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Query: UMLS:C0033377 (prolapse)
 11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors submit the results of clinicoechocardiographic investigations of 35 patients with beta-thalassemia aged from 4 to 37 years of whom 23 patients were with acute beta-thalassemia, 6 with an intermediary form and 6 with a heterozygotic form of the disease. Various echocardiographic changes were observed in patients with acute and intermediary forms of beta-thalassemia, i.e. prolapse of the mitral valve (52 and 50 per cent), the presence of fluid in the pericardium (13 and 17 per cent), structural changes in the valvular apparatus (56 and 83 per cent), disorders of the inotropic and diastolic functions of the heart.
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PMID:[The echocardiographic characteristics of cardiac lesions in beta-thalassemia]. 221 58

Here, we present the first instance of Guillain-Barre syndrome variant in a patient with beta thalassemia and iron overload who had a history of transfusion before the onset of symptoms. Our patient was a 50- year-old Persian woman with history of intermediate thalassemia who had been treated with pack cells because of low hemoglobin level. Ten days after transfusion, she developed numbness of arms, left sided ptosis, and afterwards dysarthria, dysphagia, and bilateral ptosis. Electrodiagnosis on day 12 revealed reduced repetition of f-waves in the upper limbs and reduced recruitment with 1+ fibrillation in facial muscles. Electromyography and nerve conduction velocities in the limbs were normal. After excluding other causes and according to electrodiagnosis, the pharyngeal-cervical-brachial variant of Guillain- Barre syndrome was considered and plasma exchange began. Following exchanges, significant clinical improvement was attained. Iron overload and possible transmission of infections from blood products might have contributed in the development of syndrome.
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PMID:Pharyngeal-cervical-brachial variant of Guillain-Barre syndrome in a patient with thalassemia intermedia. 2104 78