Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0033377 (
prolapse
)
11,717
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
One hundred and twenty-seven patients with complete rectal prolapse have been reviewed. The condition occurred more commonly in females than males (105 to 22), and at an older age in females (mean age 55 years compared with 40 years for males). Although the diagnosis is usually obvious, the importance of recognizing occult
prolapse
is stressed, especially in association with benign rectal ulcer, localized
proctitis
and colitis cystica profunda. Examination of the patient in the squatting position may assit in showing occult
prolapse
. Associated incontinence occurred in 33 patients (26%). Since 1971 the policy of this Unit has been to perform a Ripstein repair for complete rectal prolapse wherever possible. One hundred and two Ripstein repairs have not been performed. A minimum follow-up period of two years is available for 53 patients, of whom 50 (94%) have had their
prolapse
cured. Control of
prolapse
usually improves continence; however, seven (13%) remained incontinent despite surgery. The Ripstein repair is strongly advocated as the most effective operation for cure of complete rectal prolapse.
...
PMID:Rectal prolapse. 28 34
A series of 164 patients with
procidentia
recti has been studied. Symptoms are sensation of obstruction, difficulties in emptying the bowel,
proctitis
, incontinence, reduced tonus of anal sphincters, and complete rectal prolapse. During I the rectum prolapses only under increased intraabdominal pressure and retracts spontaneously. Massive
prolapse
(stage II) often occurs without increased intraabdominal pressure and has to be reposited manually. Best results are obtained by fixing the mobilised rectum in the hollow of the sacrum as described by Wells in 1959 or by Ripstein in 1969. In bad risk patients a sublevatoric wire can be used. Most patients have satisfactory continence postoperatively without a corresponding physiological tonus of anal sphincters.
...
PMID:[Rectal prolapse. Clinical studies on rectal prolapse]. 55 78
Rectopexy associated with anterior prolepsectomy was performed for 22 patients (19 females, 3 males), with solitary rectal ulcer syndrome (SRUS) surrounding internal rectal prolapse. The different lesions of SRUS were distributed among 3 main groups (G) according to the macroscopic appearance: G1: solitary ulcer (n = 7); G2: ulcerated
proctitis
(n = 7); G3: muco-hemorroidal
prolapse
(n = 3). A significant difference (P less than 0.05) was observed between each group, concerning mean age (G1: 34 years, G2 = 49, G3: 65) and the degree of perineal descent, which was more important in G3 and G2. Posterior intersphincteric rectopexy was performed for 6 patients in G3, with descending perineum and faecal incontinence, treated in the same time by perineoplasty (Parks). Abdominal rectopexy, mainly by the antero-posterior technique (Nicholls), was performed for the other patients (n = 6). Large anterior prolapsectomy reaching the top of the mucosal
prolapse
(4-7 cm), allowing ulcer resection in 3 cases, was combined with rectopexy. Associated operations were: sphincterotomy (n = 8) for narrow fibrous anal canal, sigmoidectomy (n = 4) for dolichocolon. Mean healing time for the solitary ulcer group (G1) was 2 months, 1 month for lesion of G2 and G3. Failures concerned 1 solitary ulcer after abdominal rectopexy and 1 ulcerative
proctitis
after rectopexy without prolapsectomy. Anorectal pain (81%), rectal bleeding (76%), faecal incontinence (27%), straining (81%), were cured or improved in 80% of cases. These results tend to confirm the efficacy of rectopexy, specially using the antero-posterior technique, for the treatment of SUSR with internal rectal prolapse. Nevertheless, rectopexy seems to be insufficient to correct the mucosal component of internal rectal prolapse, bearing the ulcerated lesion which needs to be treated by associated anterior prolapsectomy. Similarly all functional or organic disorders involving the perineum, anal canal or colon leading to anorectal dysfunction must also be considered to ensure complete treatment.
...
PMID:[Solitary rectal ulcer syndrome: clinical features, clinical course and treatment. Apropos of 22 cases]. 210 Jan 20
Our study involved a group of 46 cases of isolated rectal ulcer syndrome. We believed that our management procedure would have to take several factors into consideration. Firstly, the clinical context is of primary importance: the age, psychological context, functional signs and, above all, the state of the lesions. We attached particular importance to distinguishing between the forms of
proctitis
(whether ulcerated or not) and the pseudotumoral polypoid forms. In addition, complementary explorations (dynamic rectography and anorectal manometry) can provide valuable information (the degree of
prolapse
, impairment of the exoneration mechanism and the status of sphincter function). In both ulcerated and non-ulcerated forms of
proctitis
, the treatment is essentially medical and intended to treat the constipation and rehabilitate the exoneration. This treatment suffices in most cases. In poorly tolerated cases, involving persistent bleeding or in forms corresponding to major
prolapse
, surgery is required which usually includes proctopexy. The first problem posed by pseudotumoral polypoid forms is that of a differential diagnosis to formally exclude cancer or an inflammatory disease process. Transanal biopsy exeresis may be crucial in the diagnosis. In addition, this transanal resection may well initiate therapy, in combination with medication. In some forms, involving major
prolapse
, it is logical to combine rectopexy. In some cases, rectopexy may be necessary if simple transanal resection is unsuccessful (persistence or recurrence of lesions). Rectopexy is also frequently the only treatment possible of pseudotumoral forms affecting extensive areas or higher regions of the bowel.
