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Query: UMLS:C0033377 (prolapse)
 11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Circular prolapse of the urethral mucosa in the elderly female is rarely reported in the literature, but is a common clinical entity. During the years 1972-1983 thirteen women with urethral prolapse were operated upon in our department, in all of whom differentiation of the benign lesion from malignancy could not be done on clinical grounds only. The following survey is meant to draw attention to the entity and its clinical implications.
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PMID:Strangulated prolapse of the urethra in the elderly female. 286 36

During the last 19 years 40 girls with urethral prolapse have been seen at our medical center. Treatment has ranged from nonoperative approaches to excision of the prolapsed urethra. A comparison of the treatment modalities indicates that patients undergoing early local excision of the prolapse have the lowest complication rate and shortest hospital stay.
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PMID:Treatment of girls with urethral prolapse. 654 Aug 15

Urethral prolapse denotes the complete circular eversion of the urethral mucosa through the external meatus. Two different entities exist: premenarcheal and menopausal urethral prolapse. Premenarcheal prolapse is predominantly asymptomatic and is usually brought to medical attention by vaginal bleeding. Trauma and medical conditions predisposing a patient to increased abdominal pressure are associated with prolapse in children. The menopausal group seeks medical attention primary because of the severity of urinary symptoms, ie, nocturia, urgency, tenesmus, dysuria, and frequency. Therapy for both groups has been traditionally accomplished by surgical manipulation-excision, surgical ligation, cautery, fulguration, and cryosurgery. The authors treated 5 premenarcheal female children with antibiotics, estrogen cream, and sitz baths for 2 weeks. In all the patients prolapse was resolved. The results, with follow-up for 4 to 12 months without recurrence, suggest that urethral prolapse in children can be managed without surgical intervention.
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PMID:Medical treatment of urethral prolapse in children. 707 52

Total prolapse of the urethral mucosa in women is an uncommon lesion, observed at the two extremes of reproductive life. Strangulation of urethral prolapse is a rare complication whose emergency treatment is essentially surgical. The authors report a case of strangulated urethral prolapse in a 43-year-old woman, for which several pathophysiological mechanisms can be proposed: first delivery by forceps, poorly repaired perineal tear, untreated early menopause at the age of 40 years. Urethral prolapse in elderly women has become much less common since the introduction of hormone replacement therapy for menopause. Other physiopathogenic factors may be responsible for this prolapse, such as thrombosis of the juxtameatal submucosal veins, laxity between the mucosa and submucosa or uretrodetrusor dyssynergia. The diagnosis of strangulated urethral prolapse is based on the discovery of a very painful, violaceous, inflammatory circular mucosal tumour surrounding the urethral meatus. If rapid reduction of the prolapse is not obtained with systemic and topical oestrogen therapy, the strangulated mucosal flap must be resected surgically, followed by apposition of the urethral mucosal and submucosal planes. This suture, in tissues which are always inflamed, must be calibrated and the urine must be drained by bladder catheter for about ten days. Meatal stricture is the principal complication of this surgery.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Strangulated urethral prolapse in a young woman: a rare urological emergency]. 787 77

We report our experience with 23 girls with urethral prolapse. Vaginal bleeding was the most common complaint, and predisposing factors (cough, trauma, and constipation) were found in 10 children. Although reported almost exclusively in black girls, 14 of the 23 patients were white. Three basic techniques were used for therapy: conservative management, ligation over a Foley catheter, and total excision of the prolapse. Ligation over a Foley catheter had a high incidence of complications (partial recurrence, infection, postoperative pain) and is no longer used. The best results were obtained by complete excision of the urethral prolapse. We propose that treatment should be based on the etiopathogenesis of the prolapse and the clinical condition of the child; patients with a single and acute episode of increased abdominal pressure, such as trauma, and those at high risk for general anesthesia are managed by conservative therapy. All others, and patients who fail medical treatment, undergo surgical excision.
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PMID:Urethral prolapse in children. 844 6

In the 15 years from 1981, 58 white girls were treated for urethral prolapse. They were grouped into those with partial prolapse (n = 17) and those with circular prolapse (n = 41). Medical treatment was successful in 20 patients with 5 recurrences, 2 of whom ultimately required operation. Lack of response to medical treatment resulted in a further 38 patients undergoing surgery. Four girls had complications: bleeding (n = 1) urethral stenosis (n = 2) and recurrence (n = 1). These complications were treated successfully. Pathological changes in prolapsed urethral mucosa are discussed in this report.
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PMID:Prolapse of urethral mucosa in white female children: experience with 58 cases. 909 8

Urethral prolapse is an uncommon condition affecting young male dogs, most commonly English bulldogs. Current described techniques for surgical treatment of urethral prolapse involve manual reduction of prolapsed mucosa and placement of a temporary purse-string suture at the penile tip, or resection of the prolapsed tissue and apposition of urethral and penile mucosa. The incidence of recurrence of urethral prolapse following resection of the prolapse is not known. This report describes a technique for surgical treatment of urethral prolapse in the male dog that minimizes surgical and anesthetic time, is simple to perform, requires minimal equipment, is effective, and is not associated with significant complications or recurrence. Three cases are described.
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PMID:A urethropexy technique for surgical treatment of urethral prolapse in the male dog. 1211 92

A 67-year-old woman who had failed two prior anti-incontinence surgeries presented with stress urinary incontinence and intrinsic sphincteric deficiency. Calcium hydroxylapatite (Coaptite(R)) was injected cystoscopically into the bladder neck and proximal urethra and resolved her incontinence. Seven months later, she presented with difficulty in voiding and a urethral mass. Physical examination revealed a large prolapse of the urethral mucosa obstructing the external urethral meatus. Surgical exploration revealed local migration of calcium hydroxylapatite particles from the site of injection (bladder neck and proximal urethra) to the distal urethra. The prolapsed urethral mucosa was incised and marsupialized. Improper injection techniques likely contributed to urethral prolapse in this complication. Meticulous attention to injection techniques is the key to treatment success of urethral bulking agents, particularly in patients who have a scarred/fixed urethra or have multiple urethral/vaginal surgeries.
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PMID:Large urethral prolapse formation after calcium hydroxylapatite (Coaptite) injection. 1841 66

We describe the novel management of a 68-year-old postmenopausal woman with urethral mucosal prolapse, stress urinary incontinence, and significant pelvic organ prolapse. Successful surgical management of her urethral prolapse was achieved using a retropubic suburethral sling with urethral fixation at the time of anti-incontinence and pelvic reconstructive surgery.
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PMID:Novel approach for correction of urethral prolapse using a retropubic sling with urethral fixation. 1919 53

A 5-year-old girl of Ghanaian origin presented to the accident and emergency department with genital bleeding of sudden onset in the previous 12 h. A diagnosis of urethral prolapse was made. The congestion and bleeding settled with a daily sitz bath and topical oestrogen cream for 4 weeks, while the prolapse was referred to urologists.
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PMID:Genital bleeding. 2270 20


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