25 mmHg 3 hours after application. This peak 3 hours after application indicates that GA has a biphasic action and was significant at the 0.5% level. Red eyes and slight ptosis were no problem for most patients. Patients found it very convenient to administer GA only twice daily.
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PMID:The combination of guanethidine 3% and adrenaline 0.5% in 1 eyedrop (GA) in glaucoma treatment. 57 58

A total of 80 patients with senile cataract had the anterior eye chamber depth measured optically by means of Haag-Streit's attachment II. The distance to the pupillary border was 2.59 +/- 0.05 mm (mean +/- SEM) preoperatively. It increased gradually after cataract extraction to 3.33 +/- 0.04 mm, measured 4 months after the operation. The increase of depth was the greatest in patients with a flat chamber and in elderly patients. The central chamber depth decreased gradually after the operation (from 2.82 +/- 0.05 mm preoperatively to 1.95 +/- 0.13 mm 4 months postoperatively). The number of vitreous prolapse cases rose from 68 to 87.5% in 4 months. These altered chamber depths were observed to bear no relation to postoperative corneal oedema (neither of parenchyma nor of epithelium), intraocular pressure, or bleeding into the chamber.
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PMID:Depth of anterior chamber after cataract extraction. 67 2

To determine diagnostic value of lens opacities in myotonic dystrophy (DM), we examined 98 at-risk members of 9 DM kindreds. Haplotype analysis of restriction fragment length polymorphisms (RFLPs) using ApoC2, CKMM, and pEFD4.2 supported the diagnosis of DM in 33 and excluded the diagnosis in 51 members. The sensitivities of bilateral iridescent lens opacities, posterior cortical lens opacities, orbicularis oculi weakness, low intraocular pressure, ptosis, and ocular myotonia were 46.7, 50.0, 60.6, 59.3, 51.5, and 3.0%, while their specificities were 100.0, 100.0, 98.0, 94.1, 96.1, and 100.0%, respectively. A peripheral pigmentary degeneration and central macular lesions of retina were not found on indirect fundoscopy. In 86.2% of DM patients, bilateral iridescent lens opacities, posterior cortical lens opacities, or both were present. Unilateral iridescent lens opacities occurred in only 3 of our DM patients, and 2 of non-DM relatives showed a few unilateral iridescent particles. Posterior cortical lens opacities in DM patients always affected both eyes in this series. We conclude that 1) bilateral iridescent lens opacities and posterior cortical lens opacities are highly specific for DM and useful for establishing clinical diagnosis of DM, 2) unilateral iridescent lens opacities are infrequent in DM and are seen in some non-DM members, and 3) ocular myotonia and clinical retinopathies are rare in DM.
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PMID:Diagnostic value of ophthalmologic findings in myotonic dystrophy: comparison with risks calculated by haplotype analysis of closely linked restriction fragment length polymorphisms. 136 51

The results achieved in the treatment of secondary traumatic cataract using either Nd-YAG laser or surgical discussion in 41 patients at the Department of Ophtmhalmology, School of Medicine, University of Zagreb in the period between 1987 and 1989 are presented. Good visual acuity was achieved in 60% of the patients who were treated by Nd-YAG laser, and in 28% of those who had surgical discussion. Transitory increase of intraocular pressure measured 2 hours after Nd-YAG laser application was observed in 90% of the subjects. Transitory increase of IOP correlated negatively with the total amount of the applied laser energy. In 24 hours following surgical discussion no increase of IOP was noted. Postoperative complications of vitreous prolapse and bullous keratopathy were found in 4 patients treated by surgical discussion.
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PMID:[The neodymium YAG laser and surgical discission in traumatic cataracts]. 166 30

The ocular effects of the alpha-adrenoceptor blocking drug bunazosin, administered as eyedrops, have been measured in a placebo-controlled double-blind single-dose study in 15 healthy volunteers. The drug significantly reduced intraocular pressure over 10 hours, and there was no associated change in pulsatile ocular blood flow. Characteristic effects of alpha-adrenoceptor blockade were observed--miosis, ptosis, and conjunctival hyperaemia. The miosis alone persisted for more than 24 hours in nine out of 15 subjects.
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PMID:Ocular responses in healthy subjects to topical bunazosin 0.3%--an alpha 1-adrenoceptor antagonist. 167 67

To prevent vitreous body prolapse in cataract extraction, intraocular pressure is reduced by means of beta-adrenoblockers instillation (timolol 0.5% solution) in the evening and 2 hours before surgery in the morning. Intraocular pressure was followed up in 59 patients with senile and 12 with complicated cataract subjected to cataract cryoextraction by the same surgeon. The pressure decreased by 5.6 +/- 1.3 mm Hg. Prolapse of the vitreous body occurred in 1 case.
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PMID:[Use of beta adrenergic blockaders in the prevention of vitreous body prolapse in cataract extraction]. 167 3

We investigated the effects of the topical application of acepromazine maleate on the intraocular pressure (IOP) in 27 adult rhesus monkeys. The monkeys were divided into two groups: group 1 (16 monkeys) had both eyes normal, and group 2 (11 monkeys) had experimental chronic glaucoma in one eye and a normal fellow eye. One drop of 1% acepromazine maleate solution was instilled in one eye of monkeys in group 1 and in the glaucomatous eye of monkeys in group 2; the other eye served as the control. The IOP was measured before drug administration and 1, 4, 8, 24, and 32 hours after, with detailed slit-lamp examination of the anterior segment. Acepromazine produced no change in IOP in eyes in group 1, but it produced a fall in pressure in all eyes with high IOP in group 2, evident 1 hour after instillation, maximal between 4 and 8 hours, and still remaining after 32 hours. The pupil showed no change in size, but a transient ptosis was observed in the treated eye in all monkeys.
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PMID:Acepromazine. Effects on intraocular pressure. 198 28

A retrospective study of cataract surgery performed between January 1983 and December 31, 1989, disclosed 48 eyes in which the posterior capsule was torn. The overall incidence of this complication was approximately 1% but was further reduced when the technique of capsulorhexis was mastered. Our review of the video tapes of these surgical procedures revealed that the tear occurred most frequently during nucleus removal (41%) and posterior capsular vacuuming (28%). The anatomy of each tear was classified and related to the event responsible for the torn capsule, as well as to the likelihood of vitreous involvement. Vitreous presented through the tear in 32% of the 48 cases, entered the wound in 6%, and remained posterior to the torn capsule in 62%. Intraocular lenses were implanted in every case; only posterior chamber lenses were used during the last four years of the study. Vitreous-related complications included vitreous prolapse, peaked pupils, and vitreous-induced pupillary block. Acute postoperative intraocular pressure elevation was a frequent finding and was managed by conservative therapy. Transient cystoid macular edema developed in one case which had a rotating anterior chamber intraocular lens. No retinal detachments occurred in this series. Final visual acuity of 20/40 or better was achieved in 89% of the 48 cases. When properly managed, a torn posterior capsule is compatible with an excellent visual outcome.
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PMID:The torn posterior capsule: its intraoperative behavior, surgical management, and long-term consequences. 238 Sep 32


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