...
PMID:[Treatment of isolated rectal ulcer syndrome]. 237 19
Forty-five patients with soiling but without faecal incontinence were evaluated by means of anorectal function investigations (anal manometry, rectal capacity and saline infusion test). The causes of soiling and the effect of treatment on both soiling and anorectal function were studied. The results were compared with a control group of 161 patients without soiling or incontinence. The diagnoses were haemorrhoids (10), mucosal
prolapse
(7), rectal prolapse (6), fistulae (5),
proctitis
(3), faecal impaction (2), rectocele with intussusception (2), scars after fistulectomy (2) and others (8). Simple inspection and proctoscopy were generally sufficient to establish a diagnosis. For two patients the diagnosis rectocele was made after defaecography. Anorectal test results did not differ between the soiling and control group, did not contribute to establish a diagnosis and did not change after treatment. Only patients with a rectal prolapse had abnormal results in anorectal function tests: a low basal sphincter pressure and a limited continence reserve. Appropriate therapy resulted in complete recovery (44%) or improvement of symptoms (29%).
...
PMID:Soiling: anorectal function and results of treatment. 270 80
Manometric studies of internal sphincter responses were carried out on 15 patients--14 with rectal prolapse and one with mucosal
prolapse
with
proctitis
cystica profunda. In all 12 patients studied preoperatively, the internal sphincter reflexes (inhibitory reflex) were absent or markedly obtunded. Anterior resection was performed on three of the patients in whom preoperative and postoperative manometric studies could be carried out. In one, the inhibitory reflex returned to normal after successful corrective surgery and in one, absence of the reflex persisted after anterior resection and this patient eventually had recurrent rectal prolapse.
...
PMID:Manometric studies in rectal prolapse. 646 87
Proctitis
cystica profunda is an uncommon benign rectal condition with a range of appearances that has led to confusion in nomenclature. In a personal series of 28 patients with histologically proven
proctitis
cystica profunda, over 50 per cent had associated rectal prolapse. Cure of the
prolapse
cured the
proctitis
cystica profunda in 80 per cent of the patients only. Direct surgical excision (local or segmental) has not been successful and two patients have required a stoma for relief of pain.
...
PMID:Proctitis cystica profunda. Incidence, etiology, and treatment. 669 41
Reports of cases of primary and secondary syphilis are increasing in the United States, particularly in urban areas and among homosexual men. While primary syphilis poses little diagnostic difficulty, many physicians are unfamiliar with the multisystem nature of secondary lues. Patients who have secondary syphilis commonly present with systemic signs, skin rash, mucous membrane lesions and generalized adenopathy. Less commonly, secondary syphilis may occur as acute meningitis, sensorineural hearing loss, iritis, anterior uveitis, optic neuritis, Bell's palsy, gastropathy,
proctitis
, hepatitis, pulmonary infiltration, nephrotic syndrome, glomerulonephritis, periostitis, tenosynovitis and polyarthritis. The diagnosis of secondary syphilis is easily confirmed. Its various manifestations are readily treated with penicillin and, if treated early, are entirely reversible. Two recent cases of secondary syphilis, one presenting as nephrotic syndrome and one as chorioretinitis and
ptosis
, illustrate the usual and unusual features of this common infection.
...
PMID:Secondary syphilis: uncommon manifestations of a common disease. 670 90
In line with the literature, the authors consider that solitary ulcer of the rectum, either isolated, multiple or histological, like suspended
proctitis
, inverted hamartomatous polyp, deep cystic colitis, is a complication of rectal prolapse, which usually shares the same clinical symptoms. Solitary ulcer of the rectum is generally discovered on proctoscopy and is due to the strain exerted on the rectal mucosa by 2 opposing forces:violent effort of defecation against an anal and/or perineal obstruction. The reduction of these pressure and counterpressure forces with age and progressive alteration of the pelvic floor accounts for the progression of acute lesions towards chronic or attenuated lesions or even complete resolution. The therapeutic strategy should therefore decrease trauma by facilitating defecation by a combination of hygiene and dietary advice and biofeedback retraining, and surgical reduction of the anal obstruction and
prolapse
and correction of any perineal insufficiency.
...
PMID:[Solitary ulcer of the rectum]. 819 3
Endoscopic ultrasound (EUS) was designed for the evaluation of malignancies; however, its utility has been extended to the assessment of benign disorders, which include inflammatory bowel diseases. Topics discussed in this article include instruments and methods, EUS images in various inflammatory diseases, clinical severity and EUS typing, endoscopic grading of inflammation and EUS typing, extent of disease involvement and EUS typing, response to therapy and EUS typing, changes in EUS findings by treatment, Crohn's disease, radiation
proctitis
, ischemic colitis, tuberculosis, and mucosal
prolapse
syndrome.
...
PMID:Endoscopic ultrasonography in inflammatory bowel diseases. 853 34
1
2
Next >>