Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0033036 (
APC
)
10,214
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
APC
8035
p53
803
Sep
657
CD4
598
Mol
529
TCR
518
MHC
493
anaphase-promoting complex/cyclosome
451
beta-catenin
445
cytokine
426
IFN-gamma
399
catenin
390
IL-2
375
CD8
374
MHC class II
356
ubiquitin
309
KRAS
302
ubiquitin ligase
293
cyclin
246
IL-4
239
CD28
221
IL-10
221
adenomatous polyposis coli
206
CTNNB1
196
proteasome
180
BRAF
179
CD40
168
E3 ubiquitin ligase
167
MHC class I
165
E-cadherin
164
p16
161
CD86
156
CDH1
153
lymphoid
148
CD80
144
securin
143
PTEN
135
MLH1
135
HLA
133
protein C
132
K-ras
131
DCC
128
PIK3CA
128
LPS
123
BRCA1
123
IFN
121
SMAD4
114
RASSF1A
111
thrombin
109
IL-6
108
Mad2
104
Axin
104
cyclin B1
103
TNF-alpha
103
pituitary adenylate cyclase-activating polypeptide
101
MCC
97
protein S
96
SCF
96
HLA-DR
96
CDKN2A
95
CD11c
94
cyclin D1
94
factor V
94
tumour suppressor
93
methylguanine-DNA methyltransferase
92
ICAM-1
91
TCF
88
thymus
86
MSH2
84
BRCA2
84
FISH
83
hMLH1
83
MUTYH
82
GSTP1
82
TNF
81
renin
81
ATM
79
ras
79
insulin
77
EGFR
77
more...
Disease
APC
10214
cancer
2036
tumor
1833
colorectal cancer
925
familial adenomatous polyposis
632
carcinogenesis
493
tumorigenesis
480
carcinoma
409
colon cancer
345
adenoma
294
polyposis
282
adenocarcinoma
224
breast cancer
165
tumor progression
147
tumor growth
122
metastases
120
dysplasia
110
gastric cancer
109
Merkel cell carcinoma
97
Lynch syndrome
90
desmoid
89
influenza
86
HIV
85
ATM
83
prostate cancer
80
lung cancer
78
hepatocellular carcinoma
77
melanoma
76
encephalomyelitis
74
diabetes
74
ovarian cancer
73
systemic lupus erythematosus
73
leukemia
69
lymphoma
64
lupus
60
autoimmune disease
57
lupus
51
Hippel
51
virus infection
51
multiple sclerosis
50
tetanus
41
squamous cell carcinoma
41
ulcerative colitis
41
primary tumor
41
colitis
40
epithelial ovarian cancer
40
non-small cell lung cancer
40
cold
39
rectal cancer
39
retinoblastoma
39
HNPCC
39
stroke
39
hypertension
39
Barrett's esophagus
38
Gardner's syndrome
38
infectious diseases
38
inflammatory bowel disease
37
deep vein thrombosis
37
pancreatic cancer
37
type 1 diabetes
36
Mycobacterium
36
PHA
33
asthma
33
NOD
32
hepatoblastoma
31
tuberculosis
30
WT1
29
sepsis
29
Alzheimer's disease
29
mental retardation
28
mental retardation
28
Activated protein C resistance
28
tumor initiation
28
sepsis
27
medulloblastoma
27
STS
27
anemia
26
bladder cancer
26
papillary thyroid cancer
26
hepatitis B
26
more...
Symptom
pain
34
diarrhea
20
starvation
16
headache
14
anesthesia
14
constipation
13
seizures
11
abdominal pain
10
functional recovery
9
fatigue
9
vomiting
8
chills
7
weakness
7
collapse
7
chest pain
6
nausea
6
acidity
6
HSA
6
dyspnea
5
exhaustion
5
splenomegaly
5
nausea and vomiting
5
angina
4
hypotonia
4
hypothermia
4
erythema
4
analgesia
4
cough
3
DNA marker
3
Ill
3
physical appearance
3
thinning
3
hepatomegaly
3
agitation
3
flushing
3
intestinal bleeding
2
spasticity
2
leg edema
2
sleepiness
2
shortness of breath
2
fasciculation
2
blurred vision
1
bloating
1
Gasping
1
discomfort
1
anorexia
1
cachexia
1
ENT
1
bigeminal
1
memory loss
1
pallor
1
trigeminy
1
stridor
1
cerebellar ataxia
1
anal pain
1
hypercapnia
1
syncopal episodes
1
stigma
1
Cri du chat
1
decreased appetite
1
clumsiness
1
hypertonia
1
discomfort
1
dry eye
1
lethargy
1
twitching
1
tinnitus
1
colic
1
respiratory distress
1
hemiplegia
1
ataxia
1
bewilderment
1
overweight
1
exertional angina
1
Respiratory symptoms
1
torticollis
1
epigastric pain
1
back pain
1
apathy
1
numbness
1
more...
