Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0033036 (APC)
10,214 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
APC 8035
p53 803
Sep 657
CD4 598
Mol 529
TCR 518
MHC 493
anaphase-promoting complex/cyclosome 451
beta-catenin 445
cytokine 426
IFN-gamma 399
catenin 390
IL-2 375
CD8 374
MHC class II 356
ubiquitin 309
KRAS 302
ubiquitin ligase 293
cyclin 246
IL-4 239
CD28 221
IL-10 221
adenomatous polyposis coli 206
CTNNB1 196
proteasome 180
BRAF 179
CD40 168
E3 ubiquitin ligase 167
MHC class I 165
E-cadherin 164
p16 161
CD86 156
CDH1 153
lymphoid 148
CD80 144
securin 143
PTEN 135
MLH1 135
HLA 133
protein C 132
K-ras 131
DCC 128
PIK3CA 128
LPS 123
BRCA1 123
IFN 121
SMAD4 114
RASSF1A 111
thrombin 109
IL-6 108
Mad2 104
Axin 104
cyclin B1 103
TNF-alpha 103
pituitary adenylate cyclase-activating polypeptide 101
MCC 97
protein S 96
SCF 96
HLA-DR 96
CDKN2A 95
CD11c 94
cyclin D1 94
factor V 94
tumour suppressor 93
methylguanine-DNA methyltransferase 92
ICAM-1 91
TCF 88
thymus 86
MSH2 84
BRCA2 84
FISH 83
hMLH1 83
MUTYH 82
GSTP1 82
TNF 81
renin 81
ATM 79
ras 79
insulin 77
EGFR 77
more...
Disease
APC 10214
cancer 2036
tumor 1833
colorectal cancer 925
familial adenomatous polyposis 632
carcinogenesis 493
tumorigenesis 480
carcinoma 409
colon cancer 345
adenoma 294
polyposis 282
adenocarcinoma 224
breast cancer 165
tumor progression 147
tumor growth 122
metastases 120
dysplasia 110
gastric cancer 109
Merkel cell carcinoma 97
Lynch syndrome 90
desmoid 89
influenza 86
HIV 85
ATM 83
prostate cancer 80
lung cancer 78
hepatocellular carcinoma 77
melanoma 76
encephalomyelitis 74
diabetes 74
ovarian cancer 73
systemic lupus erythematosus 73
leukemia 69
lymphoma 64
lupus 60
autoimmune disease 57
lupus 51
Hippel 51
virus infection 51
multiple sclerosis 50
tetanus 41
squamous cell carcinoma 41
ulcerative colitis 41
primary tumor 41
colitis 40
epithelial ovarian cancer 40
non-small cell lung cancer 40
cold 39
rectal cancer 39
retinoblastoma 39
HNPCC 39
stroke 39
hypertension 39
Barrett's esophagus 38
Gardner's syndrome 38
infectious diseases 38
inflammatory bowel disease 37
deep vein thrombosis 37
pancreatic cancer 37
type 1 diabetes 36
Mycobacterium 36
PHA 33
asthma 33
NOD 32
hepatoblastoma 31
tuberculosis 30
WT1 29
sepsis 29
Alzheimer's disease 29
mental retardation 28
mental retardation 28
Activated protein C resistance 28
tumor initiation 28
sepsis 27
medulloblastoma 27
STS 27
anemia 26
bladder cancer 26
papillary thyroid cancer 26
hepatitis B 26
more...
Symptom
pain 34
diarrhea 20
starvation 16
headache 14
anesthesia 14
constipation 13
seizures 11
abdominal pain 10
functional recovery 9
fatigue 9
vomiting 8
chills 7
weakness 7
collapse 7
chest pain 6
nausea 6
acidity 6
HSA 6
dyspnea 5
exhaustion 5
splenomegaly 5
nausea and vomiting 5
angina 4
hypotonia 4
hypothermia 4
erythema 4
analgesia 4
cough 3
DNA marker 3
Ill 3
physical appearance 3
thinning 3
hepatomegaly 3
agitation 3
flushing 3
intestinal bleeding 2
spasticity 2
leg edema 2
sleepiness 2
shortness of breath 2
fasciculation 2
blurred vision 1
bloating 1
Gasping 1
discomfort 1
anorexia 1
cachexia 1
ENT 1
bigeminal 1
memory loss 1
pallor 1
trigeminy 1
stridor 1
cerebellar ataxia 1
anal pain 1
hypercapnia 1
syncopal episodes 1
stigma 1
Cri du chat 1
decreased appetite 1
clumsiness 1
hypertonia 1
discomfort 1
dry eye 1
lethargy 1
twitching 1
tinnitus 1
colic 1
respiratory distress 1
hemiplegia 1
ataxia 1
bewilderment 1
overweight 1
exertional angina 1
Respiratory symptoms 1
torticollis 1
epigastric pain 1
back pain 1
apathy 1
numbness 1
more...
