Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0033036 (APC)
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Human Gene/Protein
USP37 protein 11.6
LONRF2 11.6
ZNF430 11.6
CDRT15 11.6
APC 11.6
ZBTB22 11.6
HIRF6 11.6
leucine zipper protein 3 11.6
KIAA1821 11.6
KIAA0028 11.6
CORT protein 11.6
trigger of mitotic entry 1 11.6
ASEF2 11.6
ZNF584 11.6
leucine-rich repeat-containing 2 11.6
C6orf80 11.6
GCST 11.6
CDRT1 11.6
XAP135 11.6
CENTG3 11.6
NPD008 11.6
T-cell lymphoma breakpoint-associated target 1 11.6
APC7 11.3
APC8 11.3
anaphase-promoting complex/cyclosome 11.3
APC3 11.1
tumor suppressor APC 10.9
APC4 10.9
KEN 10.6
ZNF688 10.6
MYH mRNA 10.6
MFSD9 10.6
MAD2L1 binding protein 10.6
HCC5 10.6
ABTB2 10.6
IL-12R-beta2 10.6
HDNB1/UFD2 10.6
FLJ22729 10.6
CCDC84 10.6
TAP binding protein 10.6
golgin-like protein 10.6
ANKRD45 10.6
VHL-like protein 10.6
Protein tyrosine phosphatase, receptor type, C 10.6
killer cell lectin-like receptor subfamily G, member 1 10.6
UBE2V 10.6
early mitotic inhibitor 1 10.6
H4F2 10.6
ZNF767 10.6
BING4 10.6
B-cell CLL/lymphoma 9 protein 10.6
DUX5 10.6
AURKAIP1 10.6
CCDC15 10.6
KIAA0215 10.6
VWS1 10.6
APC5 10.5
APC10 10.5
EMI2 10.4
FZR1 10.4
SWM1 10.4
UBE2S 10.4
mixed lineage kinase 4 10.3
APC11 10.3
EMI1 10.2
APC protein 10.0
LTM1 10.0
CNBD1 10.0
cytochrome b5 reductase-like 10.0
C17orf25 10.0
target of myb 1 10.0
ZSWIM7 10.0
RBM44 10.0
ZNF34 10.0
MGC13061 10.0
CENTA2 10.0
HMG1L1 10.0
C11orf65 10.0
PRR15 10.0
PPP2R3 10.0
more...
Disease
APC 11.6
MLVI2 11.6
ASPG1 10.6
Duodenal polyposis 10.6
Duodenal mass 10.6
MYH-associated polyposis 10.2
GFND 10.0
Activated protein C resistance 9.9
DFN6 9.6
Serrated adenoma 9.5
AAPC 9.4
CCAL2 9.3
Aberrant Crypt Foci 9.3
Adenocarcinoma of the gastroesophageal junction 9.0
Turcot syndrome 8.8
familial adenomatous polyposis 8.8
MHS6 8.8
Duodenal cancer 8.6
AIH2 8.4
Periampullary carcinoma 8.4
Gastric adenoma 8.4
Corpus uteri 8.4
EJM1 8.3
Seasonal allergic conjunctivitis 8.3
FRA11B 8.2
bee sting allergy 8.1
GVM 8.1
Serum potassium increased 8.0
Permanent junctional reciprocating tachycardia 8.0
HNPCC 7.9
KAL2 7.9
DFNB10 7.9
HPCX 7.8
Thyroid Carcinoma 7.8
BPES 7.8
Complete right bundle branch block 7.6
Gastric polyps 7.6
Vaccinia virus infection 7.5
AIMAH 7.5
Gardner's syndrome 7.5
polyposis 7.5
RP13 7.4
desmoid 7.3
HRPT2 7.3
Cerebellar liponeurocytoma 7.3
Myeloma cast nephropathy 7.3
Factor V Leiden mutation 7.3
Congenital hypertrophy of the retinal pigment epithelium 7.2
Junctional ectopic tachycardia 7.2
DFNB8 7.2
Goblet cell carcinoid 7.2
Multiple cancer 7.1
Lynch syndrome 7.1
PC deficiency 7.1
inv(X) 7.1
biliary neoplasm 7.0
DFNB7 6.9
AV nodal tachycardia 6.9
Merkel cell carcinoma 6.8
Hidradenoma papilliferum 6.8
RP6 6.8
Therapy-related myelodysplastic syndrome 6.8
MIN 6.7
MIN 6.7
Rhabdoid meningioma 6.7
XPE 6.7
adrenal disorder 6.6
SA block 6.6
HPC1 6.5
MSSD 6.5
sulfhemoglobinemia 6.5
adenomatous polyp 6.5
MSS 6.5
familial cancer 6.5
Catastrophic Illness 6.5
Adenoma 6.5
Adenoma 6.5
Protein S deficiency 6.5
Idiopathic pneumonia syndrome 6.4
ependymal tumors 6.4
more...
