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Query: UMLS:C0033377 (prolapse)
 11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a series of 24 patients with Turner's syndrome, amblyopia was found to be present in ten (41.6 per cent), strabismus in nine (37.5 per cent), hypermetropia in ten (41.6 per cent), ptosis in seven (29.1 per cent), and bilateral epicanthus in eleven (45.8 per cent) cases. Turner (1938) described a syndrome of infantilism, congenital webbed neck, and cubitus valgus, which has come to be known as Turner's syndrome. Since then many cases have been reported and multiple other associated features have also been recognized. Isolated ocular features have been mentioned in some sporadic case reports (Cunningham and Harley, 1951; Laurent, Royer, and Noel, 1961; Lessell and Forbes, 1966; Khodadoust and Paton, 1967; Szymanska and Szymanski, 1976; Troupe and Troupe, 1981). So far no significant series of cases has been studied to assess the ocular defects. This report of a series of 24 patients presents classified ophthalmic features.
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PMID:Ocular manifestations of Turner's syndrome. 696 61

The paper describes Kearns-Sayre's syndrome, a rare hereditary neuromuscular disease, in a patient aged 17 years. The clinical picture of the disease had a classical triad: external ophthalmoplegia, pigmentary retinopathy, and cardiac conduction disturbances. This triad was supplemented with other polymorphous symptoms characteristic of the syndrome, such as moderate myopathic syndrome, hemeralopia, physical infantilism, hypogonadism, pyramidal syndrome. Bifascicular block in the His-Purkinje system was accompanied by mitral prolapse. The problems of early diagnosis of the syndrome and choice of adequate therapeutical methods are discussed.
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PMID:[The Kearns-Sayre syndrome]. 815 11