Drug
IFN-gamma 398
IL-2 375
CSF 90
lysine 43
CPT-11 24
Dermatol 22
MAP 19
caffeine 18
Irinotecan 17
Cardiovasc 14
PTC 13
Monit 12
Adriamycin 11
Asn 11
EPA 10
ROS 8
G-CSF 8
CIA 7
MDS 7
CAM 7
Leaf 7
Gel 7
ROC 7
BLM 7
Bevacizumab 6
CaCl2 6
Valdecoxib 6
ENT 6
Ximelagatran 6
FeCl3 6
CaCl2 6
CaCl2 6
ZnO 6
vitamin E 5
CTC 5
uPA 5
TAT 5
Taxol 5
CTX 5
Gleevec 4
IFN-beta 4
Asthma 4
p75 4
PCP 4
Parkin 4
THF 4
IL-11 4
ACT 4
Parkin 4
Nephron 4
CTC 4
Captopril 4
Carotenoid 4
NH3 4
G418 4
Copaxone 4
Imatinib 4
Paraffin 3
FAD 3
ABC 3
TAC 3
Provenge 3
Meth 3
Phosphatidylserine 3
ETS 3
Abatacept 3
DM1 3
SMP 3
Forskolin 3
GRF 3
Docetaxel 3
Gefitinib 3
ADR 3
ADM 3
CTA 3
Bifidobacterium 3
EPI 3
nitroglycerin 3
Vioxx 3
EE2 3
more...
Enzyme
APC 8035
ERK 269
proteasome 183
protein kinase 165
mitogen-activated protein kinase 132
thrombin 107
focal adhesion kinase 84
renin 81
cdc2 65
GSK 55
lysozyme 49
adenylate cyclase 49
protein kinase C 49
polo-like kinase 1 49
STK11 45
separase 42
thromboplastin 39
MEK 38
luciferase 36
calcineurin 34
PRA 30
trypsin 27
caspase-3 25
PARP 24
ATPase 21
RNA polymerase 19
phospholipase C 19
glutathione S-transferase 18
granzyme B 17
reverse transcriptase 17
ubiquitin-protein ligase 16
DNA polymerase 16
catalase 16
ACS 16
tissue plasminogen activator 15
tryptase 15
pyruvate dehydrogenase 15
pyruvate decarboxylase 15
alkaline phosphatase 14
MAP 14
DNA methyltransferase 14
neuraminidase 14
RNase 13
PAM 13
NO synthase 13
RNase 13
CD10 12
superoxide dismutase 12
phospholipase A2 12
phosphatidylinositol 3-kinase 11
MMP 11
carboxylesterase 10
protein phosphatase 2A 10
beta-galactosidase 10
CaMKII 10
topoisomerase 10
peroxidase 10
kinesin 10
PAH 10
CYP3A4 9
AMPK 9
transcriptase 9
deaminase 9
urokinase-type plasminogen activator 8
plasmin 8
AMP-activated protein kinase 8
topoisomerase 8
beta-glucuronidase 8
phosphodiesterase 8
gamma-glutamyl transpeptidase 7
methylenetetrahydrofolate reductase 7
prostate-specific antigen 7
cathepsin D 7
MIP 7
methylenetetrahydrofolate reductase 7
kallikrein 7
collagenase 7
PAL 6
AMPK 6
thymidine kinase 6
more...
Compound
Pac 2065
PAC 2056
DNA 1301
Dec 736
Clin 339
water 233
calcium 153
sodium 130
DCC 128
tyrosine 110
oxygen 100
aldosterone 97
TNF 81
arginine 81
glucose 72
lysine 65
cAMP 63
serine 59
FAP 58
FAP 58
sulfate 57
methionine 55
nitrogen 53
cysteine 50
potassium 47
threonine 47
alanine 46
phosphate 45
salt 43
His 42
hydrogen 39
urea 39
PMA 38
PMA 36
ATP 36
aluminum 34
zinc 31
acetate 31
NKT 31
ammonium 30
galactose 30
MTT 29
SN-38 29
nitric oxide 29
GTP 28
NH2 28
leucine 27
iodine 26
MEK 26
CPT-11 24
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
PAS 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
benzaldehyde 23
more...