Symptom
Cri du chat 8.8
Gasping 5.7
Functional constipation 5.7
trigeminy 5.0
bewilderment 4.8
bigeminal 4.6
impaired motor coordination 4.0
anal pain 3.7
DNA marker 3.3
leg edema 3.2
hyperacusis 3.1
intestinal bleeding 3.0
Respiratory symptoms 2.7
HSA 2.6
syncopal episodes 2.6
physical appearance 2.6
clumsiness 2.5
chills 2.4
fasciculation 2.3
exertional angina 2.1
chest tightness 2.0
constipation 2.0
decreased appetite 1.4
hypertonia 1.3
chronic constipation 1.3
Sedation 1.2
hypotonia 1.1
functional recovery 1.1
starvation 1.0
despair 1.0
torticollis 0.9
bloating 0.9
nausea and vomiting 0.7
hepatomegaly 0.7
splenomegaly 0.7
twitching 0.6
blurred vision 0.6
flushing 0.6
stridor 0.4
pallor 0.3
acidity 0.3
shortness of breath 0.3
Wind 0.3
dry eye 0.2
exhaustion 0.2
chest pain 0.1
diarrhea 0.1
cancer pain 0.0
abdominal pain -0.0
colic -0.0
spasticity -0.1
erythema -0.1
epigastric pain -0.1
cerebellar ataxia -0.2
memory loss -0.2
Ill -0.3
thinning -0.3
nausea -0.3
vomiting -0.4
hemiplegia -0.4
headache -0.4
agitation -0.4
apathy -0.4
collapse -0.4
hypothermia -0.5
numbness -0.7
angina -0.8
ENT -0.8
weakness -0.8
dyspnea -0.8
cachexia -0.9
lethargy -0.9
fatigue -0.9
hemoptysis -1.0
sleepiness -1.0
tinnitus -1.1
analgesia -1.2
seizures -1.2
pain -1.3
anesthesia -1.3
more...
Drug
Efaproxiral sodium 11.6
Edodekin alfa 11.6
Selodenoson 11.6
Zofenopril calcium 9.8
Motexafin lutetium 9.3
APD-356 8.8
Percodan 8.6
Zanolimumab 8.3
Parecoxib sodium 8.1
Torecan 8.0
Torecan 8.0
Fosamprenavir calcium 7.9
Valdecoxib 7.7
Valcyte 7.6
Zomepirac sodium 7.6
Hemolink 7.5
Bextra 7.4
Mexitil 7.4
Provenge 7.4
Mexitil 7.2
Ziprasidone hydrochloride 7.2
Ecallantide 7.1
PT-141 7.1
Ximelagatran 7.1
Betamethasone dipropionate 6.7
Potassium canrenoate 6.7
Palonosetron hydrochloride 6.5
Warfarin sodium 6.2
Nesiritide 6.2
Eszopiclone 6.1
Zofran 6.1
Clemastine 6.1
Vioxx 6.1
Pegasys 6.1
Irinotecan 6.0
Beraprost 5.9
Frovatriptan 5.8
Genasense 5.8
Efalizumab 5.8
Zofran 5.7
Efalizumab 5.7
Abatacept 5.6
Dextran sulfate sodium 5.6
Levitra 5.4
IFN-gamma 5.4
FCV 5.3
IL-2 5.3
Rasagiline 5.3
Copaxone 5.3
CPT-11 5.3
Calcipotriol 5.3
Lipitor 5.2
Darbepoetin alfa 5.2
Tegaserod 5.2
Olmesartan medoxomil 5.2
Rasburicase 5.2
Ziconotide 5.1
APM 5.1
Pirarubicin 5.1
Sodium thiosulfate 5.0
Neocarzinostatin 4.8
Lipitor 4.8
Lipitor 4.8
CIA 4.8
Intron A 4.8
Belatacept 4.7
Kaolin 4.7
Dalbavancin 4.7
Celebrex 4.7
Ranolazine 4.6
Ranolazine 4.6
FSH-beta 4.6
Peracetic acid 4.6
SMP 4.6
CDX 4.6
FSH-beta 4.6
Intron A 4.6
Intron A 4.5
PTC 4.5
Epoetin 4.5
more...
