Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
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Drug
Enzyme
Compound
Query: UMLS:C0033377 (
prolapse
)
11,717
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Concealed quadrigeminy has been observed in a 24-year-old pregnant woman without apparent heart disease during 10-hour Holter monitoring; in a 33-year-old female with
prolapse
of the mitral valve during 0.5-hour continuous electrocardiographic recording, and in an 80-year-old man with
anterior myocardial infarction
. In all these continuous electrocardiographic recordings 391, 437, 25 consecutive interectopic intervals were correlated and the number of sinus beats in each interval fitted the formula s=4n - 1. The 2nd case showed a variant of concealed quadrigeminy. The number of sinus beats in 9 interectopic intervals fitted the formula s=4n when the first ectopic beat of the interval was interpolated and did not interfere with the propagation of the next first sinus beat.
...
PMID:Concealed quadrigeminy. 616 78
Contradictory two-dimensional echocardiographic findings have been reported in relation to the role of
prolapse
of the mitral valve and lack of systolic leaflet coaptation in mitral regurgitation secondary to coronary heart disease. A prospective study of 22 patients with chronic coronary heart disease and mitral regurgitation showed the following: Inferior akinesia was detected in 14 (64%), fibrosis of the postero-medial papillary muscle in 10 (45%), and
prolapse
of the mitral valve in nine (41%). A combination of the three signs was seen in six patients (27%). Lack of systolic leaflet coaptation was seen in only two patients, both with
anterior myocardial infarction
. When these results are compared with those reported in the literature, it is apparent that in acute coronary heart disease, lack of leaflet coaptation is frequently visualized (P less than 0.01) and fibrosis of the postero-medial papillary muscle and
prolapse
of the mitral valve are lacking (P less than 0.01). A unitary explanation of all forms of mitral regurgitation in coronary heart disease is misleading; mechanisms of mitral regurgitation in coronary heart disease depend on the clinical presentation--acute or chronic, the site of infarction, and the presence of cardiac dilatation.
...
PMID:Different mechanisms of mitral regurgitation in acute and chronic forms of coronary heart disease. 664 50
