Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0033377 (prolapse)
 11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Six hundred and twenty-one hysterectomies were performed at National Women's Hospital, Auckland, during 1975. Abnormal vaginal bleeding was the clinical indication in 50.72% of the cases. Fibroids, pelvic mass, prolapse, stress incontinence and cervical neoplasia were the indication for 45.88% of the cases. Total hysterectomy was performed in 618 (99.5%) patients whilst sub-total hysterectomy was done in only three cases. Histopathological studies revealed that 567 (91.30%) specimens were pathological and there was multiple pathology in 55.87% of the specimens. Leiomyomas were present in 278 cases (44.76%); microleiomyomatosis in 178 specimens (22.66%); endometrial hyperplasia in 139 specimens (22.33%) adenomyosis in 87 cases (14.00%); malignant diseases in 76 cases (12.23%); and endometriosis in 40 specimens (6.44%). There were no histological abnormalities in 54 specimens, 8.69% of this series.
 ...
PMID:The pathology of hysterectomy specimens. 28 33

A vast literature reports on the ability of some tumor tissues to preserve the receptorial system of the original cells, which can be an indication of hormonal dependence of tumors. The authors tried to determine in quantitative term the receptorial capacity of beta Estradiol 17 of the normal and of the pathological endometrium. 23 postmenopausal patients were investigated, 10 with adenocarcinoma of the uterus, 6 with uterine fibroleiomioma, 4 with genital prolapse, and 3 with recurrent metrorrhagia. The maximal receptorial concentration was found in the 10 patients with adenocarcinoma, with concentrations going from 39.8 to 86.3 femtomoli/mg proteins. The normal value of a normal endometrium would be from 22 to 60.2 femtomoli/mg proteins. Some hypotheses are advanced about the receptorial capacity of the pathological tissues studied.
 ...
PMID:[17-beta estradiol receptors in the normal and pathological human uterus]. 42 39

Cartilaginous tumors arising from the skull or intracranial structures are infrequently seen. There have been 112 such cases reported. They are most commonly found in the middle fossa and the parasellar region. They arise from cartilaginous rests in the base of the skull, particularly around the basal synchondroses. Occasional cases of intracranial growths also show lesions in peripheral bones. The authors have encountered a case in which chondroma was a manifestation of generalized chondromatosis. The patient was a 25-year-old male, who complained of diplopia in May 1975. He noted ptosis in his left eyelid which gradually progressed over a 2 months period to complete ptosis. When he was admitted in July 1975 to Nagoya National Hospital, the neurologic signs revealed a palsy of the IIIrd cranial nerve on the left side. The patient has been suffering from generalized enchondromatosis during a period of 20 years. Roentgenograms revealed extensive areas of bone destruction and pathological calcification of the phalanx, ribs, hip bone, femur, tibia, ulna and radius. Roentgenograms of the skull revealed calcification on the left middle fossa. After a left carotid angiography, an osteoplastic craniotomy was performed on August 5, 1975. The tumor was located in the extradural space of the middle cranial fossa. After incision of the capsule, gelatinous semisolid tissue was removed piecemeal. Its total removal proved to be impossible. Histological examination of this tumor revealed enchondroma.
 ...
PMID:[A case of enchondroma of the skull base--a manifestation of generalized chondromatosis (author's transl)]. 55 59

Based on the study of the causes of rehospitalization of 323 patients. Previously operated upon for rectal cancer, it was found that 91 patients developed late postoperative complications, 96 - recurrences, 45 - distant metastases and 51 - metachronous tumors. Among surgical complications colostome strictures in the anal region (37), mucosa prolapse (26) and paracolonic fistulas (23) were most frequently observed. The analysis of treatment for tumor recurrences (96) and distant metastases (45) indicated that surgical excision seems to be mostly effective as a radical procedure. The effect of electrocoagulation in recurrences is somewhate inferior to surgery but still it is appreciable enough. The use of irradiation, chemotherapy, palliative operations fails to produce any appreciable effect on patients' lifeterms.
 ...
PMID:[Results of treating the late complications of patients radically operated on for rectal cancer]. 65 70

Prolapse of the gastric mucosa into the duodenum must be considered when a round soft tissue mass is seen in the right upper quadrant on scout abdominal film. Gastric prolapse may mimic tumor in the duodenum when the prolapse is large. Examination with barium meal is necessary to exclude prolapse of the gastric mucosa into the duodenum as a cause of epigastric pain and vomiting. Medical treatment is suggested for patients with mild symptoms, but patients with severe symptoms, repeated hemorrhage, anemia, severe intermittent epigastric pain and vomiting due to ball-valve syndrome should have operation.
 ...
PMID:Duodenal pseudotumor with ball-valve syndrome. 72 37

