Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0033377 (prolapse)
 11,717 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We reported six patients with Marfan's syndrome, studied retrospectively from May 1990 to April 1992 in the department of Cardiology in Dakar. Morphological, cardiovascular, skeletal and ocular abnormalities have been reviewed. All the patients had been evaluated by echocardiography. Prevalence of Marfan's syndrome among congenital heart diseases during this period was 4.8%. The mean age was 27.6 years. The mean height was 1.80 m (range 1.38-2.02 m) for a mean weight of 62.8 kg. All the patients had dolichostenomely and arachnodactyly. Kyphosis or scoliosis was present in 5 cases. Chest deformities (pectus carinatum and excavatum) were present in 5 cases. 5 patients had hyperextensible joints. 5 patients had ocular abnormalities. Cardiac pathology was found in 5: mitral prolapse with insufficiency in 2; mitral prolapse with aortic dystrophy in 2; and isolated dilatation of ascending aorta in an other. One patient with diffuse Marfan's syndrome died of cardiac failure. Our study confirm polymorphic manifestations of Marfan's syndrome and the frequency of cardiac abnormalities which are the major determinants of life-prognosis in these patients. Echocardiography is very useful as a noninvasive method for defining the extent of cardiovascular involvement and following its course, for more appropriate treatment.
Dakar Med 1994
PMID:[Cardiovascular manifestations of Marfan's syndrome apropos of 6 cases]. 865 85

We report a case with ruptured aneurysm of the sinus of Valsava into the right ventricle, diagnosed during heart failure in a 22 years old patient. Etiology and prognosis based on our observation and the literature are discussed. Our patient benefited from clinical examination, ECG (15 derivations), pulmonary X ray and standard laboratory test. Pulsed-Doppler and contrast echocardiography have been realized with an ATL MK 600 echocardiograph. These data are discussed and compared to the literature. Cardiac examination revealed a continuous murmur predominantly diastolic 5/6 and an increase of peripheral artery pulsatility. Chest x-ray showed cardiomegaly and ECG bilateral atrial and left ventricular hypertrophy. Two-dimensional echocardiography revealed the diastolic prolapse of an aneurysmal right coronary sinus in the right ventricle. The rupture was confirmed by contrast echocardiography and pulsed-Doppler. Rupture which is a major complication of aneurysm of the sinus of Valsava, is the usual feature of detection. The consequences of rupture are heart failure and pulmonary edema. Our observation shows that conventional Doppler and contrast echocardiography are important for diagnosis and follow-up of aneurysm of the sinus of Valsava. Aortography, hemodynamic and angiocardiographic data, are also important for a precise diagnosis and the detection of associated malformations when pre-operative investigations of aneurysm of the sinus of valsava are needed.
Dakar Med 1996
PMID:[Rupture of a sinus of Valsalva aneurysm into the right ventricle. A case report in the cardiology clinic at the University Hospital Center of Dakar]. 982 1

There are many variants in vaginal hysterectomy procedures owing to precises indications. We have performed a total vaginal hysterectomy procedure which technique is described herein. Our procedure was using the preexisting anatomic structures. It allows a solid cure adapted to each compound of the genital prolapse. Among a series of 10 cases, we report few complications. An important peroperative bleeding occurred in one case. The postoperative morbidity included 1 case of genital infection and 1 case of urinary fistula. One patient died from a cause not reliable to the procedure. The mean duration of the hospital stay was 10 days. After 2 years follow up, 9 of our patients have good anatomical and functional results. The shortness of this series does not allow us to concluded definitively. However, our results are comparable with those reported in the literature.
Dakar Med 1998
PMID:[Total vaginal hysterectomy for genital prolapse apropos of 10 cases]. 982 70

Vaginal total hysterectomy get to better qualily of lite to patients who have genital prolapse. It gives no abdominal scar. The feeding and rising are early. Among a serie of 36 total vaginal hysterectomies for hysteroceles we performed, we report few complications. One patient presented a plentiful peroperative haemorrhage : three others present a vesical wound. We report one case of releasing suture, one had setting of bladderand one case of vaginal infection. One patient died from a cause not reliable to the procedure. The mean duration of the hospital stay was 8.36 days. After 4 years following up, 2 patients have elytrocele recurrence, and one other presents a bad reducing of cystocele. We hope to pursue this serie strenghen then our results.
Dakar Med 2001
PMID:[Vaginal hysterectomy for hysterocele (report of 36 cases)]. 1577 84

Tolosa-Hunt syndrome is a painful ophthalmoplegia characterized by recurrent unilateral orbital pain, ipsilateral oculomotor paralysis, and a rapid response to steroids. Our report describes a 37-year-old young woman who presented with right ptosis, ipsilateral ophthalmoplegia, and painful headache with no other neurological deficits in which all biological and neuroimaging investigations were normal. Complete recovery within one week of corticosteroid therapy was observed. This is probably the first case of Tolosa-Hunt syndrome reported in Dakar, Senegal.
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PMID:Tolosa-Hunt Syndrome: A Painful Ophthalmoplegia. 3320 52