Enzyme
APC 10.6
separase 8.6
STK11 8.2
phycocyanobilin:ferredoxin oxidoreductase 7.5
vibriolysin 7.2
granzyme M 6.7
polo-like kinase 1 6.6
ubiquitin-protein ligase 6.0
PRA 5.8
pyruvate decarboxylase 5.8
carboxypeptidase D 5.7
Delta6-desaturase 5.6
deoxyhypusine hydroxylase 5.6
MHCK 5.5
caspase-5 5.4
ethanolamine ammonia-lyase 5.4
bleomycin hydrolase 5.2
cathepsin S 5.2
beta-agarase 5.2
TSR 5.1
CYP8B1 5.1
caspase-5 5.1
N-acetylglucosaminyltransferase III 5.0
penicillin acylase 4.9
dynamin GTPase 4.9
peptidyl-tRNA hydrolase 4.9
alpha-methylacyl-CoA racemase 4.8
polyphosphatase 4.8
ADE2 4.8
GTI 4.7
GSK 4.7
cdc2 4.6
TGT 4.6
tripeptidase 4.6
PWD 4.6
thymidylate kinase 4.4
PAM 4.4
malonyl-CoA decarboxylase 4.4
cathepsin X 4.4
prephenate dehydratase 4.4
proteasome 4.3
type 1 protein phosphatase 4.2
SMP 4.2
Lys4 4.2
spermine synthase 4.1
CNPase 4.1
fructose-2,6-bisphosphatase 4.1
proteinase A 4.1
CLK1 4.1
tryptase 4.1
histidyl-tRNA synthetase 4.0
prostacyclin synthase 4.0
phytoene synthase 4.0
granzyme B 4.0
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.0
naphthalene dioxygenase 4.0
RNase PH 4.0
BAT 3.9
AAE 3.9
acetolactate synthase 3.9
aminopeptidase P 3.9
cysteine dioxygenase 3.8
acylase 3.8
eEF2 kinase 3.7
alanine aminopeptidase 3.7
insulin-degrading enzyme 3.7
proteinase A 3.5
leucyl-tRNA synthetase 3.4
carboxylesterase 3.4
TSA 3.4
methylenetetrahydrofolate reductase 3.4
protein phosphatase 2A 3.4
methylenetetrahydrofolate reductase 3.4
thrombin 3.3
protoporphyrinogen oxidase 3.3
PAL 3.3
6-phosphofructo-2-kinase 3.2
ADP-ribosyltransferase 3.2
thromboplastin 3.2
Der p 1 3.2
more...
Compound
PAC 11.1
C8H9N3O3 10.6
C7H14O 10.6
1H-imidazo[4,5-b]pyrazine 10.6
Phenylacetylcarbinol 10.2
Aspidospermine 10.0
Aspidospermine 10.0
3H-[1,2,3]triazolo[4,5-b]pyridine 10.0
5-aminopentanoic acid 9.7
C11H12N2O 9.6
[1,2,4]triazolo[4,3-a]pyrazine 9.6
[1,2,4]triazolo[4,3-a]pyrimidine 9.3
Acid Blue 45 9.3
S-51 9.0
[1,2,4]triazolo[4,3-c]pyrimidine 8.8
MDMS 8.1
Disopyramide phosphate 8.0
Nelfinavir mesylate 8.0
Torecan 8.0
Genkwanin 7.8
2-hydroxydodecanoic acid 7.6
Pac 7.6
Ailanthone 7.5
Dictamnine 7.5
FAP 7.5
FAP 7.5
DCC 7.4
Amarogentin 7.4
Benzanthrone 7.4
Ailanthone 7.2
Microcephalin 7.1
E09 7.1
Ferron 7.1
E09 7.1
CHBr2Cl 7.0
4-fluorobenzaldehyde 7.0
4-fluorobenzaldehyde 7.0
nicotine-1'-N-oxide 6.9
Neohesperidin 6.6
Paraformaldehyde 6.6
Caprolactam 6.5
Stearidonic acid 6.4
Blasticidin S 6.4
SN-38 6.4
hexyl acrylate 6.3
Novex 6.3
Mafosfamide 6.2
Sulindac 6.2
Paraformaldehyde 6.2
1H-pyrazolo[3,4-d]pyrimidine 6.2
Azoxymethane 6.2
C14H19N3O4 6.2
Clemastine 6.2
Homoharringtonine 6.1
Bromodichloromethane 6.0
Brucine 6.0
2-methyl-2-butanol 6.0
Moricizine 5.9
Pristimerin 5.9
Pristimerin 5.9
Pristimerin 5.9
Pristimerin 5.9
Alantolactone 5.8
Desogestrel 5.7
10-Hydroxycamptothecin 5.6
2-naphthaldehyde 5.6
TRU 5.6
3-hydroxydecanoic acid 5.6
MGA 5.5
CLTC 5.5
Garcinol 5.5
EPB 5.5
Urocanic acid 5.5
Leupeptin 5.5
C 10 5.5
C 10 5.4
2,6-dimethoxyphenyl 5.4
F23 5.4
Tuberin 5.4
9Z,11E-octadecadienoic acid 5.3
more...