Drug
IFN-gamma
398
IL-2
375
CSF
90
lysine
43
CPT-11
24
Dermatol
22
MAP
19
caffeine
18
Irinotecan
17
Cardiovasc
14
PTC
13
Monit
12
Adriamycin
11
Asn
11
EPA
10
ROS
8
G-CSF
8
CIA
7
MDS
7
CAM
7
Leaf
7
Gel
7
ROC
7
BLM
7
Bevacizumab
6
CaCl2
6
Valdecoxib
6
ENT
6
Ximelagatran
6
FeCl3
6
CaCl2
6
CaCl2
6
ZnO
6
vitamin E
5
CTC
5
uPA
5
TAT
5
Taxol
5
CTX
5
Gleevec
4
IFN-beta
4
Asthma
4
p75
4
PCP
4
Parkin
4
THF
4
IL-11
4
ACT
4
Parkin
4
Nephron
4
CTC
4
Captopril
4
Carotenoid
4
NH3
4
G418
4
Copaxone
4
Imatinib
4
Paraffin
3
FAD
3
ABC
3
TAC
3
Provenge
3
Meth
3
Phosphatidylserine
3
ETS
3
Abatacept
3
DM1
3
SMP
3
Forskolin
3
GRF
3
Docetaxel
3
Gefitinib
3
ADR
3
ADM
3
CTA
3
Bifidobacterium
3
EPI
3
nitroglycerin
3
Vioxx
3
EE2
3
more...
Enzyme
APC
8035
ERK
269
proteasome
183
protein kinase
165
mitogen-activated protein kinase
132
thrombin
107
focal adhesion kinase
84
renin
81
cdc2
65
GSK
55
lysozyme
49
adenylate cyclase
49
protein kinase C
49
polo-like kinase 1
49
STK11
45
separase
42
thromboplastin
39
MEK
38
luciferase
36
calcineurin
34
PRA
30
trypsin
27
caspase-3
25
PARP
24
ATPase
21
RNA polymerase
19
phospholipase C
19
glutathione S-transferase
18
granzyme B
17
reverse transcriptase
17
ubiquitin-protein ligase
16
DNA polymerase
16
catalase
16
ACS
16
tissue plasminogen activator
15
tryptase
15
pyruvate dehydrogenase
15
pyruvate decarboxylase
15
alkaline phosphatase
14
MAP
14
DNA methyltransferase
14
neuraminidase
14
RNase
13
PAM
13
NO synthase
13
RNase
13
CD10
12
superoxide dismutase
12
phospholipase A2
12
phosphatidylinositol 3-kinase
11
MMP
11
carboxylesterase
10
protein phosphatase 2A
10
beta-galactosidase
10
CaMKII
10
topoisomerase
10
peroxidase
10
kinesin
10
PAH
10
CYP3A4
9
AMPK
9
transcriptase
9
deaminase
9
urokinase-type plasminogen activator
8
plasmin
8
AMP-activated protein kinase
8
topoisomerase
8
beta-glucuronidase
8
phosphodiesterase
8
gamma-glutamyl transpeptidase
7
methylenetetrahydrofolate reductase
7
prostate-specific antigen
7
cathepsin D
7
MIP
7
methylenetetrahydrofolate reductase
7
kallikrein
7
collagenase
7
PAL
6
AMPK
6
thymidine kinase
6
more...
Compound
Pac
2065
PAC
2056
DNA
1301
Dec
736
Clin
339
water
233
calcium
153
sodium
130
DCC
128
tyrosine
110
oxygen
100
aldosterone
97
TNF
81
arginine
81
glucose
72
lysine
65
cAMP
63
serine
59
FAP
58
FAP
58
sulfate
57
methionine
55
nitrogen
53
cysteine
50
potassium
47
threonine
47
alanine
46
phosphate
45
salt
43
His
42
hydrogen
39
urea
39
PMA
38
PMA
36
ATP
36
aluminum
34
zinc
31
acetate
31
NKT
31
ammonium
30
galactose
30
MTT
29
SN-38
29
nitric oxide
29
GTP
28
NH2
28
leucine
27
iodine
26
MEK
26
CPT-11
24
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
PAS
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
benzaldehyde
23
more...