Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0033377 (prolapse)
11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors compared the agreement between clinical, radiological and surgical diagnoses in 33 cases of nucleus pulposus prolapse. A complete agreement of diagnoses was obtained in 88% of cases. The mechanism and incidence of different signs and their importance for the diagnosis of nucleus pulposus prolapse are discussed. It should be stressed that the compression of nerve roots recognized on radiculography is not pathognomonic sign of prolapse and may be due to such processes as development of marginal osteophytes in the degenerative disc disease, thickening of the posterior longitudinal ligament, hypertrophy of radicular processes or necks of vertebral arches. In the light of own experiences and data from the literature the authors consider radiculography with Amipaque and computer tomography as the method of choice in cases with suspected disc herniation in the lumbar region.
...
PMID:[Diagnostic recognition of nucleus pulposus prolapse in light of clinical and radiologic correlations]. 167 28

The lumbar spine magnetic resonance (MR) studies in 246 consecutive patients who suffered from persistent back and leg pain were evaluated for the degree of degenerative disc disease and the presence of disc bulging, prolapse, or herniation. No patient had a history of previous back surgery. In those patients, degenerative disc changes increased with age until the fifth decade of life, after which a relatively similar proportion of patients had degenerative disc disease. Significant dehydration and degeneration occurred in less than 5% of the upper two disc spaces while L4/5 and L5/S1 had marked changes in greater than 20%. Prolapse and herniation progressively increased with each lower interspace, where at L5/S1 it was present in nearly one-third of the patients. Although a few patients had disc prolapse or herniation with a nondegenerated disc, there was a relationship between the presence of disc degeneration and prolapse or herniation.
...
PMID:Magnetic resonance assessment of the distribution of lumbar spine disc degenerative changes. 285 24

A 31-year-old man with cervical degenerative disc disease was seen at an outside institution for a right selective nerve root block at C7. Following the procedure, he had right ptosis and miosis. Pharmacologic testing confirmed a right Horner syndrome. MRI and MRA showed no arterial dissection. This report documents the unusual occurrence of permanent Horner syndrome following a selective cervical nerve root block.
...
PMID:Horner syndrome following a selective cervical nerve root block. 2084