Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0033377 (prolapse)
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A 70-year-old man presented with proptosis and ptosis of the right eye. An orbital mass was palpable and computed tomography scanning and magnetic resonance imaging scanning confirmed its superior orbital position, with extension back to the orbital apex. Definitive biopsy, undertaken via an anterior orbitotomy, demonstrated the lesion to be Kimura's disease. The patient was managed conservatively, and most of his symptoms resolved. Kimura's disease involving the orbit is briefly reviewed in this paper.
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PMID:Kimura's disease of the orbit. 315 45

A 23 year female presented with bilateral recurrent swelling of eyelids along with ptosis and proptosis for last 3 years. She also had swellings over the right cheek, parotid gland, and retro auricular area along with regional lymphadenopathy. Systemic laboratory workup revealed raised serum IgE and a high peripheral eosinophil count. Computed tomography and magnetic resonance imaging showed bilateral enlargement of extraocular muscles, lacrimal glands, and ipsilateral parotid gland. Excision biopsy of the retro-auricular lymph node was suggestive of Kimura's disease (KD). The patient responded well to systemic corticosteroid. KD rarely affects orbit, but it should be included in the differential diagnosis of inflammatory diseases of the orbit. To our knowledge, this is the first reported case of KD from India involving the orbit, lacrimal gland, extraocular muscles, parotid gland and buccal area.
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PMID:Kimura's disease involving bilateral lacrimal glands and extraocular muscles along with ipsilateral face: A unique case report. 3175 77