Metastatic tumor occurred in the right orbit of a 50-year-old woman 5 years following bilateral mastectomy. The tumor caused enophthalmus, ptosis and restriction of the ocular movements. The tumor consisted of nondifferentiated cells. Transmission and scanning electron microscopic appearance of the tumor is also reported.
 ...
PMID:Metastatic tumor of the orbit. 120 May 57

An accurate diagnosis of cardiac pathology using TEE is contingent upon the ability to recognize and differentiate normal cardiac structures and normal variants from pathologic conditions. We describe several normal cardiac structures commonly imaged using TEE of the atria, interatrial septum, aorta, valves, and extracardiac spaces that may mimic diverse pathologic states, such as intracardiac tumor and thrombus, valvular vegetations, mitral and tricuspid valve prolapse, atherosclerotic plaque, and aortic dissection. Methods to aid in the differentiation of normal cardiac structures from pathology are offered.
 ...
PMID:Transesophageal echocardiography: normal variants and mimickers. 826 87

Extracerebral cavernous hemangioma is a rare entity, only 51 cases have been reported up to 1991. Most of the extracerebral cavernous angiomas occur in the parasellar region and easily extend to the sella; with CT and MRI views entirely different from those of intracerebral cavernous hemangiomas. The CT scan shows a good, homogeneous enhanced tumor, similar to a meningioma, yet lacking calcification or bony hyperostosis. In MRI, the characteristic findings of extracerebral cavernous hemangioma are the very high signal intensity in the T2 weighted image, and strong homogeneous enhancement by Gadolinium-DTPA. Here we report two cases of parasellar cavernous hemangioma. A 68-year-old male patient shown to have a dumbbell tumor in the parasellar and sellar regions by CT scan, showed a high density before contrast, and good enhancement by an iodine contained contrast medium. The tumor had a very high signal intensity in the T2 weighted image of MRI and a good, homogeneous enhancement by Gadolinium-DTPA, yet a carotid angiogram showed it was avascular. Surgical removal was abandoned in view of the probability of massive bleeding. The second case was a 34-year-old man, who had had a skin hemangioma on the right side of the face since his childhood. For the past 3 months, he had suffered from ptosis, and limitation of eye movement which was found to be due to 3rd and 4th cranial nerve palsy. CT showed a good enhanced tumor mass in the left side of the parasellar region with sellar extension. MRI also showed a high intensity in T2WI and good, homogeneous enhancement by Gadolinium-DTPA. A carotid angiogram revealed some tumor stain. Surgical removal. in this case, was also impossible due to its intracavernous sinus location and the probability of massive bleeding.
 ...
PMID:[CT and MRI of parasellar cavernous hemangioma in two cases]. 135 66

The first patient was a 37-year-old man with an invasive and lymphoid cell dominant thymoma (stage III). He underwent extended total thymectomy and partial resection of the upper lobe of the left lung. Four years after the operation, he had ptosis and diplopia and was diagnosed as having myasthenia gravis (positive Tensilon test and raised antiacetylcholine receptor antibody titer). His symptoms improved with the steroid therapy. The second patient was a 37-year-old woman with an invasive and mixed type thymoma (stage III). Extended total thymectomy with combined resection of the mediastinal pleura and right phrenic nerve was performed, but the tumor recurred in the right thorax 2 years postoperatively. Subtotal resection of the parietal pleura and recurrent tumors was performed by right thoracotomy, and steroid therapy was given. She developed malaise, ptosis and diplopia three months later, and was diagnosed as having myasthenia gravis. Her symptoms disappeared after the steroid therapy was stopped. A review of the Japanese literature is presented and problems regarding the pathogenesis of this disease are discussed.
 ...
PMID:[Two cases of post-thymectomy myasthenia gravis]. 140

A rare case of malignant melanoma metastatic to the cavernous sinus and skull, with an unknown primary origin, is reported. A 46-year-old man noticed diplopia, lt. ptosis and swelling in the parietal and maxillary regions. The parietal skull tumor and the maxillary lymph node were excised and histological examination revealed malignant melanoma. Because of its roentogenological characteristics, the lesion of the cavernous sinus was also thought to be the site of metastasis of malignant melanoma. This case is rare because the initial symptom was cavernous sinus syndrome, and no involvement of brain parenchyma was observed.
 ...
PMID:[Malignant melanoma metastatic to the cavernous sinus and skull with an unknown primary origin: report of a case]. 140 54


1 2 3 4 5 6 7 8 9 10 Next >>